Stopdiar

Стопдиар Drug photo

The description is actual on 26.08.2014

  • Latin name: Stopdiar
  • ATH code: A07AX03
  • Active ingredient: Nifuroksazid (Nifuroxazide)
  • Producer: Gedeon Richter (Hungary)

Medicine Stopdiar — structure

Tablets in a film cover. Are a part of one tablet:

  • active ingredient nifuroksazid 100 mg;
  • excipients: talc, silicon dioxide colloid, potato starch, gelatin, magnesium stearate;
  • structure of a film cover: talc, gipromelloz, titanium dioxide, polyethyleneglycol 20000, quinolinic yellow dye.

Suspension for intake, in 5 ml of suspension contains:

  • active ingredient nifuroksazid 220 mg;
  • excipients: carbomer, sucrose, sodium hydroxide, monohydrate of citric acid, 30% antifoam emulsion of a simetikon, methylparahydroxybenzoate, banana fragrance.

Release form

Tablets in a film cover of yellow color, round, convex on both sides. 24 tablets are in the blister placed in cardboard packaging.

Suspension for intake of light-lemon color, with a banana smell in bottles of dark glass of 125 ml (suspension in a bottle of 90 ml). The bottle is placed in cardboard packaging, in the same place is double (since both ends) measured to a spoon on 5 and 2,5 ml.

Pharmacological action

Drug possesses antibacterial action in relation to causative agents of intestinal infection.

Pharmacodynamics and pharmacokinetics

Active ingredient of Stopdiar nifuroksazid belongs to group of nitrofurans and at intake has antibacterial effect on pathogenic and the opportunistic microorganisms causing intestinal infections. Nifuroksazid is active in relation to gram-positive (staphylococcus, to streptococci) and gram-negative (to salmonellas, shigellas, klebsiyella, colibacillus) to bacteria which most often are causative agents of intestinal infections.

Stopdiar's action is connected with suppression of effect of the enzymes participating in a cellular metabolism of contagiums. Because of disbolism membranes of cells of bacteria collapse and cells perish.

Stopdiar's activity in relation to contagiums does not decrease even at a long course of treatment. At the same time it does not destroy useful intestinal microflora therefore after its use on recovery of process of digestion less time is required, than at use of antibiotics. Effect of drug does not depend on acidity in intestines.

After intake of capsules or suspension active ingredient is practically not soaked up in intestines, does not get to blood and has no systemic action on an organism. It works directly in intestines, and then is brought out of an organism in the natural way with a fecal masses.

Indications to Stopdiar's use

Drug is appointed at the following diseases:

  • the acute intestinal infections caused by activators, sensitive to a nifuroksazid;
  • chronic diseases of intestines (enterita and coloenterites) of infectious character.

Contraindications for Stopdiar's use

Contraindications for use of tablets:

  • allergy to medicines from group of derivatives 5 nitrofurans;
  • hypersensitivity of an organism to other components of drug;
  • age till six years.

Contraindications for suspension use:

  • allergy to medicines from group of derivatives 5 nitrofurans;
  • hypersensitivity of an organism to other components of drug;
  • age about two months;
  • prematurity.

With care it is recommended to take medicine during pregnancy and feeding by the child's breast as clinical tests on these categories of patients it was not carried out.

Side effects of Stopdiar

Drug is usually well transferred by all patients and only in isolated cases its side effects are shown:

  • from a stomach and intestines – there can be passing abdominal pain, nausea, displays of a diarrhea will amplify; it does not demand interruption of a course of treatment;
  • allergic reactionssmall tortoiseshells, a Quincke's edema, breath disturbance. Under such circumstances it is necessary to stop administration of drug immediately.

Application instruction of Stopdiar

The instruction on tablets Stopdiar: swallow of tablets without chewing and washing down with water each 6 hours. Stopdiar's reception does not depend on a diet. Adults and children after six years should accept 200 mg (2 tablets) 4 times a day within a week.

The instruction on Stopdiar — suspension for children: each 6 – 8 hours give suspension to the child, without connecting it with feeding; the bottle before use is carefully stirred up, trying to obtain uniformity of suspension then dose suspension by means of a measured spoon (1 small measured spoon on 2.5 ml contains 110 mg of medicine, 1 big measured spoon on 5 ml — 220 mg). The instruction for children recommends the following age dosages of drug:

  • 2 – 6 months: 110 – 220 mg (1-2 measured spoons on 2.5 ml) twice a day;
  • 6 months — 6 years: 220 mg (1 measured spoon on 5 ml) three times a day;
  • 6 — 18 years and adult: 220 mg (1 measured spoon on 5 ml) four times a day.

Suspension use duration Stopdiar for children should not exceed one week. Treatment has to be carried out under control of the doctor as intestinal infection, especially, at small children, often leads to dehydration and related heavy to complications. Therefore it is required to make up for loss of liquid constantly.

Stopdiar's interaction with other medicines

Drug is practically not soaked up in intestines and does not come to blood therefore cannot interact with any other medicinal substances. But if at the same time with Stopdiar to take inside some other medicine, Stopdiar adsorbs it on the surface and will bring out of an organism. Therefore between intake of Stopdiar and other medicines there has to be a break 2 – 3 hours.

Interaction with alcohol

During treatment by Stopdiar it is impossible to take alcoholic drinks as reception of this drug sharply increases sensitivity of an organism to alcohol. Even at accidental reception of a small amount of alcohol development of heavy teturamopodobny reaction is possible: at the patient arterial pressure sharply decreases, there are nausea, vomiting, sometimes a loss of consciousness and spasms.

Terms of sale

Drug is released according to the recipe of the doctor.

Storage conditions

Tablets store in the dry dark place, at a temperature of 15-25 °C. Suspension should be stored at a temperature not above 25 °C. Medicines have to be unavailable to children.

Period of validity

Period of validity of tablets – 4 years, suspensions — 3 years.

Stopdiar's analogs

Coincidence on the ATH code of the 4th level:

Analogs are drugs of different medicinal groups which are used for treatment of identical diseases. Stopdiar's analog is Furasolidone – drug of their group of nitrofurans, but with other active ingredient. Furasolidone is one of the first drugs from group of derivative nitrofurans which began to be appointed at treatment of intestinal infections. Efficiency, certainly, is lower than it, than at Stopdiar.

Synonyms of drug are Enterofuril, Ersefuril, Diastat, Nifuroksazid. In all these medicines active ingredient is nifuroksazid.

Enterofuril or Stopdiar — what is better?

These are absolutely identical drugs which have the same active ingredient, are issued in identical dosage forms for adults and children, have identical indications and contraindications for use.

Both drugs let out the pharmaceutical companies with good reputation: Stopdiar – Gideon Richter (Hungary), Enterofuril — Bosnalek (Bosnia and Herzegovina).

Zdravzona

  • Stopdiar of 100 mg No. 24 tabletkigedeon Richter
  • Stopdiar suspension 220mg/5ml 90 of ml No. 1 flakongedeon Richter

Drugstore of IFC

  • Stopdiar tbl p/pl/o 100 mg No. 24, Gedeon Richtervengriya
  • Stopdiar suspension for intake 220mg/5ml 90 ml, Gedeon Richtervengriya
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BIOSPHERE

  • Stopdiar of 220 mg / 5 ml of 90 ml susp. for reception vnutrgedeon Richter Poland Ltd company (Poland)
  • Stopdiar of 100 mg No. 24 tabl.p.p.o. Gideon Richter Poland Ltd company (Poland)
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Section: Gastrointestinal Antimicrobic
PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Stopdiar surely consult with the attending physician.