Roksitromitsin

Рокситромицин Drug photo

The description is actual on 09.09.2015

  • Latin name: Roxithromycin
  • ATH code: J01FA06
  • Producer: ATOLL (Russia), MEKOPHAR CHEMICAL-PHARMACEUTICAL (Vietnam), SANDOZ (Slovenia), HEXAL (Germany)

Structure

1 tablet contains 50, 150 or 300 mg of active ingredient roksitromitsin.

Release form

Is issued in the tableted form.

Pharmacological action

Antibiotic. The semi-synthetic macrolead, has bacteriostatic effect.

Pharmacodynamics and pharmacokinetics

The mechanism of action is based on linkng with ribosome subunit, suppression of reaction of transpeptidation and translocation.

Drug exerts impact on process of forming of peptide bonds between a peptide chain and amino acids, inhibits protein synthesizing by ribosomes that leads to suppression of growth and reproduction of bacterial cells.

Roksitromitsin is marked out by stability at action in acid mediums.

Indications to use

Roksitromitsin appoint at infectious damages of airways (upper, lower): a bronchoectatic disease, infections at HOBL, pneumonia, a pan-bronchiolitis, pharyngitis, bronchitis.

Drug is effective at a bacterial infection of ENT organs (average otitis, tonsillitis, quinsy, sinusitis), soft tissues and integuments (a pyoderma, a folliculitis, phlegmon, an ugly face, furuncles, the impetigo), an urinary system (a vaginitis, STD except gonorrhea, an endometritis, an urethritis, a cervicitis), bone system (osteomyelitis, a periostitis).

Medicine is applied at periodontitis, a brucellosis, erythematic rashes, trachoma, whooping cough, diphtheria, scarlet fever.

Roksitromitsin appoint for prevention at contact persons on a spotted fever, at patients with an endocarditis is after carrying out stomatologic procedures.

Contraindications

Roksitromitsin do not appoint at treatment dihydroergotamine, ergotamine, at intolerance of components, when breastfeeding, in pediatric practice till 12 flyings, at pregnancy.

At diseases of kidneys appoint with care.

Side effects

Roksitromitsin can make a food faddism, sick, pains in epigastriums, diarrhea, increase of liver enzymes, a meteorism, a hepatocellular acute hepatitis, cholestatic hepatitis, a pseudomembranous coloenteritis, pancreatitis, paresthesias, allergic reactions (a hyperemia of integuments, a bronchospasm, an acute anaphylaxis), pigmentation of nails, vagina candidiasis, mouth candidiasis, superinfection.

Roksitromitsin, application instruction (Way and dosage)

Pill is taken inside twice a day on 150 mg, or once by 300 mg.

Duration of antibacterial therapy is 5-12 days at infections of ENT organs and respiratory system.

At the chronic course of osteomyelitis treatment can last till 2,5 months.

At pneumonia of mycoplasmal and Chlamidia genesis Roksitromitsin accept 2 weeks, at legionellezny pneumonia – 3 weeks.

At pathology of kidneys accept once 150 mg.

Overdose

At overdose the urgent gastric lavage, treatment posimptomny is shown, the antidote is not developed.

Interaction

Roksitromitsin increases digoxin absorption.

At reception with fenprokoumony and warfarin raises a prothrombin time.

Strengthens and increases duration of action of a midozalam.

Increases concentration of cyclosporine A and theophylline in blood.

Roksitromitsin increases concentration of Pimozidum, tsizaprid and astemizol in blood serum.

Ergotaminpodobny vazoknstriktor and ergotamine cause forming of "ergotism", a nekrotizirovaniye of fabrics.

In blood forces out Disopyramidum in fight for blood proteins.

Terms of sale

The recipe is necessary.

Storage conditions

In the place, dark, unavailable to children, at a temperature no more than 25 degrees Celsius.

Period of validity

No more than three years.

Special instructions

Pathology of hepatic system demands regular control of indicators of work of a liver.

Roksitromitsin's analogs

Analogs of drug it is possible to call drugs: Rulid, Esparoksi, Elroks.

Zdravzona

  • Roksitromitsin Sandoz of 150 mg No. 10 tabletkisandoz Gmbh (AUSTRIA)
  • Roksitromitsin of 150 mg No. 10 tablet/ozone/ozone of Ltd company
  • Roksitromitsin Sandoz of 300 mg No. 10 tabletkisandoz Gmbh (AUSTRIA)
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BIOSPHERE

  • Roksitromitsin of 150 mg No. 10 tabl.p.o.
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Section: Antibiotics
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Education: Graduated from the Bashkir state medical university majoring in "Medical business". In 2011 gained the diploma and the certificate in Therapy. In 2012 received 2 certificate and the diploma in "Functional diagnosis" and "Cardiology". In 2013 completed courses on "Topical issues of otorhinolaryngology in therapy". In 2014 completed advanced training courses in "A clinical echocardiography" and courses in "Medical rehabilitation".

Experience: From 2011 to 2014 the Policlinic No. 33 Ufa worked as the therapist and the cardiologist in MBUZ. Since 2014 the Policlinic No. 33 Ufa works as the cardiologist and the doctor of functional diagnosis in MBUZ.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Roksitromitsin surely consult with the attending physician.