Прокто-Гливенол Drug photo

The description is actual on 22.08.2014

  • Latin name: Procto-Glyvenol
  • ATH code: C05AX03
  • Active ingredient: Tribenozidum + Lidocaine (Tribenoside + Lidocaine)
  • Producer: Novartis Consumer Health (Switzerland), Novartis Pharma S.a.S. (France)


As a part of one candle 400 mg of Tribenozidum and 40 mg of lidocaine contain.

As a part of 100 grams of cream 5 grams of Tribenozidum and 2 g of lidocaine + excipients contain.

Release form

Drug is let out in the form of suppositories rectal. White oblong candles let out in blisters 5 pieces, in packaging on 2 blisters.

And also in the form of the white, homogeneous, opaque cream having a specific smell. In a tuba, with a capacity of 30 grams.

Pharmacological action

Antihemorrhoidal, anesthetic (local).

Pharmacodynamics and pharmacokinetics

Tribenozidum and lidocaine in a complex remove an inflammation and anesthetize an affected area.

Active component Tribenozidum reduces permeability of vessels, reduces venous stagnation. Substance has ability to oppress activity of serotonin, a histamine and bradikinin, at the same time without influencing hormones Norepinephrinum and Epinephrinum. Drug eliminates developments of stagnation in veins, reduces patholologically a hyperpermeability of vessels. Tribenozidum removes inflammations, thanks to property to oppress him mediators, anesthetizes, removes puffiness. Ability of thrombocytes to adhesion also decreases.

Lidocaine possesses the strong anesthetizing action. It blocks natrium channels, stabilizes membranes of cells. In this regard generation and carrying out nervous impulses is slowed down.

Within two hours after introduction of a candle drug reaches the maximum concentration in blood. Biological availability reaches about 30-40%.

After putting cream from 20% (Tribenozidum) to 50% (lidocaine) of active ingredients gets to a blood stream. When putting ointment on mucous, its efficiency raises, active ingredients are soaked up more effectively.

Drug undergoes reactions of transformation into other substances in a liver which then are removed through kidneys. The part of lidocaine is removed in an original form.

Indications to use

Candles and Prokto-Glivenol ointment are appointed for topical treatment of hemorrhoids, internal and external. As a rule, within complex treatment.


Drug is not appointed to children. Inclusion in time of the first trimester of pregnancy is not recommended or at an allergy on any of means components.

Side effects

Emergence of unpleasant feelings right after introduction or drawing means on mucous is seldom possible. Urticaria, contact dermatitis, strengthenings of a vermicular movement of intestines are also possible.

Exceptional cases of emergence of a Quincke's disease, face edemas, bronchospasm, side effects from cardiovascular system are registered.

The instruction on Prokto-Glivenol (A way and a dosage)

Rektalno. Candles of Prokto-Glivenol, application instruction

Before use suppository is exempted from packaging and slightly moistened with water. Accurately enter a candle, lying on the right side, having pressed the left leg to a breast. Use on 1 candle, 2 times a day. At further treatment the dosage can be lowered to one candle.

Duration of a course is defined by the attending physician.

The instruction on ointment

In day carry out two applications of ointment, one – in the morning, the second – in the evening. The daily dosage can be lowered to one for the night.

If there is a need (hemorrhoidal nodes are located inside), it is necessary to use a special nozzle for putting cream. On average on one application ointment about a gram leaves.


Cases of overdose are not registered. Nevertheless, if candles or cream got inside, it is necessary to make a gastric lavage, to accept enterosorbents.


It is unknown whether there is an interaction of drug to other means.

Terms of sale

Existence of the recipe is not obligatory.

Storage conditions

In the cool place unavailable to children.

Period of validity

5 years.


Analogs of drug are: Anuzol, Relif Pro, Bezornil, Betiol, Pileks, Proktozan Neo, Proktosedil, Relif, Proktan, Gemorron, Beladonna's extract, Aurobin, Proktozan.

At pregnancy and a lactation

Prokto-Glivenol at pregnancy it is necessary to apply with care. During feeding by a breast administration of drug after consultation with the doctor is possible.

At pregnancy in the first trimester it is necessary to show extra care.


  • Prokto-Glivenol 2% cream 30 of tubanovartis Farm
  • Prokto-Glivenol 400 mg No. 10 svechinovartis Farm

Drugstore of IFC

  • Prokto-glivenol rekt.supp No. 10, Novartis Consumer Health/Novartisshveytsariya
  • Prokto-glivenol cream 30 of, Novartis Consumer Health/Novartisshveytsariya
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Section: Others
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