Превенар Drug photo

The description is actual on 20.09.2014

  • Latin name: Prevenar and Prevenar 13
  • ATH code: J07AL02
  • Active ingredient: Polysaccharides of several serotypes and CRM197 carrier protein.
  • Producer: Prevenar – Wyet Pharmaceutical Division of Wyeth Holdings Corporation, the USA Prevenar 13 – Petrovax Pharm of NMTs of Ltd company, Russia


As a part of Prevenar pneumococcal conjugates, that is polysaccharides of serotypes contain: 4, 6V, 9V, 14, 18S, 19F, 23F and CRM197 carrier protein.

The general enter a vaccine Prevenar 13 Prevenar seven serotypes, and also CRM197 carrier protein.

Generally, this drug includes kapsulyarny polysaccharides of 13 serotypes of a pneumococcus: 1, 3, 4, 5, 6A, 6V, 7F, 9V, 14, 18S, 19A, 19F and 23F, individually conjugated with diphtheritic CRM protein ₁₉₇ and adsorbed on aluminum phosphate.

Auxiliary components: aluminum phosphate, succinic acid, sodium chloride, polysorbate and water for injections.

Release form

The vaccine in the form of the suspension of white color intended for introduction in oil, homogeneous is issued. Formation of a white muddy deposit is possible. Drug is placed in one-time syringes, on 1 or 5 pieces in packaging.

Pharmacological action

Vaccine for prevention of pneumococcal infections.

Pharmacodynamics and pharmacokinetics

Vaccines for prevention of pneumococcal infections contain the active agents which are pneumococcal polysaccharides, received from the gram-positive bacteria of Streptococcus pneumoniae conjugated with diphtheritic CRM197 carrier protein, and adsorbed on aluminum phosphate.

At administration of drug development of antibodies to kapsulyarny Streptococcus pneumoniae polysaccharides of several serotypes begins that allows to provide specific protection of a human body against infections which they cause.

Immunological efficiency

Use of a vaccine for children with 2kh allows to create months a protective immune response after carrying out primary immunization and a revaccination. Introduction 3 doses of primary immunization, and then the subsequent revaccination promotes considerable rise in level of antibodies. Drug induces development of functional antibodies to the serotypes making a vaccine.

At little patients 2-5-year-old children of age of an antibody to serotypes of a vaccine are formed after single use. At the same time the immune response almost corresponds to results of inspection of the children who received a series of primary immunization.

Besides, the inoculation Prevenar 13 is entered for prevention of infectious diseases, pneumonia and acute average otitis.

Comparative identity of these vaccines on a profile of safety and an immunogenicity also allows to pass from Prevenar on Prevenar 13 practically at any stage of vaccination. At the same time 6 additional serotypes will only strengthen protection against IPI.

Indications to use

This vaccine is intended for prevention of diseases which cause Streptococcus pneumoniae the serotypes which are a part of drug and also:

Contraindications to use

It is not recommended to carry out vaccination at:

  • hypersensitivity to components of a vaccine and a diphtherial anatoxin;
  • acute infectious and noninfectious diseases;
  • exacerbations of chronic diseases.

Side effects

Vaccination by Prevenar or Prevenar 13 can lead to development of the general and local reactions: to reddening, puffiness, morbidity or consolidation in an injection site, a hyperthermia more than 38 °C, irritability, drowsiness, problems with a dream.

Disturbances of activity of the hemopoietic, lymphatic, immune, nervous systems and gastrointestinal tract are also possible: regional limfoadenopatiya, reactions of hypersensitivity, spasm, vomiting, diarrhea, appetite loss and so on.

Application instruction Prevenar (Way and dosage)

The vaccine is intended strictly for intramuscular introduction in perednebokovy area on a hip surface – to kids till 2 years, and in a deltoid muscle of a shoulder, for example, for children of 2 years. The one-time dosage makes 0,5 ml.

Before introduction the syringe with a vaccine is carefully stirred up, before formation of homogeneous suspension. Use of drug with foreign debris or with the changed color is forbidden.

As the instruction on Prevenar 13 reports and Prevenar, these vaccines are not intended for intravenous administration.

For children of different age from 2 months to 5 years certain schemes of vaccination by Prevenar are established.

At the age of 2-6 months a series of 3-fold primary immunization, bucketed is carried out not less than a month. It is also possible to carry out 2-fold primary immunization with an interval of 2 months. Introduction of the first dose in 2 months of life is possible. The revaccination is carried out once at the age of 11-15 months. Such scheme is suitable for individual immunization of children from a pneumococcal infection.

