Nazivin

Drug photo

The description is actual on 04.07.2016

  • Latin name: Nasivin
  • ATH code: R01AA05
  • Active ingredient: Oxymetazoline (Oxymetazoline)
  • Producer: Merck KGaA (Germany)

Structure

In 1 ml of drops of oxymetazoline of a hydrochloride of 500 mkg, 250 mkg or 100 mkg. Solution a benzalkoniya of chloride, dihydrophosphate sodium a dihydrate, EDTA, hydroxide sodium, water, hydrophosphate sodium a dihydrate — as excipients.

Composition of spray: in 1 ml of oxymetazoline of a hydrochloride of 500 mkg. Solution a benzalkoniya of chloride, dihydrophosphate sodium a dihydrate, EDTA, hydroxide sodium, water, hydrophosphate sodium a dihydrate — as excipients.

Release form

Drops in bottles with a cover pipette of 0,05% of 0,025% and 0,01%.

Spray of 0,05% in a bottle of 10 ml with the sprayer.

Pharmacological action

Vasoconstrictive.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Vasoconstrictive drug, alfa2-adrenomimetik. Reduces puffiness mucous at topical administration and the number of allocations. Eliminating hypostasis of mucous, recovers breath and aeration of adnexal bosoms and a middle ear. Use of drug prevents development of antritis, sinusitis, otitis.

In therapeutic concentration does not cause a hyperemia and does not irritate mucous membranes. Begins to work in 10 minutes and the effect lasts 12 hours.

Pharmacokinetics

At topical administration has no systemic action. Elimination half-life about 35 h. With urine 2,1%, with a stake of 1,1% are brought.

Indications to use

Contraindications

  • glaucoma;
  • hypersensitivity;
  • atrophic rhinitis;
  • age till 6 flyings (for drug of 0,05%).

With care it is appointed at use of MAO inhibitors, the increased intraocular pressure, severe forms of arterial hypertension and stenocardia, at pregnancy, a thyrotoxicosis.

Side effects

All by-effects arise seldom:

  • sneezing;
  • dryness and burning mucous nose;
  • the reactive hyperemia after the end of treatment which is shown a nose congestion (at overdose);
  • sleeplessness;
  • concern;
  • headache;
  • nausea;
  • tachycardia and arterial hypertension (at overdose);
  • atrophy of mucous membranes (at overdose).

Application instruction of Nazivin (Way and dosage)

Spray Nazivin, application instruction

Spray of 0,05% is appointed to adults and children since 6. About 1 injection in the nasal courses 2–3 times a day is recommended. In the recommended dose it is possible to apply till 7 days. If symptoms amplify within 3 days, it is necessary to see a doctor.

Drops Nazivin, application instruction

To adults and children since 6 appoint 0,05% of a drop on 1-2 drops 2-3 times a day. To children from 1 to 6 flyings — 0,025% of a drop on 1-2 drops 2-3 times. To children till 1 year appoint 0,01% drug: the newborn on 1 drop 2-3 times. The bottle of 0,01% of drug has the graduated pipette on which the quantity of drops is noted (1, 2, etc.).

Entering of drug into a nose and in a different way is possible: necessary quantity of drops apply on a wadded turunda and wipe with it a nasal cavity. Drug use duration 3-4 days.

Overdose

Overdose appears narrowing of pupils, vomiting, nausea, temperature increase, tachycardia, oppression of cordial activity, arterial hypertension, a collapse. There can be disturbances of mentality. Treatment consists in a gastric lavage and reception of sorbents.

Interaction

At simultaneous use with antidepressants and blockers of MAO increase of the ABP is noted. At co-administration of other vasoconstrictive drugs the risk of side reactions increases.

Terms of sale

It is released without recipe of the doctor.

Storage conditions

Temperature of storage is up to 25 °C.

Period of validity

3 years.

Nazivin at pregnancy

Nazivin at pregnancy it is possible to apply only after an advantage assessment to the pregnant woman and risk to a fruit. Exceeding of a dose during this period is inadmissible.

Analogs

The drugs having the same active ingredient: Nazol, Nazol Advans, Sanorinchik, Noksprey, Afrin, Nesopin, Fazin. Drugs the analogs having similar effect: Halazolinum, Xylomethazolinum, Dlyanos, Ksimelin.

Zdravzona

  • Nazivin of a drop nasal 0,01% 5mlmerck KGaA
  • Nazivin of a drop nasal 0,025% 10mlmerck KGaA
  • Nazivin of a drop nasal 0,05% 10mlmerck KGaA
  • Nazivin spray of nasal 0,05% 10mlmerck KGaA
  • Nazivin Sensitiv spray nasal 11,25mkg/dose 10mlmerck KGaA

Drugstore of IFC

  • Nazivin of a drop nazaln. 0.025% fl 10 ml, Merckgermaniya
  • Nazivin Sensitiv spray 0,05mgml (22,5mkg/dose) 10 ml, Merckgermaniya
  • Nazivin of a drop nazaln. 0.05% fl 10 ml, Merckgermaniya
  • Nazivin of a drop nazaln. 0.01% fl 5 ml, Merckgermaniya
  • Nazivin Sensitiv spray 0,025mgml (11,25mkg/dose) 10 ml, Merckgermaniya
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Apteka24

  • Nazivin aerosol of nasal 0.05% 10mlnikomed (Austria)
  • Nazivinmerck KGaA (Germany)
  • Nazivinmerck KGaA (Germany)
  • Nazivinmerck KGaA (Germany)

Paniapteka

  • Nazivin of a drop in a nose of 0.01% 5mlnikomed
  • Nazivin sensitiv drops in a nose of 0.01% 5mlmerk Kgaa
  • Nazivin of a drop in a nose of 0.01% 5mlnikomed
  • Nazivin sensitiv drops in a nose of 0.01% 5mlmerk Kgaa
  • Nazivin spray of 0.05% 10mlnikomed

BIOSPHERE

  • Nazivin Sensitiv of 11,25 mkg / dose of 10 ml spray naz.doz.ursapharm Arzneimittel (Germany)
  • Nazivin Sensitiv of 22,5 mkg / dose of 10 ml spray naz.doz.ursapharm Arzneimittel (Germany)
  • Nazivin Sensitiv of 0,01% 5 ml of a drop naz.ursapharm Arzneimittel (Germany)
  • Nazivin of 0,025% 10 ml of a drop naz.merck KGaA (Germany)
  • Nazivin of 0,05% 10 ml spray naz.merck KGaA (Germany)
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Section: From cold
in more detail

Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Nazivin surely consult with the attending physician.