Povidone

Повидон Constitutional formula

The description is actual on 23.02.2016

  • Latin name: Povidonum
  • ATH code: A07BC03, B05AA
  • Chemical formula: (C6H9NO) of n
  • CAS code: 25249-54-1

Chemical name

1 - etenilpirrolidin - 2 - it

Chemical properties

Povidone — what is it? This substance represents an insoluble form of low-molecular polyvinylpirrolidone with cross bonds. The molecular mass of a chemical compound makes from 12600 grams on mol (an error, depending on length of a chain of 2700 on mol). Medicine is used for a detoxication, as adsorbent. Drugs on the basis of Povidone are used orally. Powder most often has a slight specific smell, white or yellowish color.

Also there is a low-molecular form of substance, with a molecular weight from 6000 to 10000 grams on mol. It is applied as a part of solutions to infusion and desintoxication.

Pharmacological action

Disintoxication, absorbing.

Pharmacodynamics and pharmacokinetics

Povidone has ability to form complexes with various toxic substances and it is safe to bring them out of an organism through intestines. Medicine does not damage and does not interact with a mucous membrane of a stomach and intestines, does not possess ability to collect in an organism.

Substance is not exposed to system absorption, is removed with a fecal masses. The effect after reception of powder develops within 15 minutes – half an hour. Under the influence of drug speed decreases and extent of absorption of toxins in blood decreases. Means also slows down absorption of other drugs and useful components of food.

Indications to use

Drug is appointed:

  • at a burn disease in intoxication phase;
  • for treatment of toxic forms of acute infectious gastrointestinal diseases (salmonellosis, dysentery);
  • at a radial illness (intoxication phase);
  • for elimination of intoxications during the postoperative period;
  • at toxicosis of pregnant women;
  • to patients with a hemolitic illness, sepsis and a toxaemia of newborns;
  • at food toxicoinfection;
  • during aggravations of chronic coloenterites and enterit;
  • at a chronic liver failure.

Contraindications

Povidone cannot be used:

  • for treatment of the patients sick with bronchial asthma;
  • at acute nephrite;
  • at patients with a hematencephalon;
  • at heavy cardiovascular insufficiency;
  • if the patient has an allergy to this substance.

Side effects

Usually drug is transferred well.

In rare instances can be observed:

  • lowering of the ABP, tachycardia;
  • suddenly arising and quickly passing nausea and vomiting;
  • the heavy, complicated breath.

Povidone, application instruction (Way and dosage)

Depending on a disease and its weight use different amount of drug.

Medicine is appointed inside. In 2 hours after meal or other drugs.

In a suspension preparation time for intake it is recommended to adhere to the recommendation in the instruction. It is possible to add sugar or juice to solution.

Children aged from 1 year can give 300 ml on weight kg a day. To children from 3 to 6 years appoint 150 ml of suspension, distributing on 3 receptions. At the age of 7-10 it is possible to use up to 200 ml of solution within a day. Of 11 flyings appoint 300 ml of suspension a day, for 3 receptions. For adults the daily dosage can be calculated, depending on weight.

The course of treatment is defined by the doctor.

Overdose

At acute overdose side effects from medicine can amplify.

Interaction

At a drug combination to other drugs for intake speed can be slowed down considerably and decrease extent of absorption of active components from a digestive tract.

Terms of sale

The recipe is not required.

Storage conditions

It is important to store povidone in the form of powder for preparation of suspension in the dry, dark place. It is also necessary to observe particular temperature condition – from-10 to 30 degrees Celsius. Medicine needs to be protected from small children.

Special instructions

If during treatment the patient had any unusual reactions to drug, then therapy needs to be interrupted, in addition to appoint a symptomatic treatment.

This substance is contraindicated to reception by patients with acute nephrite.

At pregnancy and a lactation

Means can be appointed during pregnancy and when feeding a breast by the attending physician according to indications.

Drugs in which contains (Analogues)

Synonym of medicine is the drug Enterodesum. Also this component in the form of low-molecular Povidone contains in solution for infusions Haemodesum-8000, Haemodesum – N, Glyukoneodez, Krasgemodez 8000 Povidone, Neogemodez, Oftolik, Oftolik BK.

Section: Active ingredients
PAY ATTENTION! Information on active ingredients on the website is help generalizing, collected from public sources and can form the basis for making decision on use of these substances it is not aware of treatment. Before substance Povidone use surely consult with the attending physician.