Tsefekon D

Цефекон Д Drug photo

The description is actual on 24.07.2015

  • Latin name: Cefecon D
  • ATH code: N02BE01
  • Active ingredient: Paracetamol
  • Producer: Nizhpharm, JSC, Nizhny Novgorod, Russian Federation

Structure

Are Paracetamol in various dosage a part of candles and Vitepsol as candle weight.

Release form

Candles (suppositories) V-of a figurative form, rectal for children, in the blister packaging on 5 candles in a cardboard pack No. 10.

Pharmacological action

Analgeziruyushchy, slight antiinflammatory, febrifugal.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Children's Tsefekon has analgeziruyushchy and febrifugal effect. In TsNS drug causes cyclooxygenase blockade, influencing thereby the painful center and system of thermal control. In the inflammation center influence of paracetamol on cyclooxygenase is neutralized by peroxidase of cells that considerably reduces antiinflammatory effect. Tsefekon does not influence negatively a mucous membrane of a gastrointestinal tract and a water and electrolytic exchange, that is, the sodium water delay in an organism is not noted.

Pharmacokinetics

Drug possesses high absorption, is quickly soaked up through a mucous membrane. Easily overcomes GEB. Possesses high bioavailability. It is distributed mainly in fluid mediums of an organism. Linkng with proteins insignificant (less than 10%). It is metabolized in a liver. The maximum concentration of drug in blood comes within 10-60 minutes after its reception. It is removed by kidneys in the form of inactive metabolites (sulfates and glucuronides).

Indications to use

Drug is appointed to children in quality:

  • antipyretic. Are appointed at the flu, a SARS, postvaccinal reactions, infections of children's age and other states causing fervescence;
  • analgeziruyushchy means at a pain syndrome (neuralgia, a mialgiya, head and tooth pain, pains at burns and injuries).

Contraindications

To children till 1 month, hypersensitivity to paracetamol, an alcoholism. It is necessary to appoint drug with care at diseases of system of the blood expressed to dysfunction of kidneys and a liver, genetically caused enzymatic absence glyukozo-6-fosfatdegidrogenazy.

Tsefekon — it is possible to appoint candles D at pregnancy and a lactation taking into account advantage and risk for the pregnant woman and the child (fruit). In researches of teratogenic, mutagen and embriotoksichesky effect of paracetamol it is not established.

Side effects

Nausea, vomiting; anemia, agranulocytosis, leukopenia, thrombocytopenia; allergic reactions (an itch and rash on mucous membranes and skin, the small tortoiseshell), development of a papillary necrosis and intersticial nephrite, hemolitic anemia.

The instruction on Tsefekon D

Suppository is entered to the child or the teenager rektalno. On candles Tsefekon D for children is recommended to enter candles after a cleansing enema into instructions. Suppository is entered by 2 — 3 times a day. The single dose of Tsefekon D on average should not exceed 15 mg on kilogram of weight of the child, and the most daily dose — 60 mg.

Drug of special function is demanded by children's age of 1 - 3 month — one-time administration of one suppository (0.05 g of paracetamol) in days.

Aged from 3 months till one year weighing child of 6 - 10 kg the dose of drug makes 1–2 candles on 0,1 g; 1–3 years with the body weight of 10-15 kg 1–2 candles on 0,1 g; 3–10 years (weight of 16-32 kg) 1 candle on 0,25 g; 10–12 years (weight of 33-36 kg) 2 candles on 0,25 g.

Tsefekon — candles for children the instruction does not recommend to use is long. Tsefekon's reception D for decrease in temperature is limited for 3 days, and for removal of pain — to use no more than five days.

Overdose

There is no information on overdose of drug.

Interaction

At a concomitant use with salicylates the risk of development of nephrotoxic action sharply increases. At co-administration with Paracetamol toxic effect of chloramphenicol amplifies, efficiency of means, slowing down synthesis and accelerating a conclusion of uric acid decreases, the effect of anticoagulants of indirect action amplifies.

