Neyroks

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The description is actual on 01.08.2014

  • Latin name: Neurox
  • ATH code: N07XX
  • Active ingredient: Etilmetilgidroksipiridina succinate (Ethylmethylhydroxypyridine succinate)
  • Producer: CJSC Farmfirma Soteks (Russia)

Structure

As a part of 1 ml of solution for intravenous and intramuscular administration 50 mg of active ingredient of ethylmethylhydroxypyridine of succinate and excipients contain: sodium disulphite — 1 mg; water for injections — to 1 ml.

Release form

  • 1 ampoule (2 ml) on 5, 10, 20 and 50 pieces in cardboard packaging;
  • 1 ampoule (5 ml) on 5, 10 and 20 pieces in cardboard packaging.

Pharmacological action

  • drug protects membranes of cells of a brain (neurons) from any influences (membranoprotektivny action);
  • improves blood circulation in a brain and reduces need of neurons for oxygen (anti-hypoxemic action);
  • exerts the direct activating impact on cerebration (nootropic action);
  • removes feeling of alarm, fear and tension;
  • increases resistance to stress (anksiolitichesky action);
  • suppresses development of spasms (anticonvulsant action).

Pharmacodynamics and pharmacokinetics

Active active ingredient of Neyroks of ethylmethylhydroxypyridine succinate (EMGPS) suppresses toxic action of the free radicals which are formed in the course of a metabolism in a human body and destroying cells and fabrics. It protects membranes (cover) of cells of a brain from any influences, improves their structure and function (including transportation of oxygen and neuromediators – substances by means of which information is transferred in brain cells).

Under the influence of Neyroks concentration in a brain of dopamine which is called pleasure hormone increases. All this leads to increase of resistance to stress and mental capacities, decrease in uneasiness and convulsive readiness. Neyroks makes anti-toxic impact at an acute and chronic drunkenness, at an abstinence syndrome (intoxication developing against a separation from alcohol at patients with an alcoholism) and at overdose of the means influencing the central nervous system.

Duration of action of Neyroks at intramuscular introduction — till 4 o'clock. The maximum concentration in a blood plasma comes in 20 – 40 minutes after introduction. Active ingredient quickly passes from blood vessels into bodies and fabrics and also is quickly removed from an organism with urine, previously being metabolized (decaying on exchange products – metabolites) in a liver.

Indications to Neyroks's use

Indications to Neyroks's use:

  • acute disorders of cerebral circulation, including ischemic strokes;
  • the diseases connected with disturbance of exchange processes in cells of a brain (entsefalopiya);
  • states after the postponed craniocereberal injuries;
  • easy intellectual disturbances against atherosclerosis;
  • alarming states against neurosises and mental diseases;
  • myocardial infarction (as a part of complex treatment).

Indications to Neyroks's use include also a drunkenness, an abstinence syndrome against an alcoholism and acute intoxication antipsychotic medicines (neuroleptics).

Medicine of Neyroks – contraindication for use

Neyroks it is impossible to apply at the following diseases and states:

  • the serious illness which is followed by acute disorders of function of kidneys or a liver (an acute renal and liver failure);
  • pregnancy and feeding of the child breast;
  • hypersensitivity of an organism to drug components;
  • to children of any age.

With care of Neyroks apply at allergic diseases and reactions which the patient had in the past. During treatment it is necessary to be careful when driving the car and performing other works demanding the increased concentration of attention and speed of responses.

Drug of Neyroks — side effects

Against fast administration of drug (especially at intravenous jet administration) emergence of dryness and metal smack in a mouth, inflow of heat, irritation in a throat and feelings of shortage of air is possible. Also allergic reactions are possible.

If to use drug the courses exceeding on duration recommended, then it is impossible to exclude emergence of nausea, the increased gas generation in intestines and intestinal gripes, drowsiness or disturbance of backfilling.

Neyroks, application instruction

Neyroks it is entered intramusculary or intravenously (struyno or kapelno). At drop introduction drug gets divorced physical solution (0,9% chloride sodium). Neyroks's dosages most often are selected individually the doctor taking into account a disease, a condition of the patient and recommendations of the producer.

The application instruction of Neyroks recommends to begin treatment with a daily dose of 50-300 mg. It is better to distribute a dose more than 50 mg on 2 – 3 introductions. Gradually the dose is increased before receiving therapeutic effect. The maximum daily dose — 800 mg. The course of treatment depending on a condition of the patient and a dosage can fluctuate from 5 to 30 days.

Intravenously struyno medicine is entered very slowly within not less than 5 minutes, kapelno — with a speed of 40-60 thaws a minute.

Neyroks's pricks – whether overdose is possible?

At overdose emergence of sleeplessness or, on the contrary, drowsiness is possible. If the drug is administered intravenously, some rise in the arterial pressure (AP) within 90 – 120 minutes after introduction is possible. After this time returns to normal symptoms of the ABP independently, the health is recovered within a day.

At sleeplessness medicines from group of tranquilizers (for example, Diazepam) in the minimum dosage are sometimes appointed.

Neyroks's interaction with other medicines

Neyroks potentiates (strengthens) action of benzodiazepine tranquilizers (for example, Diazepam), antiepileptic (Carbamazepine), protivoparkinsonichesky (Levodopa) medicines and nitrates (Nitroglycerine). Reduces toxic effect of alcohol.

Terms of sale

In a drugstore of Neyroks it is possible to get only according to the recipe of the doctor.

Storage conditions

Ampoules of Neyroks have to be stored in the unavailable to children, dry, protected from light place at a temperature not above 25 °C.

Period of validity

Drug is stored 3 years at observance of the above-stated conditions.

Neyroks's analogs

Analogs are drugs of different medicinal groups which are used for treatment of the same diseases. Neyroks's analogs:

Alcohol and Neyroks

Neyroks reduces toxic effect of alcohol.

Zdravzona

  • Neyroks 50mg/ml solution for injections of 2 ml No. 50 ampulysoteks Farmfirma of closed joint stock company
  • Neyroks 50mg/ml solution for injections of 5 ml No. 5 ampulysoteks Farmfirma of closed joint stock company
  • Neyroks 50mg/ml solution for injections of 2 ml No. 10 ampulysoteks Farmfirma of closed joint stock company

Drugstore of IFC

  • Neyroks solution for in/in and introductions in oil 50mg/ml 5 ml No. 5, Soteks Farmfirm Zaorossiya
  • Neyroks solution for in/in and introductions in oil 50mg/ml 2 ml No. 10, Soteks Farmfirm Zaorossiya
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Apteka24

  • Neyrokson of the tab. of 500 mg No. 20kiyevmedpreparat (Ukraine, Kiev)

Paniapteka

  • Neyrokson for injections 1000mg/4ml ampoules of 4 ml No. 10galichfarm
  • Neyrokson for injections 1000mg/4ml ampoules of 4 ml No. 10galichfarm
  • Neyrokson for injections 1000mg/4ml ampoules of 4 ml No. 10galichfarm
  • Neyrokson for injections 1000mg/4ml ampoules of 4 ml No. 10galichfarm

BIOSPHERE

  • Neyrokson of 100 mg/ml 45 ml No. 1 solution for a peroral primen. in flacon. about the syringe. doses. Galichfarm (Ukraine)
  • Neyrokson of 500 mg / 4 ml No. 10 solution for infection. Galichfarm (Ukraine)
  • Neyroks 50 mg/ml 5 ml No. 5 solution d/in.v/v.v/m.amp. Soteks Farmfirma of closed joint stock company (Russia)
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Section: For a nervous system
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