Нокспрей Drug photo

The description is actual on 15.12.2015

  • Latin name: Noksprey
  • ATH code: R01AA05
  • Active ingredient: Oxymetazoline (Oxymetazoline)
  • Producer: Sperko Ukraine joint venture (Ukraine)


1 ml of spray includes 500 mkg of oxymetazoline of a hydrochloride.

In addition: racemic camphor, disubstituted sodium phosphate, menthol, a benzalkoniya chloride, eucalyptole, propylene glycol, Trilonum of B, the purified water.

Release form

Noksprey is issued in the form of nasal spray, on 10 ml or 20 ml in the polymeric bottles supplied with the sprayer.

Pharmacological action

Vasopressor, antikongestivny.

Pharmacodynamics and pharmacokinetics

Noksprey treats imidazoline derivatives, is alpha adrenomimetikom and possesses local vasoconstrictive action concerning vessels of a nasal cavity.

At local use of spray in a nasal cavity there is a narrowing of the arterioles which are in her mucous membrane thanks to what exudation decreases, the hyperemia and puffiness, decrease allocations from a nasal cavity, and normal nasal respiration is recovered.

Oxymetazoline also promotes decrease in puffiness of the mucous, enveloping passes Eustachian tube, thereby facilitating a drainage at average otitis and a tubo-otitis (eustachitis).

Additional effects of the essential oils which are a part of spray are expressed in elimination of irritation of a mucous nasal cavity and its protection against excessive drying.

The development of local vasoconstriction happening in mucous a nose and adnexal bosoms is observed after 5-10 minutes after use of spray and, according to the individual answer of a human body, can continue for 10-12 hours.

Indications to use

Noksprey's appointment is shown for:

  • treatments of the acute rhinitises which arose owing to allergic reaction or infections;
  • therapies of a tubo-otitis (eustachitis), sinusitis, average otitis;
  • prevention of the complicated nasal breath and a congestion of a nose at diseases of a catarrhal etiology;
  • simplification of process of carrying out a rinoskopiya and other diagnostic procedures in a nasal cavity.


Noksprey's appointment is contraindicated at:

  • pregnancies;
  • the diagnosed atrophic rhinitis;
  • feeding by a breast;
  • personal hypersensitivity to oxymetazoline and/or other components of HP;
  • aged till 6 years.

Noksprey's use with care is possible at:

Side effects

At the recommended dosing mode occasionally observed:

  • sneezing;
  • itch in a nose;
  • feeling of dryness or burning of internal covers of a nose;
  • forming of a reactive hyperemia.

At repeated uncontrollable use sometimes noted:

Very seldom when using spray fixed forming of reactions of hypersensitivity of difficult character, including a Quincke's edema.

At detection of side effects use of drug it is necessary to stop and see urgently behind consultation a doctor.

Noksprey, application instruction

The instruction on Nokspry assumes injection of contents of a bottle in a nasal cavity. For this purpose it is necessary to unscrew a bottle cap, to serially insert its acute tip into each nasal pass and sharp single pressing a bottle to inject spray into a nostril. During performance of this procedure it is necessary to involve with a force a nose air. It is not necessary to overturn a bottle or to reject the head back.

The mode of dosing recommends to patients to make after 12 years 1-2 injections (6-12 years — 1 injection) twice a day in each nasal pass. Duration of use of Noksprey should be limited 7 days.


At uncontrollable excessive use of Noksprey or his accidental oral administration noted development of arrhythmia, a miosis, nausea/vomiting, a hyperthermia, cyanosis, tachycardia, arterial hypertension, vascular insufficiency, disorders of breath, a fluid lungs, mental disturbances, and also a cardiac standstill.

There are single data on suppression of the TsNS functions with the subsequent coma.

Therapy of such states demands carrying out the treatment based on observed symptoms.


It is necessary to avoid simultaneous use of tricyclic antidepressants and MAO inhibitors.

It is not necessary to use Noksprey in parallel with other vasoconstrictive medical drugs for topical intranasal administration.

Terms of sale

Noksprey's acquisition does not demand presentation of the recipe.

Storage conditions

Bottles with spray can be stored at a temperature up to 25 °C.

Period of validity

It is possible to use spray 3 years from the moment of its production.

Special instructions

For the purpose of the prevention of infectious distribution one bottle with drug is intended for use only by one patient.

It is necessary to avoid long use of antiedematouses as it can lead to lowering of their efficiency, and also to development of various negative phenomena connected with overdose.

Abuse of Noksprey can become the reason of an atrophy of a mucous nasal nasal cavity and cause a reactive hyperemia with parallel medicamentous rhinitis.

It is necessary to avoid hit of contents of a bottle in eyes.



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Section: From cold
in more detail

Education: Graduated from the Vinnytsia national medical university of N. I. Pirogov, pharmaceutical faculty, the higher pharmaceutical education – the specialty "Pharmacist".

Experience: Work in Koneks and Bios-Media pharmacy chains as "Druggist". Work as "Pharmacist" in Avicenna pharmacy chain of the city of Vinnytsia.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Noksprey surely consult with the attending physician.