Sorbifer Durules

Сорбифер Дурулес Drug photo

The description is actual on 22.05.2014

  • Latin name: Sorbifer Durules
  • ATH code: B03AA07
  • Active ingredient: Ascorbic acid + Ferrous sulfate
  • Producer: JSC Farmatsevtichesky plant Egis, Vergriya

Structure

Sorbifer Durules contains in one tablet active ingredients: ferrous sulfate – 0,32 g, ascorbic acid – 0,06 g + excipients (povidone, carbomer 934P, a macrolog 6000, strearat magnesium, polyethene powder, titanium dioxide, paraffin, a gipromelloza, yellow iron oxide).

Release form

Drug is let out in the form of tablets of yellow color, convex, with a letter Z on the one hand. If to pull down a tablet in half, the kernel of gray color will be visible. In packagings on 30 or 50 pieces.

Pharmacological action

Iron preparation possesses antianemic impact on an organism.

Medicine MNN: gland sulfate + ascorbic acid.

Pharmacodynamics and pharmacokinetics

Medicinal properties of drug are caused by existence in its composition of iron in combination with ascorbic acid.

Iron, in itself, is an integral part of a human body, its important functional unit. It is a part of hemoglobin, takes part in oxidizing reactions in fabrics. Ascorbic acid improves quality and influences assimilation speed an iron organism.

The special form, matrix in which medicine is issued provides gradual and slow release of iron. Process proceeds not in a stomach, and in a duodenum and a jejunum, under the influence of a vermicular movement. Process is characterized by high extent of absorption and bioavailability. More than 90% of active iron contact blood proteins. The elimination half-life makes about six hours.

Indications to use

Medicine is appointed:

  • at deficit of iron in an organism;
  • anemias (because of a lack of iron);
  • as a prophylactic at pregnant women and the feeding women and blood donors.

Contraindications

  • medicinal allergy;
  • hemosiderosis and hemochromatosis;
  • other types of anemias;
  • thrombosis and thrombophlebitis;
  • diabetes mellitus and intolerance of fructose;
  • stenoses of bodies of a gastrointestinal tract;
  • urolithiasis and other serious diseases of kidneys;
  • children (till 12 flyings);
  • parallel administration of drugs, containing iron, problems with digestion of iron in an organism.

At inflammations and a peptic ulcer of bodies of a gastrointestinal tract means is applied only to destination and under supervision of the doctor.

Side effects

The most widespread side effects are:

  • lock, diarrhea, nausea and pains in epigastric area;
  • reddening and itch on skin, the Quincke's edema is possible;
  • hyperglycemia;
  • administration of drug promotes formation of stones and sand in kidneys;
  • thrombocytosis, erythrocytopenia, leukocytosis;
  • deviations from the normal content and an exchange of zinc and copper in an organism are possible;
  • headache, weakness, tachycardia, dizziness;
  • blackening or darkening calla.

Application instruction Sorbifer Durules (Way and dosage)

According to the instruction on Sorbifer, swallow of a tablet entirely, without chewing and without dividing into parts, wash down with water.

As a rule, if the doctor did not appoint differently, the daily dose makes 2 tablets (no more than four) distributed on two receptions. The course of treatment can make 3-4 months.

How to accept drug at pregnancy?

In the preventive purposes, appoint on one tablet a day, during treatment – 2 tablets. Therapy proceeds before recovery of level of iron in an organism.

Overdose

Increased fatigue, weakness, lowering of arterial pressure, abdominal pains and vomiting with blood are overdose signs.

It is necessary to ask as soon as possible for the help the doctor, to make a gastric lavage, to give to drink the person milk and crude egg, to enter Deferoxaminum.

Interaction

You should not combine administration of drug with ciprofloxacin, norfloxacin, levofloksatsiny, ofloksatsiny and Moksifloksatsiny.

The combination of food additives to the content of calcium and magnesium, captopril, clodronate, Cimetidinum, levodopa, zinc, a desferoksamin, Methyldopum, tetracycline, a penitsilinamin, hormones of a thyroid gland, Pancreatinum, ethanol and tocopherol with Sorbifer is not recommended. The interval between drug intake has to leave for less than two hours.

The drug combination to ascorbic acid can lead to overdose by iron.

Process of absorption of medicine worsens at a combination to milk, the eggs, tea, coffee, juice, bread, products rich with vegetable fibers. Also assimilation is negatively influenced by oral contraceptives and chloramphenicol.

Terms of sale

The recipe is required.

Storage conditions

In the place unavailable to children, temperature is not higher than 25 degrees.

Period of validity

3 years.

Analogs Sorbifer Durules

Coincidence on the ATH code of the 4th level:

Feroplekt, gemoferon, loretin forte, globigen, aktiferin, gemsinerad-td, totem, ranferol-12.

The price of analogs is a little lower, than at the original.

That it is better: Maltofer or Sorbifer?

Drugs are almost identical, there is an opinion that the maltofer is better acquired and has less side effects. In total individually.

That it is better: Sorbifer or Fenyuls?

Fenyuls contains twice less iron, than Sorbifer. Helps at insignificant degree of anemia. The original copes with disease symptoms quicker.

With alcohol

At a medicine combination to ethanol, extent of absorption of iron amplifies. Strengthening of side reactions is possible.

Drugstore of IFC

  • Sorbifer durules tbl p / about No. 30, Egisvengriya
  • Sorbifer durules tbl p / about No. 50, Egisvengriya
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Apteka24

  • Sorbifer durules tablets coated No. 30egis (Hungary/France)
  • Sorbifer durulesegis (Hungary)

Paniapteka

  • Sorbifer durules the tab. p / about No. 30egis
  • Sorbifer durules the tab. p / about No. 30egis

BIOSPHERE

  • Sorbifer Durules No. 50 tabl.p.o. Egis Pharmaceutical plant of joint stock company (Hungary)
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Section: Vitamins Immunity increase
PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Sorbifer Durules surely consult with the attending physician.