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In 100 g of cream of metronidazole of 0,75 g. Dinatrium edetat, propylene glycol, carbomer, propilparagidroksibenzoat, methylparahydroxybenzoate, sodium hydroxide, water, as
Cream and gel for external use 5, 15, 30, 50 g.
Pharmacodynamics and pharmacokinetics
Active ingredient of drug has antiparasitic and antimicrobic effect and shows activity concerning many microorganisms.
Drug is active concerning the following microorganisms: Helicobacter pylori, Bacteroides fragilis, Bilophila, Clostridium, Bifidobacterium, Clostridium, Eubacterium, Fusobacterium, Prevotella, Peptostreptococus, Prophyromonas, Veillonella, and also protozoa: Entamoeba histolytica, Trichomonas vaginalis. Actinomycetes are steady against drug. It is effective at treatment of a rozatse, especially in a phase of pustular elements.
At outside use concentration is much higher, than in blood. The maximum concentration of metronidazole in serum makes 32,9 ng/ml that no more than 1% of its maximum concentration at oral administration. The concentration peak at use of ointment is noted in 6-20 hours.
Indications to use
Hypersensitivity to ingredients.
- local reactions in the form of burning, an itch, reddenings, prickings (at excessive drawing);
- urticaria, contact dermatitis are possible.
Rozeks, application instruction (Way and dosage)
Cream is applied outwardly twice a day. To apply with a thin layer on the cleared affected areas. To avoid hit in eyes, on mucous lips and a nose. Treatment duration on average 3-4 months.
In case of development of undesirable reactions use of cream is cancelled. At accidental hit on mucous membranes it is necessary to wash out them water. During treatment to avoid stay on the sun.
Cases are not registered.
At external use cases of any interaction with medicines are not registered.
Terms of sale
Temperature is up to 25 °C.
Period of validity
Skin diseases bring discomfort, and it is twice unpleasant if manifestations affect them the person. And the rozatsea causes many psychological problems, especially if the disease progresses: symmetric erubescence of cheeks becomes more noticeable, extends to a forehead and a chin, the inflamed acne rash joins.
Completely and a vospaleeritemaniye do not disappear and it is impossible to get rid of this disease, but to stop development quite perhaps. The cream of Rozeks combining antiinflammatory, antiprotozoan and antimicrobic action is choice drug at this disease.
Cream has the balanced basis that improves penetration of active agent in skin and metronidazole renders necessary effect at lower concentration, in comparison with analogs. It is established that this cream has twice the best bioavailability. Lower concentration provides good tolerance of drug and does not cause side effects, considering that cream can is long to be applied. About drug is different probably it is connected with the fact that duration of a disease and degree of manifestation of symptoms at all different therefore also efficiency of treatment also different.
- "… The dermatologist recommended ointment of Rozeks, applied 3 months — the effect is. The doctor told that not aggravations it was necessary to carry out the supporting treatment".
- "… Helped to remove an inflammation, but in a month the illness did not recede at all".
- "… After several weeks of use the skin whiteness returned, from an inflammation there is no trace left. drug not from cheap, but rescues".
- "… Helps well, but I use cheaper analogs".
- "… Cream worsened a condition of skin, did not help me absolutely".
- "… It is forced to interrupt treatment, there was an itch and a bigger irritation, probably, something did not approach".
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