Ornidazol-Vero

Орнидазол-Веро Drug photo

The description is actual on 06.05.2014

  • Latin name: Ornidazole-Vero
  • ATH code: G01AF06
  • Active ingredient: Ornidazol (Ornidazole)
  • Producer: JSC VEROFARM, Russia

Structure

Structure of one tablet of drug:

  • ornidazol;
  • MKTs, corn starch, sodium carboxymethylstarch, PVP, magnesium stearate.

The cover consists of the following components: PVP, titanium dioxide, twin-80, oksipropilmetiltsellyuloza, talc.

Release form

Medicine of Ornidazol-Vero is issued in the form of round white tablets which are covered with a film cover. In cardboard packaging there is a blister containing 10 tablets.

Pharmacological action

Has antiprotozoan effect.

Pharmacodynamics and pharmacokinetics

Ornidazol-Vero – the drug which is rendering antiprotozoan effect, and also possessing antibacterial activity. 5 nitrogroups of an ornidazol which then interacts with cellular DNA work by recovery, reducing synthesis of acids therefore bacteria perish.

It is active against: Giardia intestinalis, Gardnerella vaginalis, Trichomonas vaginalis, Histolytica Entamoeba. Also drug is capable to resist to obligate anaerobic organisms (Bacteroides spp., Fusobacterium spp., Prevotella spp., Veillonela spp.) and to gram-positive microorganisms (to Clostridium spp., Clostridium spp.).

It is not effective against aerobic microorganisms.

Bioavailability at the level of 90% is easily soaked up from a gastrointestinal tract. Reaches the maximum concentration in 1,5-2 hours. 60% are brought with urine, 21% — with a stake in the form of metabolites, in an invariable look about 5% are brought.

Indications to Ornidazol-Vero's use

Medicine is appointed in the following cases:

  • lambliasis;
  • amoebic dysentery;
  • amebiasis (including abenteric);
  • trichomoniasis;
  • prevention of infections which can result from action of anaerobic bacteria;
  • in gynecology;
  • at operative measures on a colon.

Contraindications

Drug is contraindicated to use at TsNS diseases. Also it is not recommended to use it during the I trimester of pregnancy, feeding by a breast and at sensitivity to any of medicine components (including nitroimidazole derivatives).

Side effects

Treatment by this medicine can cause the following side effects:

  • dizziness, diskoordination of movements, disturbance of consciousness, spasm, rigidity, headache, tremor, peripheral neuropathy;
  • nausea, diarrhea, vomiting.

Application instruction of Ornidazol-Vero (Way and dosage)

It is necessary to accept Ornidazol-Vero inside, right after meal.

At trichomoniasis children should accept a dose in the amount of 0,25 g on each kg of weight once; the adult – twice a day on 0,5 g. For adults a course of treatment – 5 days.

At amoebic dysentery adults and children (weighing more than 35 kg) have to accept a day 1,5 g, weighing more than 60 kg – 2 g. Children, whose weight less than 35 kg take medicine on 40 mg on 1 kg of weight. It is necessary to continue treatment 3 days.

In the presence of other forms of an amebiasis adults and children (weighing more than 35 kg) have to accept twice a day 0,5 g, weighing less than 35 kg – 25 mg on 1 kg of weight (once). It is necessary to continue treatment from 5 to 10 days.

At a lambliasis to children (weighing more than 35 kg) and adult appoint a day 1,5 g, weighing less than 35 kg – 40 mg to each kg of weight. It is necessary to continue treatment 2 days.

To prevent complications which can be caused by bacteria anaerobic after operation, it is necessary to accept 0,5 g before operation, then during the period at 4-5 in the afternoon each 12 hours to take medicine on 0,5 g.

Overdose

Overdose symptoms: depression, epileptiform spasms, peripheral neuritis. At emergence of these symptoms carry out a symptomatic treatment.

Interaction

Ornidazol-Vero's drug is capable to strengthen effect of anticoagulants of a kumirinovy row, to increase effect a bromide vekuroniya.

At combined use with ethanol Ornidazol does not inhibit an atsetaldegiddegidrogenaza.

Terms of sale

According to the recipe.

Storage conditions

It is necessary to store in the place protected from penetration of light and moisture, average temperature about 25 degrees Celsius.

Period of validity

It is recommended to store no more than 2 years.

Special instructions

It is necessary to appoint a course of treatment for both sexual partners at trichomoniasis.

Responses on Ornidazol-Vero

Many patients in the responses write about weak efficiency of drug and is strong manifestation of side effects.

Zdravzona

  • Ornidazol-Vero of 500 mg No. 10 tabletkiverofarm joint stock company

Drugstore of IFC

  • Ornidazol-vero tbl p / about 500 mg No. 10, Veropharm / the Voronezh branch (Voronezh) Russia
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Section: Antibiotics Gynecologic
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