Презартан Drug photo

The description is actual on 13.07.2016

  • Latin name: Presartan
  • ATH code: C09CA01
  • Active ingredient: Lozartan (Losartan)
  • Producer: Ipca Laboratories (India)


Lozartan of potassium, the dried-up starch, microcrystallic cellulose, silicon dioxide, sodium of starch glikolit, magnesium stearate, a methylene the chloride, talc purified isopropanol, dye red.

Release form

Mg tablets 25 and 50 in a film cover of a round form, biconvex, pink color in strips on 14 pieces in cardboard packaging No. 28, 30.

Pharmacological action


Pharmacodynamics and pharmacokinetics


Drug with hypotensive action, belongs to HP, the receptors which are a specific blocker of angiotensin (AT1 type). Does not suppress the enzyme (a kinase of II) destroying bradykinin. Prezartan reduces concentration in blood of Aldosteronum and Norepinephrinum, OPSS, the ABP, reduces an afterload, pressure in a "small" circle of blood circulation, possesses diuretic action. Slows down development of a hypertrophy of a myocardium. At patients with HSN increases resistance to an exercise stress.

After a single dose of Prezartan hypotensive action reaches the maximum value in 6 hours, and for the next days — gradually decreases. The maximum hypotensive action is shown on average in a month after an initiation of treatment by drug.


Lozartan is quickly absorbed from a gastrointestinal tract. High extent of communication with blood proteins (92-99%). Bioavailability — about 33%. Elimination half-life 2 hours. Does not kumulirut in an organism, it is brought out of an organism with urine and bile.

Indications to use


High sensitivity to drug, children's age, a hyperpotassemia, the period of pregnancy and a lactation, dehydration, arterial hypotension.

Side effects

Drug is well transferred by most of patients. In rare instances: dyspepsia, diarrhea, headache, dizziness, sleep disorder, local allergic reactions, cough, hyperpotassemia, puffiness, mialgiya.

Prezartan, application instruction (Way and dosage)

Prezartan is accepted is not dependent on meal, 1 times a day. At treatment of arterial hypertension the recommended daily dose of 50 mg which, if necessary can increase to 100 mg. If the patient accepts high doses of diuretics, the dosage has to be lowered to 25 mg a day.

For treatment of HSN the initial daily dose makes 12,5 mg, taken for once, then, with a week interval the dose increases twice (12,5; 25; 50 mg). The maintenance dose makes 50 mg a day. For strengthening of hypotensive effect Prezartan is recommended to appoint N (Lozartan with an antihypertensive).


In rare instances — tachycardia, arterial hypotension.


The concomitant use of drug with the HP containing potassium (potassium drugs, kaliysberegayushchy diuretics) increases risk of development of a hyperpotassemia. The combination of administration of drug to diuretics can be the cause of sharp falling of the ABP. Joint reception of Prezartan with NPVS promotes decrease in hypotensive effect of drug. At a concomitant use of drug with other anti-hypertensive HP mutual hypotensive action amplifies.

Terms of sale

Prescription issue.

Storage conditions

At a temperature up to 25 °C.

Period of validity

36 months.

Prezartan's analogs

Brozaar, Bloktran, Vazotenz, Zisakar, Kozaar, Lozap, Kardomin-Sanovel, Lozartan, Renikard, Lakea, Vero-Lozartan, Lorista.

About Prezartana

Reviews of patients of drug positive. Prezartan is one of drugs of the combined treatment of a hypertension and an ischemic heart disease. "… I am 70 years old. From them nearly 25 years I suffer from an idiopathic hypertensia. Tried various schemes of treatment. Recently added to treatment Prezartan. The nurse explained how to accept Prezartan, and I drink him nearly three weeks. Result good". Doctors also note that addition of drug in the scheme of treatment of an idiopathic hypertensia and ischemic heart disease allows to reach long-term and stable anti-hypertensive effect, in the absence of hypotonia episodes, to achieve the target objectives of the ABP.


  • Prezartan of 50 mg No. 30 of a tabletkiipk Laboratoriz Limited
  • Prezartan of 100 mg No. 28 of a tabletkiipk Laboratoriz Limited
  • Prezartan of N 12,5mg +50mg No. 28 of a tabletkiipk Laboratoriz Limited
  • Prezartan of N 12,5mg + 50 mg No. 28 of a tabletkiipk Laboratoriz Limited

Drugstore of IFC

  • Prezartan tbl p / about 50 mg No. 30, Ipcaindiya
  • Prezartan tbl p / about 100 mg No. 28, Ipcaindiya
  • Prezartan of N tbl p/pl/o 12,5mg +50mg No. 28, Ipcaindiya
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Section: Cardiovascular
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Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

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