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Medazepamum, monohydrate of lactose, potato starch, gelatin, magnesium stearate; sikovit orange, talc.
Tablets of 10 mg of a round form, flat orange color in dark glass bottles in cardboard packaging No. 50.
Pharmacodynamics and pharmacokinetics
Derivative benzodiazepine, possesses anksiolitichesky, antiepileptic, myorelaxation and in insignificant degree — timoleptichesky action. To a lesser extent has sedative and somnolent effect. On force of action concedes to benzodiazepine tranquilizers, treats group of "day" tranquilizers. Eliminates sensation of fear, psychoneurotic tension, a condition of alarm, excess fussiness, motive excitement, normalizes an emotional background, stabilizes a vegetative nervous system. Recovers a possibility of critical evaluation of a disease.
It is quickly soaked up from a gastrointestinal tract. Absorption at the level of 49-75%. The maximum concentration in blood is reached on average in 2 hours. High communication by blood proteins — 99.8%. It Biotransformirutsya in a liver by oxidation, a hydroxylation with formation pharmacological of active metabolites: diazepam, nordiazepam, desmetildiazepama, oxazepam.
Metabolites are removed with urine and a stake. For 10-14 days after the end of administration of drug in plasma considerable concentration of the nordiazepam having sedative effect are defined.
Indications to use
Various neurotic disturbances which are followed by an alarming state, concern, fear, psychovegetative and psychosomatic frustration (a menopausal syndrome, sleep disorders, irritability, migraine, mental lability and others).
High sensitivity to drug, alcoholism and drug addiction, dysfunctions of a liver and kidneys, the expressed myasthenia, age till 10 flyings, the I trimester of pregnancy, functional disorders of breath during a night dream.
Feeling of fatigue, drowsiness, headache, dizziness, weakness, oglushennost, depression, ecmnesia, confusion of consciousness, accommodation paresis, decrease in a libido, potentiality, frustration of a menstrual cycle, oppression of a respiratory center, decrease in the ABP, tachycardia, dyspepsia, dryness in a mouth, a withdrawal, local allergic reactions, an ischuria, paradoxical reactions, a spasm of phonatory bands, medicinal dependence.
At patients of advanced age and at children orientation loss, increased fatigue, aggression, lack of braking are possible.
Rudotelum, application instruction (Way and dosage)
To take a pill on an empty stomach, washing down with water. A daily dose for adults: 10–30 mg for 2–3 receptions a day or in the evening for an hour to withdrawal to a dream once on an empty stomach. If necessary, the dosage can increase to 40 mg, and in stationary conditions — to 60 mg. To patients after 60 flyings the daily dose decreases to 10–20 mg/days. To children after 10 flyings the daily dose should not exceed 1,0 mg/kg.
Duration of administration of drug is defined by a psychoemotional condition of the patient: at acute conditions of excitement, an emotional stress or fear administration of drug is limited several days or even to single doses. At chronicities duration of reception varies from 1 to 3 weeks, but should not exceed one month. After prolonged use drug withdrawal has to be carried out gradually, reducing a dose for a week.
The main symptoms of overdose of drug are drowsiness, muscular weakness, an ataxy, confusion of consciousness, sharp lowering of the ABP, in rare instances — cyanosis, a loss of consciousness, in extremely hard cases — a cardiac standstill.
Mutually strengthens action of neuroleptics, antidepressants, antihistaminic drugs, hypnagogues, ethanol, anesthetics, opioid analgetics. Cimetidinum, Disulfiramum and omeprazol extend and strengthen action of Rudotelum. Drug oppresses action of a levodopa. Theophylline reduces the calming effect of Rudotelum.
Terms of sale
At a temperature up to 25 °C.
Period of validity
Analogs of Rudotelum
Coincidence on the ATH code of the 4th level:
Medazepamum, Mezapamum, Nobrium, Nobritem.
About drug favorable.
- "… It is long I have a depression and I leave it by means of this drug".
- "… Because of loss of work and the long period of disorder and a lack of money a constant depression, sleeplessness, alarm, uncertainty in the future, frequent differences of mood. The neuropathologist appointed Rudotelum. The alarm decreased, began to sleep more or less normally, but I am afraid of accustoming to it".
Section: For a nervous system
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