Pulmolor

Пульмолор Drug photo

The description is actual on 01.08.2016

  • Latin name: Pulmolor
  • ATH code: R05C
  • Active ingredient: Ambroxol hydrochloride + Loratadin (Ambroxol hydrochloride + Loratadine)
  • Producer: Sava Helskea of Ltd. for the applicant of "Movi Hels Gmbh", India/Switzerland

Structure

Tablets: Ambroxol a hydrochloride, loratadin, monohydrate of lactose, corn starch, povidone, microcrystallic cellulose, propylparaben, methylparaben, magnesium stearate, dioxide of colloid anhydrous, krakhmalglikolit sodium.

Suspension: Ambroxol hydrochloride, loratadin, sodium benzoate, sodium metabisulphite, edetat dinatrium, xanthane gum, silicon dioxide colloid, sukraloza, fragrance menthol.

Release form

Tablets of a rounded ploskotsilindrichesky shape of white color in the blister in cardboard packaging No. 10, 20.

Powder for suspension — in bottles of 60 and 100 ml in a cardboard pack.

Pharmacological action

Expectorant, immunomodulatory, antiinflammatory, antioxidant, antibechic.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Properties of drug are defined by pharmacological effect of actively active ingredients.

Ambroxol the hydrochloride — has the expressed mucolytic and expectorant effect, to a lesser extent — antiinflammatory, antioxidant immunomodulatory and antibechic action. The mechanism of action is caused by stimulation of functions of serous cells of glands located in mucous bronchial tubes that is promoted increase in development of a mucous secret and normalization by a ratio of mucous and serous components. As a result — rheological properties of a phlegm are normalized, its viscosity and adhesive indicators, and also, hyperreactivity of muscles of bronchial tubes decreases.

Also, stimulates activity of a ciliary epithelium of bronchial tubes that improves evacuation of a phlegm prevents adhesion of small bronchial tubes, at the same time, does not cause a bronkhoobstruktion. In lungs drug increases the content of surfactant, improves function of external respiration, stimulates local immunity.

Loratadin — treats group of the selection blockers of peripheral histamine receptors of long action. Renders antiallergic effect, eliminates a spasm of unstriated muscles, reduces permeability of capillaries, sneezing, hypostasis of fabrics, dacryagogue, rhinitis, an itch mucous the sky and a nose. Stops development and facilitates manifestations of allergic reactions. Has no sedative effect.

Pharmacokinetics

At oral administration of Ambroxol the hydrochloride is well absorbed in a gastrointestinal tract. Gets through a placental barrier, GEB, to pulmonary fabric and gets to breast milk. Bioavailability makes 100%. High communication with proteins of a blood plasma.

Cmax after administration of drug is reached in 3 hours and remains within 10–12 hours. It Biotransformirutsya in a liver, it is removed with urine in the form of metabolites. Loratadin at intake shows antihistaminic action in 2–4 hours. Cmax is reached on average in 10 hours and remains within a day.

Indications to use

Symptomatic treatment of diseases respiratory in an acute and chronic form with the spastic or not expressed allergic component, the bronchial tubes proceeding with disturbance of secretion mucous and decrease in advance of slime.

Contraindications

High sensitivity to drug, a diabetes mellitus, liver diseases, age till 12 flyings, pregnancy and the period of a lactation.

Side effects

Dyspepsia, nausea, dryness in a mouth, heartburn, vomiting, diarrhea, discomfort in a stomach, dizziness, local allergic reactions, a heart consciousness, increased fatigue, moderate tachycardia, sleeplessness, appetite increase.

Pulmolor, application instruction (Way and dosage)

Pulmolor to take a pill after food, washing down with water on 1 tablet 2 times a day or at the same time 2 tablets for two weeks once a day. Powder for suspension: with powder to add the cooled boiled water to a tag to a bottle and to shake up. To accept 5 ml after food twice a day or 1 time a day in a dose of 10 ml for two weeks.

Overdose

Overdose of drug is shown by drowsiness, a headache, a hyperemia of the person, tachycardia, abdominal pain, decrease in the ABP, nausea, diarrhea, vomiting.

Interaction

Joint administration of drug with antibiotics at bacterial infections of lungs has advantages as Ambroxol increases concentration of antibiotics in tissues of lungs and facilitates treatment of respiratory diseases. At joint Pulmolor's reception with Cimetidinum, erythromycin and ketokonazoly in a blood plasma increases concentration of a loratadin.

Pulmolor does not strengthen effect of alcohol. Joint administration of drug with CYP 2D6 and CYP 3A4 inhibitors increases concentration of a loratadin.

Terms of sale

According to the recipe.

Storage conditions

At a temperature up to 25 °C. To store ready suspension at a temperature of 2-8 °C of 14 days.

Period of validity

3 years.

Pulmolor's analogs

With similar therapeutic action treat drugs: Gedeliks, Prospan, Mucaltinum, Salbroksol, Flyuditek, Alteyka, Bronkhipret, Gederin, Ambrobene, Bronkhosan, Bronkhofit, Bronkhoval, Ambrolitin, Altemiks, Termopsol, Brovensin and others.

About Pulmolore

Majority of reviews of drug favorable.

"… After walk on skis I somewhere it is strong to catch a cold. For the 2nd day cough, at the beginning of dry began, and then there was a phlegm and temperature increased. House means were not effective and it was necessary to go to policlinic on consultation to the doctor. The diagnosis — bronchitis, several drugs including "Pulmolor" wrote out. Spent on drink 10 days, the state was normalized".

Paniapteka

  • Pulmolor por.d/oral.susp.60mlmovi Helsindiya
  • Pulmolor por.d/oral.susp.60mlmovi Helsindiya
  • Pulmolor por.d/oral.susp.60mlmovi Helsindiya
Section: For cough Immunity increase
in more detail

Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Pulmolor surely consult with the attending physician.