If vaccination to 6 months of life was not carried out, then use of the following schemes is allowed:

  • Age of 7-11 months – carry out 2-fold vaccination with an interval of 1 month. A single revaccination on the 2nd year of life.
  • 12-23 months – 2-fold vaccination with an interval of 2 months.
  • 2-5 years – once.

When at first Prevenar is entered, Prevenar's use 13 is allowed further. However vaccination by Prevenar 13 can come to an end only with this drug. If it is forced was the interval between injections of any vaccine is increased, then introduction of additional dosages is not required.


Cases of overdose by Prevenar are improbable as the vaccine is issued in the syringe which contains one dose.


Prevenar's introduction along with other vaccines which are included in the National calendar of preventive inoculations, except BTsZh is allowed. According to the coordinated scheme of immunization the combination to a hexavalent vaccine of Infanriks or an inoculation against Hib is possible. At the same time injections shall be made in various body parts.

Special instructions

The vaccine Prevenar is not used for adult patients.

It is recommended to postpone introduction if there is an acute disease accompanied both with the moderated, and expressed hyperthermia. To avoid development of any reactions, after an inoculation within 30 minutes the kid needs to be under control of the specialist. In the rest of the time, being in house conditions, it is necessary to watch the general condition of the child to parents.

It is established that the advantage of a vaktsinatsinirovaniye of this group of patients is highest therefore it is not necessary to refuse or postpone from it date. However it is necessary to remember that Prevenar does not protect from serotypes of Streptococcus pneumoniae which are not available in its structure and from the microorganisms causing other invasive diseases.

Vaccination by Prevenar is not appointed to the children having the thrombocytopenia and other disturbances connected with coagulability of blood. To such patients do not appoint intramuscular injections. An exception are cases when the potential advantage of an inoculation considerably exceeds risk which causes introduction of a vaccine.

Existence of disturbances of an immunoreactivity because of immunodepressive treatment of HIV infection and so on, can lower antibody formation as the response to vaccination. In general the decision on vaccination of the children belonging to various groups of high risk is recommended to be accepted individually.

Let out Prevenar in the syringe, ready to use, therefore its contents are not recommended to be placed in other capacity or to mix with any medicines.

Terms of sale

Drug is released strictly according to the recipe

Storage conditions

Prevenar it is necessary to store at 2-8 °C, without freezing, in the place unavailable to children.

Period of validity

3 years.

The main analogs of this drug are: A vaccine for prevention of hepatitis B and Pneumo 23.

Prevenar 13 or Pneumo 23 — what is better?
Many parents show willingness to provaktsinirovat the child from pnemokokkovy infections, but do not know what vaccine to choose: Prevenar 13 or Pneumo 23? Specialists recommend to make a choice in advantage Prevenar 13 though in it both the smaller quantity of serotypes, but as this drug creates immunity better, and efficiency is higher than it.

About Prevenar

It should be noted that an inoculation Prevenar About which meet in a large number at various forums, causes many disputes and doubts. Of course, for many parents similar prevention seems very attractive, but some them them are not sure of its efficiency at all. Moreover, quite often users consider such inoculations as the reason of development of side effects and even mortality among kids.

Also in a network it is possible to meet comments of doctors on Prevenare. The opinion of specialists on this vaccine is very various. If one describe positive takes of vaccination, then others point to certain facts, for example, that serotypes 1 and 5 which generally and cause pneumococcal infections are not a part of drug. Besides, it is reported that this vaccine is temporarily prohibited in some countries, for example, in the Netherlands.

Quite often users tell that on carrying out vaccination they are persuaded in private clinics. At the same time messages on development of side effects in the form of fervescence sometimes meet. Generally About Prevenar 13 contain information that vaccination takes place successfully, without development of undesirable manifestations. Parents tell that they strictly adhered to all recommendations of doctors and always maintained the established interval between inoculations. After that children are ill less, and they quietly attend kindergarten and other public places.

Prevenar's price where to buy

The vaccine Prevenar can be bought at cost from 2600 rubles. The price Prevenar 13 makes 2160-2500 rubles.

Drugstore of IFC

  • Prevenar13 a vaccine for prevention pneumococcal inf-y 0,5ml, Petrovax Pharm of NMTs of Ooorossiya
to show still
Section: Immunity increase Antiviral
PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Prevenar surely consult with the attending physician.
Application instruction of the Nurofen of the Lady
Korizaliya at pregnancy
The instruction on Sulfur iodine 6
Price of Fosfalyugel's analogs