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1 capsule contains 200 mg or 300 mg of Gopantenovy acid (D, L) – active agent.
Auxiliary ingredients according to the mass content of active agent:
- 1,02 mg or 1,53 mg — stearate magnesium;
- 13,98 mg or 20,97 mg — cellulose microcrystallic.
- titanium dioxide;
- sodium lauryl sulfate;
- the water purified.
Medicine Pantogamum an asset is issued in the form of capsules on 200 mg or 300 mg.
One packaging may contain 30, 50 or 60 capsules.
Pharmacodynamics and pharmacokinetics
Pantogamum an asset, in the structure, contains the piperidic acid (GAMK) which is directly influencing on GAMKB - a receptor and channel complex. Drug is racemic mix of equivalent shares of Gopantenovy acid in a R-form and its S-isomer thanks to which transportation and interaction of medicine with GAMK receptors improves. The drug Pantogamum an asset shows more expressed anticonvulsant and nootropic action, than the medicines of the first generation containing Gopantenovuyu acid.
Pantogamum an asset increases resistance of a brain to a lack of oxygen (hypoxia), and also to influence of the substances poisoning him, activates anabolic processes in brain neurons, combines a soft promoting effect with moderate sedation. Shows easy antialarming and anti-asthenic activity. Reduces motor excitability, activates physical and cerebration, the behavior arranges. Interferes with pathological increase of a vesical reflex, and also disturbance of a tone of a detruzor.
At oral administration active agent of Pantogamum the asset is quickly soaked up from a gastrointestinal tract.
Possesses ability to get through GEB.
It is not metabolized and for 48 hours it is removed in not changed look by kidneys — about 70% and intestines — about 30%, the dose accepted earlier.
Indications to use
- epilepsy (with parallel reception of anticonvulsant drugs);
- cerebrovascular insufficiency, because of atherosclerotic pathologies of vessels of a brain;
- the cognitive disturbances at neurotic frustration and also caused by organic lesions of a brain (including effects of craniocereberal injuries and neuroinfections);
- extrapyramidal hyperkinesias (Parkinson's illness, a chorea of Gentington, a myoclonus epilepsy, a hepatolenticular degeneration and so forth), therapy of an extrapyramidal syndrome which was caused by use of neuroleptics;
- lowering of physical and intellectual activity, psychoemotional overloads, for the purpose of improvement of memory and concentration of attention;
- schizophrenia (it is applied as a part of complex treatment);
- neurogenic disturbances of an urination (enuresis, a pollakiuria, an imperative mochenederzhaniye, imperative desires to an urination).
- hypersensitivity to Gopantenovy acid or other ingredients of capsules;
- heavy or acute pathologists of kidneys;
- period of chest feeding;
- first trimester of pregnancy;
- age of the patient till 18 flyings (because of lack of clinical trials on influence of Pantogamum an asset at earlier age).
Application instruction Pantogamum asset (Way and dosage)
Medicine Pantogamum an asset is intended for oral (internal) administration. As a rule, drug is accepted in 15–20 minutes after meal, by 2 or 3 times a day. The recommended time of inclusion in a morning or day time.
The usual mode of dosing of capsules on 200 mg makes — 0,2–0,8 g (1–4 capsules) a day.
Capsules on 300 mg — 0,3–0,9 g (1–3 capsules) a day.
The most admissible daily dose of Pantogamum an asset equals — 2,4 g (12 capsules on 200 mg or 8 capsules on 300 mg).
The course of therapy lasts from 30 days to 4 months, in certain cases treatment is continued for 6–12 months. After 3–6 months it is possible to conduct a repeated course of therapy.
At overdose by the drug Pantogamum an asset strengthening of symptoms of its side effects is possible.
The gastric lavage, reception of enterosorbents, carrying out symptomatic therapy is shown.
Pantogamum an asset strengthens effect of anticonvulsant medicines.
At combined use with barbiturates prolongs their action.
Warns side effects of Carbamazepine, Phenobarbital, neuroleptics.
The combined reception of Etidronovy acid and Glycine strengthens action of Pantogamum an asset.
Terms of sale
According to the recipe.
At a temperature not above 25 °C.
Period of validity
At drug Pantogamum use an asset throughout a long span, the concomitant use of other medicines with the stimulating TsNS and nootropic action, is not recommended.
Coincidence on the ATH code of the 4th level:
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Drugstore of IFC
Section: For a nervous system
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