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As a part of 1 gram of means gel Troxevasinum Neo contains 20 mg of a trokserutin, 1,7 mg of heparin sodium, 50 mg of a dekspantenol.
Additional substances: trolamin, propylene glycol, carbomer, propilparagidroksibenzoat, methylparahydroxybenzoate, water.
Yellowish transparent gel.
- 40 grams of gel in an aluminum tuba — 1 tuba in a pack from a cardboard.
- 40 or 100 grams of gel in a plastic tuba — 1 tuba in a pack from a cardboard.
Local antitrombotichesky, venotoniziruyushchy, angioprotektorny and regenerative action.
Pharmacodynamics and pharmacokinetics
Multicomponent drug for topical administration.
Trokserutin is angioprotektorny means. Shows R-vitamin activity: has venoprotektorny, venotoniziruyushchy, antiinflammatory, antiedematous, antioxidant and anticoagulative action. Reduces permeability and fragility of small vessels, strengthens their tone. Increases density of a wall of vessels. Contributes to normalization of perfusion and a trophicity of fabrics, stops congestive processes.
Heparin belongs to anticoagulants of direct type, a natural anticoagulative factor. Brakes a thrombogenesis, stimulates fibrinolitic indicators of blood, improves a local blood stream. Has antiinflammatory action, improves recovery of connecting fabric in view of hyaluronidase inhibition.
Dekspantenol in cells of skin is transformed to the pantothenic acid which is a component of a coenzyme And which regulates in processes of oxidation and acetylation. Improving a metabolism, dekspantenol promotes recovery of fabrics which are damaged; stimulates heparin absorption.
At local use all above-mentioned active ingredients are actively absorbed by skin.
Trokserutin already half an hour later is found in a derma, and 3-5 hours later — in a hypodermic fatty tissue. Trokserutin almost does not get into a system blood stream.
Heparin usually collects in blankets and actively reacts with proteins of skin. At topical administration only the insignificant volume of heparin gets into a blood stream, without causing systemic action, without rendering changes of indicators of a blood coagulation. Through a placental barrier does not get.
Dekspantenol actively gets into cells of skin and is transformed to pantothenic acid, reacts with proteins of plasma (beta globulin and albumine). In turn pantothenic acid in an organism is not metabolized and removed in an original form.
Indications to use
- Venous insufficiency of chronic type with the accompanying onychalgias, puffiness, feeling of weight and fatigue of legs, spasms, vascular asterisks, paresthesias.
- Varicose dermatitis.
- Hypostases and pains of posttraumatic character (at stretchings, bruises, injuries).
- The open infected wounds or wounds with strong exudation in the field of drawing.
- Hypersensitivity to drug components.
- Age till 18 flyings.
Reactions of allergic type: rash, itch.
Application instruction Troxevasinum Neo (Way and dosage)
Troxevasinum Neo is applied exclusively outwardly. A thin film of drug is applied on the necessary area to two times a day (in the morning and in the evening), distributing it evenly on skin the rubbing movements before final absorption. In case of need it is authorized to apply gel under elastic stockings and bandage.
The effect of treatment by drug mainly depends on its regular use for an appreciable length of time. The course of therapy makes usually 2-3 weeks. Needs in more long treatment are defined by the doctor.
About 3 once a year are recommended to conduct additional courses of therapy.
It is improbable because from insignificant system absorption of active components of gel.
Interaction of means Troxevasinum Neo with other medicines is not revealed.
Terms of sale
To store at the room temperature. To protect from children.
Period of validity
It is necessary to avoid hit of medicine on mucous membranes, in eyes and on open wounds.
Troxevasinum Neo cannot be used in ophthalmology, and also to enter intravaginalny or rectal.
At administration of drug negative influence on ability of driving of motor transport was not observed.
Coincidence on the ATH code of the 4th level:
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