Перметрин Constitutional formula

The description is actual on 15.10.2015

  • Latin name: Permethrinum
  • ATH code: P03AC04
  • Chemical formula: C21H20Cl2O3
  • CAS code: 52645-53-1

Chemical name

3-Fenoksibenzilovy ether 3-(2,2-dikhloretenit)-2,2-dimethylcyclopropanecarboxylic acid

Chemical properties

Permethrin is carried to group of pyrethrins. Substance is on sale in the form of yellow, brown-orange solid substance or viscous liquid. In a firm aggregate state means easily melts.

Medicine is let out in the form of lotions for local use, creams or emulsions.

Pharmacological action

Insecticidal, protivopedikulezny, acaricidal.

Pharmacodynamics and pharmacokinetics

Medicine breaks ion permeability of natrium channels, slows down processes of repolarization of membranes of nervous cells of ekzoparazit that leads to their paralysis and death. Means is effective in relation to louses, fleas, mites, itch mites, we designate to arthropods.

At local use at most 2% of substance get into a system blood stream. In an organism means is exposed to hydrolysis and turns into inactive metabolites which then are removed them an organism by means of kidneys.

After single application the protivopedikulezny effect remains from 2 weeks to 1,5 months (depends on what dosage form to use).

Indications to use

Sufficient efficiency Permethrin from mites, fleas, louses, nits possesses. Substance is applied to disposal of a demodicosis, a pediculosis and itch.


Permethrin cannot be used:

  • if the patient has an allergy to active this agent, other synthetic pyrethroids, plants containing pyrethrins;
  • for treatment of itch at the feeding women;
  • aged till one year (emulsion);
  • to the children who did not reach age of 6 months (cream).

During therapy it is recommended to be careful:

  • to pregnant women;
  • to children till 5 flyings;
  • at the accompanying skin diseases.

Side effects

During treatment the following side reactions can be observed by drug:

  • burning and pricking in a means site of application;
  • numbness of skin, itch, tingling;
  • skin allergic reactions, hypostases, erythema.

Application instruction (Way and dosage)

Drugs on the basis of means use exclusively outwardly.

The instruction on Permethrin cream of 0,5% and lotion of 1% of louses

Medicine with a cotton plug is applied on the struck surface, evenly distributed. It is the best of all to use drug on previously moistened hair. Means can be rubbed in head skin and to cover with a kerchief.

1% leave cream on hair for 10 minutes, lotion needs to be held till 40 minutes. After carrying out procedure drug is well washed away warm water, using soap or shampoo, and dry up.

Further it is necessary to take a fine-tooth comb and with its help to remove the died louses and nits from the processed surface.

If within a week symptoms of a disease are observed and live nits are found, then procedure is recommended to be repeated. As prevention after each washing of the head it is possible to wipe or moisten affected areas with medicine, without washing away.

The instruction on Permethrin at a mange

For treatment of damages of skin for itch mites use 0,4% a water emulsion. Means is rubbed in skin of hands, a trunk and the lower extremities before going to bed.

Treatment duration – 3 days. It is impossible to process solution a face, a neck and head hair. For the 4th day the patient has to take a shower and completely change all next-to-skin and bed linen.


At local use overdose is improbable. If substance accidentally got into a digestive tract, it is necessary to wash out a stomach and to carry out symptomatic therapy.


Medicinal interaction at topical administration is not described and probably does not happen. Before an initiation of treatment it is recommended to consult with the doctor.

Special instructions

During putting drug it is necessary to avoid hit of substance in an oral cavity, on external genitals, mucous membranes, in a nose. If medicine accidentally got on an undesirable body part, it needs to be washed out well water.

If Permethrin from mites caused an allergy, treatment needs to be interrupted and replaced medicine.

The medical personnel during processing of patients have to are in rubber gloves. After carrying out procedure it is necessary to wash up well hands with soap use, to rinse a mouth water.

If after passing of a rate of drug from itch within a month disease symptoms are observed, it is recommended to consult with the attending physician.

In order to avoid infection of family members it is recommended to process clothes and bedding. The linen can be presoaked in a water emulsion for 40 minutes.

Drugs in which contains (Analogues)

Coincidence on the ATH code of the 4th level:

Nittifor, Medifoks, NOC, Niks, Couple plus, Permethrin of Farm, Pedilin, Pervit.

About Permethrin

On the Internet write generally good About Permethrin of Farm. Medicine has no pungent specific smell, is easily applied on hair, rather effectively. Costs rather not much. Also are available positive About spray Permethrin and other means with this active ingredient.

The Permethrin price where to buy

To buy Permethrin as a part of drug of Medifoks, 5% will cost about 130 rubles for a bottle, with a capacity of 24 ml. The Permethrin price in the form of 1% of cream for outwardly use of Niks makes about 380 rubles for a bottle, 59 ml.

Section: Active ingredients
PAY ATTENTION! Information on active ingredients on the website is help generalizing, collected from public sources and can form the basis for making decision on use of these substances it is not aware of treatment. Before substance Permethrin use surely consult with the attending physician.