Motilak

Мотилак Drug photo

The description is actual on 18.08.2014

  • Latin name: Motilak
  • ATH code: A03FA03
  • Active ingredient: Domperidon (Domperidone)
  • Producer: Russian company "Verofarm"

Structure

One tablet contains in a cover 10 mg of a domperidon and additional substances: aerosil, lactose, carboxymethylstarch of sodium, PVP, microcrystallic cellulose, starch, silicon dioxide, polysorbate-80, titanium dioxide.

One tablet for a rassasyvaniye contains 10 mg of a domperidon and additional components: magnesium stearate, advantoza of FS-95, glucose, starch, carboxymethylstarch and fragrance (mint natural oil).

Release form

The medicine is issued in the tableted form: tablets for a rassasyvaniye and the tablets covered with a special cover. In each cardboard pack there are 30 tablets (3 blisters on 10 pieces).

Pharmacological action

In the structure the operating component domperidon is similar to neuroleptics, and by efficiency is comparable with Metoclopramidum. Active agent practical does not exert impact on expressiveness of gastric secretion and is not capable to cause extrapyramidal frustration.

Due to increase in time of reduction of walls of a duodenum and a stomach, the medicine exerts positive impact on a digestive tract peristaltics. Medicine accelerates gastric emptying, without detaining a food lump.

Thanks to strengthening of a tone of a gastroesophageal sphincter the antiemetic effect is reached.

Pharmacodynamics and pharmacokinetics

Active agent after intake is soaked up quickly. Biological availability about 15% (low). At the lowered acidity of a gastric juice absorption of the operating component decreases. The peak of concentration is registered in 60 minutes. Communication with plasma proteins makes 93%.

Drug gets into all body tissues, small concentration is registered also in a brain. In a liver intestines walls the medicine is exposed to an intensive metabolism. An elimination half-life – 7-9 hours.

Indications to Motilak's use

From what drug Motilak? The medicine is actively appointed at:

From what tablets of a domperidon can be appointed:

Indications to use for patients with Parkinson's illness: nausea against reception of the Levodopa and Bromocriptinum.

Contraindications

The medicine is not appointed at:

  • bleedings in a digestive tract;
  • individual hypersensitivity to derivatives of a domperidon;
  • mechanical impassability of a gastrointestinal tract;
  • perforation in the alimentary system;
  • diagnosing of a prolaktinoma.

Side effects

  • skin rashes;
  • gynecomastia;
  • extrapyramidal frustration (in pediatrics);
  • enterospasms;
  • anaphylaxis;
  • small tortoiseshell.

Application instruction of Motilak (Way and dosage)

How to appoint medicine Motilak?

Application instruction: a daily dose – 30 mg; one-time – 10 mg. The medicine is recommended to be accepted in 30 minutes prior to food. Tablets for a rassasyvaniye need to be held in an oral cavity before full dissolution; tablets in a cover cannot be broken, divided and chewed. In isolated cases the daily quantity of a medicine can be increased to 60 mg.

To children (weight 20-30kg) 2 times a day appoint ½ tablets. Weighing more than 30 kg is appointed on 1 tablet twice a day.

Overdose

Extrapyramidal frustration, the increased drowsiness, disorientation in space and time are registered. Purpose of enterosorbents is recommended (absorbent carbon), a timely gastric lavage, purpose of posindromny therapy.

Antihistaminic medicines help to stop extrapyramidal disturbances.

Interaction

Anti-secretory means and antacids are capable to make negative impact on biological availability of Motilak.

M-holinoblokatory reduce ability of a medicine concerning evakuatorny activity of a stomach and intestines.

HIV protease inhibitors, nefazodon, macroleads and drugs of an azolovy row increase the level of a domperidon in blood.

Terms of sale

OTC medicine.

Storage conditions

To protect from moisture influence. The temperature condition recommended by the producer – no more than 25 degrees.

Period of validity

2 years.

Special instructions

In need of simultaneous therapy antacids recommend to maintain a 30-minute interval between receptions of medicines.

What is Motilium or Motilak better?

There is no definite answer. As the operating component in drugs the difference only in producers of medicines acts domperidon.

Motilak's analogs (structural substitutes)

Coincidence on the ATH code of the 4th level:

Motinorm, Motoriks, Peridon, Motorikum. Motilak's analogs are made in Russia and the abroad.

Zdravzona

  • Motilak of 10 mg No. 30 tabletkiverofarm joint stock company
  • Motilak of 10 mg No. 30 of a tablet for rassasyvaniyaverofarm joint stock company
  • Motilak of 10 mg No. 10 of a tablet for rassasyvaniyaverofarm joint stock company

Drugstore of IFC

  • Motilak tbl p / about 10 mg No. 30, Veropharm / the Voronezh branch (Voronezh) Russia
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Section: Gastrointestinal
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Education: Graduated from the Bashkir state medical university majoring in "Medical business". In 2011 gained the diploma and the certificate in Therapy. In 2012 received 2 certificate and the diploma in "Functional diagnosis" and "Cardiology". In 2013 completed courses on "Topical issues of otorhinolaryngology in therapy". In 2014 completed advanced training courses in "A clinical echocardiography" and courses in "Medical rehabilitation".

Experience: From 2011 to 2014 the Policlinic No. 33 Ufa worked as the therapist and the cardiologist in MBUZ. Since 2014 the Policlinic No. 33 Ufa works as the cardiologist and the doctor of functional diagnosis in MBUZ.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Motilak surely consult with the attending physician.