Цифран Drug photo

The description is actual on 24.06.2014

  • Latin name: Cifran
  • ATH code: J01MA02
  • Active ingredient: Ciprofloxacin (Ciprofloxacin)
  • Producer: Indian company "RANBAXY LABORATORIES"


One tablet contains 250, 500 or 1000 mg of active component of ciprofloxacin. Additional substances: talc, a gidroksipropilmetiltsellyuloz, sodium alginate, magnesium stearate, krospovidon, colloid silica gel on an anhydrous basis, hydrosodium carbonate.

Tsifran SR. in addition contains 600 mg of Tinidazolum.

100 ml of solution contain 200 mg of a lactate of ciprofloxacin.

Release form

The medicine is issued in the tableted look and in the form of solution.

Pharmacological action

Tsifran, is an antibiotic or not?

Yes, the principle of antimicrobic influence is based on an obstacle of reproduction of a bacterium that conducts to death of a microorganism. Drug influences gram-positive bacteria and the gram-negative flora steady against effect of aminoglycosides, penicillin and cephalosporins. The antimicrobic effect is observed in all bodies and systems, suppressing infectious process and an inflammation that allows to apply an antibiotic at a dentagra.

The operating component in Tsiprolet's drug is ciprofloxacin therefore actually Tsiprolet and Tsifran one and too on pharmacological action.

Tsifran OD – the prolonged ciprofloxacin of long action.

Pharmacodynamics and pharmacokinetics

Concerning gram-negative flora the bactericidal (destroying) effect in a phase of division and rest is shown (active agent influences a fermental DNK-girazu and causes death, a lysis). Tsifran 500 affects gram-positive flora only during division. In macroorganisms is absent fermental DNK-giraza that does ciprofloxacin low-toxic for the person. Parallel development of resistance to other antimicrobic medicines (tetracyclines, aminoglycosides) against treatment is not observed. Stability forms very slowly.

Indications to Tsifran's use

From what tablet Tsifran? The medicine is appointed at the bacterial infections caused by microorganisms which are sensitive to influence of an antibiotic of ciprofloxacin.

Diseases of respiratory system:

Diseases of ENT organs:

Diseases of an urinogenital path:

Infections of an abdominal cavity:

  • cholera;
  • typhoid;
  • shigellosis;
  • peritonitis;
  • salmonellosis.

From what Tsifran can be still appointed: the burns, phlegmon, septic arthritis, osteomyelitis infected ulcers, sepsis.

Tsifran SR. appoint at hard proceeding mikst-infections: empyema, sinusitis, decubituses, dysentery.


At mental diseases, the expressed atherosclerotic changes in a brain, an epileptic syndrome, pathology of renal system drug is appointed with care, weighing possible complications and the expected result. It is not recommended to use to elderly people.

Side effects (undesirable reactions)

Cardiovascular system:

Digestive tract:

  • cholestatic jaundice (is more often at predisposed persons);
  • appetite disturbance;
  • diarrheal syndrome;
  • nausea;
  • epigastric pains;
  • gepatitgepatonekroz.

Nervous system:

  • uneasiness;
  • headaches;
  • fast fatigue;
  • sleep disorders;
  • peripheral paralgeziya (disturbance of perception of a pain syndrome);
  • hyperhidrosis;
  • various psychotic reactions.

Sense bodys:

  • disturbance of acoustical perception;
  • sonitus;
  • disturbance of color perception, diplopia;
  • food faddism.

Urinogenital path:

The allergic answer in the form of the small tortoiseshell, medicinal fever, an epidermal necrolysis is possible. Seldom the mialgiya, an arthralgia, ruptures of sinews, change from blood is registered.

Application instruction of Tsifran (Way and dosage)

How to accept drug: for increase in biological availability it is strongly recommended to take a pill next the heart. During the entire period of treatment the increased water use is required. Infusional administration of solution is possible only intravenously within 0,5-1 hours.

Treatment of uncomplicated pathology of an urinogenital path: each 12 h on 250 mg.

Treatment of prostatitis, heavy pathology urinary system: twice a day on 500 mg.

