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In 5 ml (one teaspoon) of a deanol of an atseglumat of 1 g (deanol of 320 mg and acid of atsetilglutaminovy 680 mg). Ksilitol, methylparahydroxybenzoate and propilparagidroksibenzoat, water as excipients.
Solution for intake in bottles on 20, 100 and 200 ml.
Pharmacodynamics and pharmacokinetics
Nootropic drug which active ingredient is close on chemical structure to brain metabolites — glutaminic acid and GAMK. Is a neurometabolic stimulator. Renders the tserebroprotektivny, psychogogic, anti-asthenic, antidepressive and psychoharmonizing action. Improves mood and increases activity. Facilitates processes of assimilation and reproduction of information, improves ability to concentration of attention and training. Has no myorelaxation effect, does not break coordination of movements, does not cause accustoming. In the recommended doses hyper stimulation is not noted. Malotoksichen, does not irritate mucous with a gastrointestinal tract.
Possesses gepatozashchitny properties: lowers the level of transaminases and bilirubin, improves a lipidic and pigmental exchange, normalizes cellular structure of a liver, reduces cirrhosis degree of manifestation. At patients at the same time weakness and drowsiness decreases, the skin itch is eliminated.
Efficiency at schizophrenia with asthenic and adynamic frustration is shown, at astenoapatichesky and neurosis-like frustration. At appointment to children it is effective at asthenic states, an intellectual exhaustion, difficulties of storing and training. At children of advanced age the timoleptichesky effect is noted.
Differs in high bioavailability. After intake in 0,5–1 h the maximum concentration of active ingredient is found in a brain, a little smaller — in a liver, heart and kidneys. It is removed by kidneys. T1/2 — 24 h.
Indications to use
As a part of complex therapy it is applied at:
- distsirkulyatorny encephalopathy;
- asthenic and depressive frustration;
- postinsultny frustration;
- craniocereberal injuries in the period of reconvalescence;
- psychoorganic syndrome;
- alcoholic abstinence syndrome;
- for improvement of memory and attention.
At children it is applied at asthenic states, psychological frustration, after craniocereberal injuries and in complex therapy of mental retardation.
- TsNS infections;
- blood diseases;
- psychotic states;
- age till 10 flyings;
- abnormal liver functions, kidneys;
- pregnancy, feeding by a breast.
- sleep disorders;
- allergic reactions;
- weight reduction;
- elderly people have depressions.
Nooklerin, application instruction (Way and dosage)
In one teaspoon — 1 g of active ingredient. 2–3 times a day are appointed inside the adult according to 1 - 2 h to a spoon, it is better for the first half, not later, than in 4 hours prior to a dream. The single dose makes 2 g (2 spoons), respectively a daily dose — 4-6 g, reception of 10 g a day on doctor's orders is in rare instances possible.
Duration of a course is 2 months, with repetition 2 times a year. Nooklerin to children since 10 is appointed in a daily dose of 0,5-1 h a spoon, and to children since 12 — 1-2 h a spoon.
Overdose is shown by strengthening of collateral manifestations. The gastric lavage is undertaken, sorbents are appointed and the symptomatic treatment is carried out.
Strengthens actions of the means stimulating TsNS.
Terms of sale
According to the recipe.
Temperature is up to 25 °C.
Period of validity
To store the opened bottle no more than a month.
Coincidence on the ATH code of the 4th level:
Advantage of this nootropic drug is that in its basis — natural metabolites. It provides the maximum therapeutic effectiveness and a minimum of side effects. At clinical approbation it is established that it is a little toxic and deprived of negative effects of psychostimulants. Possesses the expressed nootropic and psychogogic activity therefore it is effective at the asthenic and astheno-depressive states arising against somatopathies, infections, reactions to acute stress. At the same time at teenagers efficiency is higher, than at adults.
Drug is recommended for correction of an antipsychotic syndrome, improvement of intellectual functions. With success it is applied in sports medicine to correction of efficiency of athletes as helps to take off fatigue, overfatigue after intensive loadings. Existence at this means of gepatozashchitny properties therefore it is used in treatment of alcoholism with the accompanying damage of a liver and at liver diseases is important. Here some responses of patients.
- "… Drug soft. If not considerable — returns deviations to norm. But you should not wait for strong effects of it".
- "… Drug improves mood when accepted it — with all the heart laughed, of course apropos".
- "… There was an adynamy against anemia. The hematologist, really appointed, felt better".
- "… The effect is, gives the raised state, but you should not wait for miracles".
- "… Eliminates weakness, a fast emotional and physical exhaustion. After monthly reception became not such scattered and memory improved".
- "… Appointed at a puerperal adynamy (I did not nurse). Helped well — there was an activity, desire to live and to do something".
- "… The neuropathologist at chronic fatigue after constant overloads at work recommended. Became concentrated, memory improved, there was a desire to live and create".
From by-effects some patients noted sleeplessness and early awakenings.
However, often meet About external use of this means that it is caused by what drug contains derivative dimethylaminoethanol (DMAE) — a deanol atseglumat. Nooklerin in cosmetology is applied as a source of DMAE of high concentration (6,4%). It, but in smaller concentration is a part of creams and tonics for increase of elasticity of skin and pulling up of a contour, the rejuvenating mesococktail, and also with it the ionophoresis is carried out. In house conditions for the purpose of economy many use pharmaceutical drug.
Nooklerin for the person is recommended to use accurately, at first pointwise to check the sensitivity as reaction in the form of irritations and allergies is possible. In the absence of reaction it is possible to put in the form of a mask for 20 minutes on a face and area of a decollete. It is necessary to remember that DMAE is not combined with Retinolum and acids therefore it is impossible to apply at the same time creams with these ingredients. According to researches DMAE well moistens skin, increases exchange processes in it, protects from free radicals. Here some About use of this drug outwardly.
- "… Gives instant effect of lifting. At regular use outwardly does not allow to grow old, rejuvenates".
- "… Nooklerin from wrinkles pointwise — used where wrinkles or skin lost a tone. Considerably tightens and smoothes".
- "… Skin as if is pulled. The effect remains during the day".
- "... I periodically use as a mask. The effect is pleasant — skin more dense and is fresher".
- "… I 2 times a week did. Initially substance liquid, and when drying on a face lipkovaty".
- "… Applied DMAE of 1%, there was a feeling that skin was pulled. Through time skin of a zadubel and oblezl. So I will not apply any more, especially in such concentration".
Judging by some responses, emergence of pigmentation is possible.
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Drugstore of IFC
Section: For a nervous system
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