And whether you know...
Ornidazol, microcrystallic cellulose, starch, magnesium stearate, sodium of a kroskarmeloz, Opadry covering orange, water.
Tablets of 500 mg in a cover of orange color, a round form, in the blister, in a cardboard pack No. 10.
Pharmacodynamics and pharmacokinetics
Drug belongs to derivatives 5 nitroimidazoles which active ingredient is DNK-tropnymi properties, possessing antiprotozoan and bactericidal action. Ornidazol is active concerning protozoa (lyambliya, trichomonads, gardnerell, a dysenteric amoeba, leyshmaniye, balantidiya), and also gram-negative and gram-positive bacteria.
Ornidazol after oral administration is quickly and well soaked up from a gastrointestinal tract (about 90%). The maximum concentration in blood can be found in 3 hours. With proteins of plasma communication weak (about 13%). Well gets into all fabrics and liquids of an organism.
The cumulation coefficient at course administration of drug of an ornidazol in a dose of 500 mg or in the 12th hour makes 2,5. The metabolism happens in a liver to education alpha hydroxymethyl and hydroxymethyl of metabolites which have rather low pharmacological activity of rather anaerobic activators and Trіchomonas vagіnalіs, than not changed Ornidazol. It is removed with urine, mainly in the form of metabolites. An elimination half-life — 13 hours.
Indications to use
- Treatment of trichomoniasis, amebiasis (intestinal infections and abenteric forms of an amebiasis), lambliasis;
- Prevention of mephitic gangrenes at operative measures in gynecologic practice.
High sensitivity to drug, TsNS diseases (multiple sclerosis, epilepsy), age till 3 flyings, pregnancy and the period of a lactation.
- nausea, gastrointestinal frustration;
- drowsiness, headache, dizziness, incoordination, tremor, spasms, fatigue, loss of consciousness, neuropathy, hypersensitivity reactions.
Orgil, application instruction (Way and dosage)
Pill Orgil is taken after meal, washing down with water. Schemes of treatment:
- Trichomoniasis: on 1 tablet (500 mg) 2 times a day 5 days or a single dose of 3 tablets (1,5 g) for the night. For achievement of effect it is recommended to enter vaginal tablets in addition. The course of treatment of the sexual partner is obligatory.
- Lambliasis: inside, on 3 tablets a day (1,5 g) 1-2 days.
- Intestinal amebiasis: on 3 tablets (1,5 g) of 1 times a day three days.
- Abenteric amebiasis: on 0,5 g (1 tablet) in 2 times a day 5-10 days.
- Prevention of mephitic gangrenes: before an operative measure 2 times a day on 1-2 tablets (0,5 - 1 g) 3-4 days.
Depression, spasms, neuritis peripheral.
Drug strengthens effect of anticoagulants of a coumarinic row, exponentiates myorelaxation effect a bromide vekuroniya. At a concomitant use with other drugs — derivatives 5 nitroimidazoles — increase risk of development of a neuropathy, spasms as epilepsy, a depression.
Ornidazol does not interact with alcohol. Simultaneous reception with barbiturates, rifampicin reduces time of half-decay of an ornidazol. It is not recommended to accept drug with gematoksichny and neurotoxic HP.
Terms of sale
At a temperature up to 25 °C.
Period of validity
About drug favorable. Patients note that Orgil's use in complex treatment of infections of the urogenital sphere allows to recover completely.
/a class='other-apteks-link link03'>to show still
PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Orgil surely consult with the attending physician.
img src="//medicalmed.us/img/Veroshpilakton-110x80.jpg" tppabs="medicalmed.us/wp-content/uploads/2016/07/Veroshpilakton-110x80.jpg" width="110" height="80" alt="" /> About Veroshpilaktona