Normolakt

Нормолакт Drug photo

The description is actual on 06.07.2016

  • Latin name: Normolact
  • ATH code: A06AD11
  • Active ingredient: Lactulose (Lactulose)
  • Producer: CJSC NPTs "Borshchagovsky Chemical and Pharmaceutical Plant" (Ukraine)

Structure

Lactulose, syrup.

Release form

Syrup — colourless viscous transparent liquid in a glass bottle in cardboard packaging on 100 and 200 ml.

Pharmacological action

Stimulating an intestines peristaltics, laxative, hypoazotemic.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

The main active ingredient of drug lactulose belongs to synthetic derivatives of lactose. In a stomach and a small intestine it is practically not soaked up due to the lack of necessary enzymes. In a large intestine its splitting on low-molecular organic acids happens under the influence of intestinal microflora thereof pH decreases and osmotic pressure increases that stimulates an intestines peristaltics. It is resulted by normalization of a consistence of fecal masses and their volume increases that normalizes process of defecation and function of intestines in general.

Drug stimulates growth of bifidobacteria, at the same time, development of pathological microflora in a large intestine is oppressed and intoxication products of their life activity as bacteria of a large intestine in the presence of lactulose do not decompose amino acid that reduces accumulation of toxic products of decomposition of proteins decreases. Normolakt inhibits growth and development of salmonellas in a large intestine.

Drug does not cause accustoming and does not reduce absorption of vitamins. Effect of drug comes in 1-2 days after its reception that is caused by process duration passing of lactulose through a gastrointestinal tract.

Pharmacokinetics

Lactulose at intake passes in a large intestine where bacteria, glycolytic metabolize it mainly to milk and to a lesser extent to ant and acetic acids. Lactulose components are practically not absorbed in blood, in insignificant quantity is removed through kidneys.

Indications to use

Intoxications of various etiology, locks, a liver failure, hepatic encephalopathy, cirrhosis, an intestinal dysbiosis, a hypercholesterolemia, a hepatic coma, to children at a syndrome of putrefactive dyspepsia, at hemorrhoids for a softening of fecal masses, before a large intestine operation.

Contraindications

High sensitivity to drug, impassability intestinal, a galactosemia.

Side effects

Drug is well transferred by most of patients, in rare instances — weakness, nausea, a headache, a meteorism, increased fatigue, diarrhea, dizziness. At long reception of doses, considerably exceeding therapeutic disturbance of water and electrolytic balance is possible.

Normolakt, application instruction (Way and dosage)

Syrup of Normolakt is accepted inside. The dosage of drug is selected individually. Treatment is begun with higher dose which through 2-3 after achievement of effect is reduced. At treatment of hepatic encephalopathy the dose makes from 30 to 50 ml for two-three times a day.

At locks in the first days of treatment accept 15-45 ml of drug, and then reduce a dose to 10 to 25 ml. In the absence of effect in 2-3 days of reception, an initial dose it is necessary to increase. The daily dose of drug is recommended to be accepted during a breakfast in one step. Normolakt it is possible to mix with food mixes, vegetable and fruit juice.

Normolakt for children about one year measure on a scale on the portioning device, offered with drug. To children of advanced age and adults, it is possible to dose drug spoons (tea — 5 ml), (dessert — 10 ml or the dining room — 5 ml. Effect of drug comes in 1-2 days.

Overdose

In cases of administration of drug in high dosages pains in the area in a stomach, diarrhea can develop.

Interaction

Normolakt it is recommended to accept with an interval not less than 2 hours after reception of other HP. At administration of drug with kishechnorastvorimy HP of rn-dependent, there is a risk of decrease rn intestines. The therapeutic effectiveness of lactulose decreases at a concomitant use with antacids or antibiotics of a wide range.

Terms of sale

Non-prescription dispensing.

Storage conditions

At a temperature of 10 — 25 °C.

Period of validity

2 years.

Normolakt's analogs

Lactulose, Biofloraks, Dufulak, Medulak, Laktuvit, Depuraks, Portalakto Normaza and others.

About Normolakta

About drug in the majority favorable. Patients note its high performance.

  • "… At my grandmother in communication regular locks began slow-moving way of life, and to persuade her to take a pill very difficult. Normolakt's use practically solved this problem. We add it to compote or juice".
  • "… At ours six monthly sons locks began, gave enemas, helped for a while, and then began again. The doctor recommended syrup of Normolakt, the chair in a day appeared and then everything was normalized".

Apteka24

  • Normolakt ml syrup 100 flakonborshchagovsky HFZ (Ukraine, Kiev)
  • Normolakt
Section: Gastrointestinal
in more detail

Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

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