Рибомунил Drug photo

The description is actual on 28.05.2014

  • Latin name: Ribomunyl
  • ATH code: LO3AX
  • Active ingredient: The Ribosomalno-proteoglikanovy complex with antigens of typical bacteria
  • Producer: Pierre Fabre Medicament Production (France)


The composition of drug can slightly differ depending on a form of release of Ribomunil:

  • In addition to the main biologically active agent, include silicon (0.5 or 1.5 mg) in tablets, magnesium stearate (2 or 6 mg), sorbitol (to 294 mg or 98.4 mg). The quantity of additional components depends on the mass of initially titrated ribosomes – in the first case of an active component – 0.75 mg, and in the second – 0.25 mg. Also add proteoglycans of a cell wall in number of 1.125 mg or 0.375 mg to drug.
  • The basis of granules is made by mix of active components same, as well as in tablets with quantity of bacterial ribosomes — 0.75 mg. That is in structure is available: carbohydrate and proteinaceous components of membranes (1.125 mg), magnesium stearate (2 mg), silicon (0.5 mg) and sorbitol (98.4 mg). However for strengthening of effect and improvement of a pharmacodynamics were added: The D-mannitol to 500 mg and polividon to 10 mg.

Release form

Drug is issued in two typiforms:

  • Roundish, biconvex tablets of milk color without taste and a smell. In the blister 4 or 12 of pieces, depending on amount of biologically active component.
  • Inodorous whitish granules for preparation of drinking solution in the form of friable powder. On 500 grams in a bag, which 4 pieces in a box, that is all – 2000 grams of drug.

Pharmacological action

Complex from ribosomes and membrane proteoglycans are components of activators of upper respiratory tracts which contain the antigenic structures identical to bacterial in plentiful quantity. These components stimulate development of specific antibodies, that is possess immunomodulatory property activating systems of protection to organisms against often found strains of staphylococcus, a streptococcus, a klebsiyela and others.

Membrane carbohydrate and proteinaceous elements are capable to influence also a nonspecific immune response that is shown as:

  • Intensive macrophagic and leukocytic phagocytosis.
  • Strengthening of activity of factors of resistance of an organism (synthesis of serumal and secretory immunoglobulins, interleykina-1 and gamma interferon).

Due to development of biologically active mediators of a nonspecific immune response Ribomunil can be used not only for treatment, but also for prevention of damage of upper airways.

Pharmacodynamics and pharmacokinetics

To experimentally track transits of components of drug it is not provided possible, however there are theoretical representations according to which the ribosomalno-proteoglikanovy complex lyses with immune cells of an organism at the time of their activation. Otherwise, after absorption, biologically active agents get to a system blood stream where interact with nonspecific protection factors.

Indications to use

Ribomunil is recommended to use for prevention of slow, recurrent infectious defeats with possible heavy complications. Especially often it is applied in children's practice, since 6 months drug is included surely into a course of conservative treatment such the ENT specialist pathologies as rhinitis, otitises, quinsy, sinusitis, laryngitis, pharyngitis.

It is also recommended to use Ribomunil for prevention of an infectious invasion of respiratory tracts at people in the relevant risk groups:

  • often ill;
  • with chronic pathology;
  • in the presence of bronchial asthma;
  • if work is accompanied by professional vrednost (miners, builders and so on).


First of all from a therapeutic course this drug should appear at the available intolerance or hypersensitivity to compound chemical components of medicine.

Ribomunil at autoimmune pathologies as it will cause an aggravation of symptoms is not recommended to use.

It is possible to apply drug at a nodular periarteritis and HIV infection only at constant medical control (during hospitalization in special departments).

Side effects

As a rule, Ribomunil is had well at all age. However at the beginning of a course of treatment passing undesirable manifestations, such as can be observed:

  • Hypersalivation – the strengthened salivation.
  • The Dispepsichesky phenomena – nausea, vomiting, diarrhea, an abdominal pain.
  • System allergic reaction to drug components – a Quincke's disease, the small tortoiseshell, a generalized skin itch.
  • Sharp temperature increase to 39 degrees Celsius.

The instruction on Ribomunil (A way and a dosage)

Drug orally, on an empty stomach, preferably is used in the morning. The single dose depends on a pharmacological form:

  • 1 tablet with a dose of active component of 0.75 mg.
  • 3 tablets, if main substance of 0.25 mg.
  • The contents of one bag dissolved in boiled water if initial a type of drug – granules.

Scheme of a therapeutic course: initially drug is used the first four days a week within three weeks. Further, for maintenance of constant concentration of components – within the next five months – the first four days of every month. Thus permanent strengthening of immune system of an organism is reached.

The application instruction of Ribomunil for children is younger than 2 years has the features. So the therapeutic course of prevention can be divided into two periods for three months if there are difficulties with administration of drug in the child's organism. It is also necessary to watch some time because medicine can cause trouble breathing at organic immaturity of respiratory tracts the baby.


At the moment there are no reliable clinical data that this pharmacological drug can cause overdose.


In pharmaceutical practice cases of adverse interaction of drugs with Ribomunil are not described. So it is appointed safely with antibiotics, bronchial spasmolytics and anti-inflammatory drugs.

Terms of sale

Ribomunil is released in pharmaceutical booths without special prescription form as has no heavy side effects and contraindications with a possible lethal outcome.

Storage conditions

Drug it is necessary to store in the dry place unavailable to children of younger age, at a temperature of 15-25 degrees Celsius.

Period of validity

At observance of storage conditions, drug keeps the activity for 3 flyings.

Ribomunil's analogs

The group of immunomodulators of a bacterial origin is not numerous, however on pharmaceutical shelves it is possible to find medicinal means similar Ribomunilu are Bronkho-munal. Positive line of analog is the smaller quantity of possible side effects and shorter course of conservative prevention, but the price is slightly higher than it.

At pregnancy

Special clinical trials of action of Ribomunil on an organism of mother and child to the periods of pregnancy and a lactation it was not carried out therefore it is possible to use medicine only under supervision of the qualified medical personnel.


  • Ribomunil 0,75mg No. 4 tabletkipyer Fabr Medikament Production
  • Ribomunil of a granule of 500 mg No. 4 paketikipyer Fabr Medikament Production
  • Ribomunil of 750 mg No. 4 granulate
  • Ribomunil 0,75mg No. 12 tabletkipyer Fabr Medikament Production
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  • Ribomunilpierre Fabre Medicament Production (France)
  • Ribomunilpierre Fabre Medicament Production (France)
Section: Immunity increase
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Education: Kharkiv national medical university

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Ribomunil surely consult with the attending physician.