Terms of sale

Without recipe.

Storage conditions

At a temperature not above 20 °C.

Period of validity

3 years.

Analogs

There is a lot of analogs of the drug "children's Tsefekon" containing paracetamol in the structure.

Let's mark out only some of them: Paracetamol children's, Children's Panadolum, Taylenol children's, Bindard (sparkling powder for children), Daynafed of EH, Volpan (powder), Daynafed the junior, Dafalgan, Deminofen, Kalpol the 6th plus, MS Paracetamol, Efferalgan and others.

About Tsefekona D

On numerous the Internet the forums discussing drugs for children About candles Tsefekon confirm high performance of drug. Tsefekon D is especially irreplaceable when the child refuses flatly to accept febrifugal and anesthetics in the form of drink (syrups) or tablets or at the child vomiting after syrup reception begins.

Some parents in the presence at the child of temperature give him an antibiotic that categorically cannot be done without consultation with the doctor. Do not forget that temperature is defense reaction of an organism and in moderate limits it does not need to be reduced. Do wet rubdowns to the child, give plentiful drink.

Febrifugal candles Tsefekon for children are an optimal variant, however it is worth to remember that it is impossible to accept children's candles from temperature more than 3-5 days. Besides drug not the road. Information from forums confirms that candles for children whose structure contains paracetamol are rather popular among parents. Often at forums ask "through how many candles Tsefekon D work?". As a rule, the effect appears in 15-20 minutes and lasts till five o'clock.

Some parents face the choice "that it is better: Tsefekon or Nurofen?" and whether it is possible Tsefekon and the Nurofen at the same time to give to the child? These two drugs have various active agents (paracetamol and an ibuprofen). Here all individually. Tsefekon, in others — the Nurofen is in certain cases more effective. It is not recommended to give at the same time Tsefekons the Nurofen. If between reception, for example, of the Nurofen temperature rises, reduce rubdown. However, if your child accepts five days Tsefekon, and temperature does not fall, then it is necessary to replace Tsefekon with other drug. But it is impossible to give to the child one drug, between receptions of another.

Sometimes parents use for decrease in temperature at the child of a candle for adults. It cannot be done as most of parents cannot correctly calculate a dose for the child. It is better to use the drug intended for children.

Zdravzona

  • Tsefekon D for children of 100 mg No. 10 svechinizhfarm joint stock company
  • Tsefekon D for children of 50 mg No. 10 svechinizhfarm joint stock company
  • Tsefekon D for children of 250 mg No. 10 svechinizhfarm joint stock company

Drugstore of IFC

  • Tsefekon D candles for is put. 100 mg No. 10, Nizhpharm (N. Novgorod) Russia
  • Tsefekon D candles for is put. 250 mg No. 10, Nizhpharm (N. Novgorod) Russia
  • Tsefekon D candles for is put. 50 mg No. 10, Nizhpharm (N. Novgorod) Russia
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Apteka24

  • Suppositories tsefekon D 0.05g No. 10 Nizhpharm (Russia)
  • Suppositories tsefekon D 0.1g No. 10 Nizhpharm (Russia)
  • Suppositories tsefekon D 0.25g No. 10 Nizhpharm (Russia)

Paniapteka

  • Soup. tsefekon D 0.05g No. 10 Nizhpharm
  • Soup. tsefekon D 0.05g No. 10 Nizhpharm
  • Soup. tsefekon D 0.05g No. 10 Nizhpharm
  • Soup. tsefekon D 0.05g No. 10 Nizhpharm

BIOSPHERE

  • Tsefekon of D 100 mg No. 10 supp.rekt.detsk. Nizhpharm (Russia)
  • Tsefekon of D 250 mg No. 10 supp.rekt.detsk. Nizhpharm (Russia)
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Section: Anesthetics Anti-cold
in more detail

Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Tsefekon D surely consult with the attending physician.