Pyridoxine

Пиридоксин Drug photo

The description is actual on 11.12.2014

  • Latin name: Pyridoxine
  • ATH code: A11HA02
  • Active ingredient: Pyridoxine (Pyridoxine)
  • Producer: JSC Verofarm, Russia.

Structure

One ampoule of solution for injections contains active component: a pyridoxine a hydrochloride on 10 or 50 mg.

Additional substance: water for injections.

The tablet includes in the structure 2, 5 or 10 mg of a pyridoxine a hydrochloride.

Release form

Pyridoxine the hydrochloride in the form of solution for injections is packaged in ampoules on 1 ml, on 10 ampoules in a box.

Tablets are packed in bank on 50 pieces.

Pharmacological action

Drug possesses the action filling shortage of B6 vitamin.

Pharmacodynamics and pharmacokinetics

It is known that B6 vitamin is an irreplaceable participant of exchange processes, normalizes and supports activity of a nervous system. The Fosforilirovanny form of a pyridoxine represents a coenzyme of considerable number of enzymes which influence not oxidizing exchange of amino acids, for example, decarboxylation or transamination. This component is necessary for exchange processes of tryptophane, cysteine, glutaminic, methionine and other amino acids. It is important and for a histamine exchange, and for normalization of a lipidic exchange.

The metabolism of the main substance occurs in a liver therefore active metabolites are formed pharmacological: pyridoxal phosphate and piridoksaminofosfat. Components generally in muscular tissue, and also in a liver and a nervous system are distributed. Penetration of drug into breast milk and through a placenta is noted. Substance is removed with kidneys, part – with bile.

Indications to use

Drug is used for treatment and prevention of deficit of B6 vitamin at:

Contraindications to use

It is not recommended to accept drug at sensitivity or intolerance of the Pyridoxine.

Special instructions

It is required to show care at purpose of this drug to the patients suffering from a peptic ulcer of a stomach and a 12-pyorstny gut, heart ischemia.

Reception of high doses of a pyridoxine at severe damages of a liver can worsen its work.

Side effects

During treatment development of allergic reactions, hypersecretions of hydrochloric acid is possible.

Application instruction of the Pyridoxine (Way and dosage)

The application instruction recommends to take the pill Pyridoxine inside for the purpose of treatment of a hypovitaminosis. For adult patients the dose on 80 mg, to reception 4 times a day is appointed.

Vitamins B ampoules, as well as Piridoksin-Vial, the application instruction specifies to use 50-150 mg in a daily dosage. Hypodermic, intramuscular or intravenous administration is allowed. Duration of therapy is determined by weight and a type of disturbance. At prevention of a lack of B6 vitamin in days about 40 mg are appointed.

Overdose

In clinical practice of cases of overdose it is not established.

Interaction

Simultaneous use with an isoniazid, Cycloserinum, Penicillaminum reduces efficiency of a pyridoxine. Pharmaceutical incompatibility of B6 vitamin with B1 and B12 is noted. This drug considerably lowers protivoparkinsonichesky activity of a levodopa.

The combination to hormonal contraceptives is capable to increase concentration of a pyridoxine as a part of a blood plasma. Use with Phenytoinum and phenobarbital can reduce concentration as a part of a blood plasma of these components.

Terms of sale

Issue of drug without recipe is allowed, but independently it should not be applied.

Storage conditions

Medicine needs to be stored in the dry, dark, cool place protected from children.

Period of validity

3 years.

Analogs

The pyridoxine is such vitamin which is included in structure of a set of the combined drugs, for example: Magne Vb, Perneksin elixir, Gepasteril-A, Gepasteril-B, Lipostabil, Essentiale.

Analogs of drug are: B6 vitamin, Piridobene, Piradoksin, Vitamin B6, Becilanum, Pyrivitolum, Bedoxinum, Benadonum, Geksabetalin, Geksabion, Hexavibexum and others.

The combination Benphothiaminum + the Pyridoxine represents fat-soluble analog of B1 vitamin or thiamin. Such combination normalizes functions of a nervous system, taking part in carbohydrate metabolism, filling shortage of B1 vitamin.

Zdravzona

  • Piridoksin-vial 5% solution for injections of 1 ml No. 10 of an ampulysa of Es Pi Xi of Oui of Pharmaceutical To. Ltd.
  • Pyridoxine hydrochloride of 10 mg No. 50 tabletkiozon Ltd company
  • Blagomin B6 Vitamin (pyridoxine) No. 90 kapsulyvis Ltd company
  • Pyridoxine a hydrochloride of 5% solution for injections of 1 ml No. 10 ampulybiosintez joint stock company

Drugstore of IFC

  • Pyridoxine of / hl / B6/Vitamin solution for in 5% 1 ml No. 10, Vial of Ltd company / Siespisi Oui Farmasyyutikalkitay
  • Pyridoxine of / hl / B6/Vitamin tbl 10 mg No. 50, Veropharm / Voronezh branch (Voronezh) Russia
to show still

Apteka24

  • Piridoksinzdorovye (Ukraine, Kharkiv)
  • Piridoksindarnitsa (Ukraine, Kiev)
  • Pyridoxine solution for in 50mg/ml amp. 1 ml No. 10lekhim-Kharkiv (Ukraine, Kharkiv)

Paniapteka

  • Pyridoxine of / x solution for infection. 5% of amp. 1 ml No. 10 Health
  • Pyridoxine of / x solution for infection. 5% of amp. 1 ml No. 10 Health

BIOSPHERE

  • Pyridoxine a hydrochloride of 50 mg/ml No. 10 solution for in.amp. JSC Novosibkhimfarm (Russia)
  • Pyridoxine a hydrochloride of 5%/1 ml No. 10 solution for in.amp. Borisovsky ZMP (Belarus)
  • Pyridoxine a hydrochloride of 5%/1 ml No. 10 solution for in.amp.
to show still
Section: Vitamins
PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use the Pyridoxine surely consult with the attending physician.