Treatment of LOR-pathology, diseases of respiratory system, typhoid: on 500 mg each 12 hours. In hard cases medicine is recommended to be entered parenterally according to the scheme: 200 mg (a bottle of 100 ml) slowly intravenously twice a day (increase in a single dose up to 400 mg is possible).

The instruction on Tsifran SR.: a pill needs to be taken after food, without destroying integrity of a protective cover. The recommended dosage of-250\300 mg (a ratio of active agents of ciprofloxacin and Tinidazolum) twice a day on 2 tablets.

Application instruction of Tsifran AUDE: reception of a medicine on an empty stomach accelerates antibacterial effect. The recommended scheme of treatment: on 250 mg 2-3 times a day.


High doses of a medicine increase expressiveness of side reactions. The induction of vomiting, adequate hydration, carrying out posimptomny therapy is recommended. The special antidote is not developed.


Level of theophylline increases at simultaneous treatment by ciprofloxacin. It is recommended to maintain a 4-hour window between Tsifran's receptions and the drugs containing zinc, iron, magnesium, sukralfat, aluminum. Anti-inflammatory, nonsteroid drugs strengthen the stimulating impact of a medicine on a nervous system. Obligatory control of a koagulogramma at warfarin reception is required.

Terms of sale

Issue according to the prescription form.

Storage conditions

In the dry place, temperature mode – to 25 degrees.

Period of validity

2 years. At loss of a deposit the medicine admits unsuitable solution.

Special instructions

The prevention of a crystalluria requires the sufficient use of liquid during treatment. It is recommended to avoid solar radiation.

Analogs Tsifrana SR.

The combined drug Tsifran SR. has no substitutes. Analogs of medicine Tsifran: Tsiprinol, Tsiprobay, Tsiprolet.


  • Tsifran of 500 mg No. 10 tabletkiranbaxy
  • Tsifran of 250 mg No. 10 tabletkiranbaxy
  • Tsifran SR. of 500 mg + 600 mg No. 10 tabletkiranbaxy
  • Tsifran solution for infusions 2mg/ml 100 ml No. 1 flakonranbaxy
  • Tsifran AUDE of 500 mg No. 10 tabletkiranbaxy

Drugstore of IFC

  • Tsifran tbl p / about 500 mg No. 10, Ranbaxyindiya
  • Tsifran SR. tbl p / about 500+600mg No. 10, Ranbaxyindiya
  • Tsifran tbl p / about 250 mg No. 10, Ranbaxyindiya
  • Tsifran AUDE tbl p / about prolong.1000mg No. 10 *, Ranbaxyindiya
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  • Tsifran AUDE of a tablet 500 of mg No. 5ranbaksi (India)
  • Tsifran odranbaxy (India)
  • Tsifran SR. of a tablet 500 of mg No. 10ranbaksi (India)


  • Tsifran AUDE of the tab. of 1000 mg No. 5ranbaksi
  • Tsifran AUDE of the tab. of 1000 mg No. 5ranbaksi
  • Tsifran AUDE of the tab. of 1000 mg No. 5ranbaksi


  • Tsifran OD of 1000 mg No. 5 tabl.p.o.ranbaxy (India)
  • Tsifran of 250 mg No. 10 tabl.p.o.ranbaxy (India)
  • Tsifran SR. of 500 mg No. 10 tabl.p.o.ranbaxy (India)
  • Tsifran of 200 mg 100 ml solution for инф.Ranbaxy (India)
  • Tsifran of 500 mg No. 10 tabl.p.o.ranbaxy (India)
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Section: Antibiotics
in more detail

Education: Graduated from the Bashkir state medical university majoring in "Medical business". In 2011 gained the diploma and the certificate in Therapy. In 2012 received 2 certificate and the diploma in "Functional diagnosis" and "Cardiology". In 2013 completed courses on "Topical issues of otorhinolaryngology in therapy". In 2014 completed advanced training courses in "A clinical echocardiography" and courses in "Medical rehabilitation".

Experience: From 2011 to 2014 the Policlinic No. 33 Ufa worked as the therapist and the cardiologist in MBUZ. Since 2014 the Policlinic No. 33 Ufa works as the cardiologist and the doctor of functional diagnosis in MBUZ.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Tsifran surely consult with the attending physician.