Nikotinamid

Никотинамид Drug photo

The description is actual on 18.01.2015

  • Latin name: Nicotinamide
  • ATH code: A11HA01
  • Active ingredient: Nikotinamid (Nicotinamide)
  • Producer: Aarti Drugs (India), G. Amphray Laboratories (India), Polysynthesis (Russia), Tianjin Pharmaceutical Co. (China)

Structure

Drug contains active agent nikotinamid.

Release form

Nikotinamid in the form of solution for injections from 1%, 2.5%, 5% and tablets is issued.

Solution for injections is packed into ampoules and packaged in boxes on 10 pieces. Tablets are packaged in planimetric cells on 10 pieces, on 1-3 cells in a pack or plastic banks on 20, 30, 50 pieces.

Pharmacological action

Drug possesses the action helping to fill shortage of PP or B3 vitamin and also antipellagric effect.

Pharmacodynamics and pharmacokinetics

Nikotinamid – what is it?

Vitamin means Nikotinamid has the structure which is brought closer to niacin. RR vitamin also belongs to its synonyms.

This substance is the important component necessary for full course of the oxidation-reduction processes happening in a cell. Also vitamin takes part in a metabolism of fats, amino acids, purines, proteins, tissue respiration and a glycogenolysis. At the same time the expressed vasodilating effect, reddenings and irritations on skin, blood "inflow" is not shown. Besides, drug possesses antipellagric action. Fast absorption and a metabolism is characteristic of Nikotinamid.

Indications to use

Nikotinamid is appointed at hypo - and avitaminosis of RR and high need for it connected with:

  • defective and unbalanced food;
  • malabsorption;
  • fast weight loss;
  • diabetes mellitus;
  • long fever;
  • gastrectomy;
  • diseases of gepatobiliarny area – hepatitises, cirrhosis;
  • hyperthyroidism;
  • persistent infections;
  • gastrointestinal tract diseases;
  • malignant tumors;
  • diseases of oropharyngeal area;
  • long stress;
  • lactation, pregnancy.

Besides, this drug is actively used at treatment of acute alcoholic states and dependence.

Contraindications to use

It is recommended to refrain from the use of this vitamin at:

  • hypersensitivity;
  • peptic ulcer of a stomach and 12-perstny gut.

Care in treatment is demanded by such disturbances as:

Side effects

Use of solution for injections sometimes causes allergic reactions mainly in the form of rashes and a skin itch, stidor breath.

Application instruction of Nikotinamid (Way and dosage)

As the instruction on Nikotinamid reports, this substance can be used for intake, and also for p / to, in oil and in/in introductions. The dosage of drug is appointed individually, considering weight of avitaminosis of RR. As a prophylactic – it agrees the daily requirement established by researches. At the same time vitamins are appointed inside, after food.

Special instructions

Except reception of vitamin means for the purpose of prevention of a hypovitaminosis of RR, it is necessary to adhere to the balanced food, having included the products saturated with this vitamin in a diet. Treat them: yeast, liver, egg yolk, nuts, milk, fish, meat, bean, buckwheat, chicken, crude grain, peanuts, green vegetables, proteinaceous products and so on.

As a result of thermal treatment in milk RR vitamin remains.

Reception of vitamin demands control of function of a liver. To prevent development of fatty dystrophy of a liver it is necessary to add a diet with the products saturated with methionine, to accept drug with methionine or other lipotropic means.

Drug is not used as hypolipidemic means. It is possible to lower an irritant action on mucous membranes of a gastrointestinal tract if to wash down tablets with milk.

Overdose

Reception of high doses of vitamin can lead to development: arrhythmias, dizzinesses, diarrheas, xeroderma and mucous membranes of eyes, hyperglycemia, glucosuria, thirst, hyperuricemia, mialgiya, nausea, vomiting and so on.

Prolonged use of RR vitamin sometimes causes fatty dystrophy of a liver, a cholestasia.

Interaction

The concomitant use of a nikotinamid and Carbamazepine is capable to increase its keeping in composition of blood. Therefore obligatory dose adjustment is required.

Terms of sale

In drugstores vitamin means is released without recipe.

Storage conditions

The dark and dry place unavailable to children will be suitable for storage of drug.

Period of validity

3 years.

Analogs

Coincidence on the ATH code of the 4th level:

Analogs are provided by drugs: Aminicotinum, Benicotum, Endobionum, Niacevitum, Bepella, Niacinamidum, Nicofortum, Nicotolum, Niacin, Nicamidum and Pelminum.

Possess also similar action: Neyrovitan, Folic acid and Bepanten.

Section: Vitamins
PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Nikotinamid surely consult with the attending physician.