Рапидол Drug photo

The description is actual on 23.09.2015

  • Latin name: Rapidol
  • ATH code: N02BE01
  • Active ingredient: Paracetamol
  • Producer: Actavis Group (France)


In 1 tablet of paracetamol 125, 250 or 500 of mg.

Krospovidon, magnesium stearate, polyacrylate dispersion, a mannitol, aspartame, silicon dioxide fragrance banana — as excipients.

Release form

Tablets the dispersed (dissolved) in oral cavity 125, 250 and 500 mg. Tablets of the prolonged form of 500 mg.

Pharmacological action

Analgetic, antipyretic.

Pharmacodynamics and pharmacokinetics


Paracetamol — non-narcotic analgesic and antipyretic. Renders not expressed antiinflammatory action due to suppression of synthesis of prostaglandins.

Febrifugal action is connected with influence on the thermoregulatory center. It oppresses synthesis of the enzymes concerning pain and temperature of the central genesis. Has no peripheral effect.


It is completely soaked up at intake. The maximum concentration in blood are defined in 30–60 min. The maximum concentration in blood of the prolonged form of drug are defined in 3 hours, and action remains 10-12 hours.
It is well distributed on all fabrics, contacts blood proteins in insignificant quantity.

It is metabolized in a liver by conjugation with a chamois (at reception of high doses) and glucuronic acid. The toxic intermediate metabolite which is quickly neutralized and removed by kidneys can be formed. At children metabolic processes have features: almost all paracetamol is metabolized and toxic metabolites therefore in case of overdose of drug damages of a liver are very seldom noted are not formed.

It is removed with urine — 90% of a dose within 24 hours. An elimination half-life 2 hours, and the prolonged form — 10 hours.

Indications to use

  • headache, migraine;
  • algodismenoreya;
  • mialgiya;
  • dentagra, as well at a teething;
  • neuralgia;
  • pain at an injury;
  • fever after vaccination, at infectious diseases (a SARS, ORZ), at otitises, antritises.


Side effects

  • skin itch, the small tortoiseshell, rash on skin and mucous, a Quincke's edema;
  • nausea, pains in a stomach, increase of level of liver enzymes;
  • hypoglycemia;
  • hemolitic anemia, anemia, at long reception — aplastic anemia, thrombocytopenia, a leukopenia, an agranulocytosis;
  • at use in big dosages nephrotoxic effect of drug intersticial nephrite, renal colic is shown.

Rapidol, application instruction (Way and dosage)

Pill is taken inside, previously having dissolved in a small amount of water (for children 6 years) or rassosav in a mouth are younger (adults and children are more senior than 6 years). A pill should be taken in 1-2 hours after food, between receptions the break has to be observed not less than 4 hours.

The dosage is calculated on weight kg. To children weighing up to 40 kg 80 mg/kg of weight a day, weighing 50 kg and more, and also adult — 4 g a day are appointed. In this regard, to children of 3-6 months Rapidol 125 — on 1 tablet in 6 hours is more rational to accept, no more than 3 tablets a day. Children in 18-24 months can give up to 6 tablets in days of the same dosage each 4 hours. At more advanced age from 2 to 15 flyings appoint Rapidol of 250 from 4 to 12 tablets a day according to weight: weighing 13-20 kg — 1 g of drug a day, 21–25 kg — 1,5 g, 26–40 kg — 2 g, 41-50kg — 3 g. Adults accept Rapidol 500 every 4 hours, but no more than 4 g a day.

At the expressed pain and fever it is possible to take 2 pill on 500 mg at once.
The dispersed tablets can be applied at children from 3 months, and the retardny (prolonged) form at children from the 7th summer age and the adult. Rapidol Retard apply with an interval at 12 o'clock. Children weighing up to 40 kg accept 1-2 tablets each 12 hours, and children since 12 and adults — on 1-4 tablets.


Overdose is shown by symptoms: lack of appetite, vomiting, nausea, pallor of integuments. In 3-5 days toxic damage of a liver with the phenomena of a liver failure is shown. Treatment: hospitalization in a hospital, definition in paracetamol level blood, introduction of antidote M-atsetitsisteina, a symptomatic treatment.


The hepatotoxic of drug amplifies at co-administration of anticonvulsant drugs, Rifampicin, barbiturates. Strengthens a hepatotoxic also alcohol intake. Strengthens effect of indirect coagulants. Barbiturates reduce febrifugal effect of Rapidol. Metoclopramidum increases paracetamol absorption, and Holestiramin reduces.

Terms of sale

Without recipe.

Storage conditions

At a temperature up to 25 Pages.

Period of validity

2 years.


Paracetamol, Efferalgan.

About Rapidole

The usual tableted form of drugs causes difficulties at a proglatyvaniye, especially in children. However not all medicines can be shattered, or to crush in powder as efficiency of drug at the same time decreases. But it does not belong to the dispersed form of tablets — they need to be rassasyvat in a mouth (under the influence of saliva they are quickly dissolved) or it is possible to dissolve in an insignificant amount of water, juice or milk. In this case it is about Rapidola. Many parents positively speak of drug Rapidol for children which is easily dissolved in any liquid and does not cause problems at reception. Such form of paracetamol is also convenient for adults: it is not necessary to wash down with water as the tablet is quickly dissolved in a mouth, at once gets to a blood stream, without having negative effect on mucous a stomach, works quickly — the analgesic effect is reached in 10 — 20 minutes. The tablet does not contain dyes and is nice to the taste.

Paracetamol the antipyretic which is most often applied in pediatrics in a type of its efficiency and a high profile of safety. In responses opinions that Rapidol has more favorable form of release in comparison with syrups and suspensions which when opening a bottle it is possible to store no more than 7 days in the refrigerator meet, and then unused syrup needs to be poured out. Tablets Rapidol are stored 2 years and they can be used as necessary. Short time of effect of drug (4 hours) in comparison with the Nurofen does not arrange some.

Paracetamol does not belong to group of non-steroidal anti-inflammatory drugs therefore erosive damages of a gastrointestinal tract and a bronchospasm at its reception meet extremely seldom. Most often at administration of drug the skin itch and rashes are noted. It should be noted that despite relative safety any antipyretics need to be applied at children if fever exceeds an admissible limit (above 38-39,5 °C) and leads to disturbance of the TsNS functions and cardiovascular systems.


  • Rapidol of a tablet of 125 mg N12antibiotik (Bulgaria)
  • Rapidol of a tablet of 250 mg N12antibiotik (Bulgaria)
  • Rapidol of a tablet of 500 mg N12antibiotik (Bulgaria)
  • Rapidol
  • Rapidol


  • Rapidol of the tab. of 125 mg of N12balkanfarma
  • Rapidol of the tab. of 125 mg of N12balkanfarma
  • Rapidol of the tab. of 125 mg of N12etifarm Industries SA France
  • Rapidol of the tab. of 125 mg of N12etifarm Industries SA France
  • Rapidol of the tab. of 125 mg of N12etifarm Industries SA France
Section: Anesthetics
in more detail

Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Rapidol surely consult with the attending physician.