Cinnarizine

Циннаризин Drug photo

The description is actual on 05.02.2015

  • Latin name: Cinnarizine
  • ATH code: N07CA02
  • Active ingredient: Cinnarizine
  • Producer: Atoll of Ltd company (Russia), Biosynthesis of joint stock company (Russia), Actavis Group hf. (Iceland), Sopharma AD (Bulgaria), Dalkhimfarm (Russia), Asfarm (Russia)

Structure

Active agent cinnarizine weighing 25 mg is a part of tablets.

Additional substances are: magnesium stearate, povidone, monohydrate of lactose, silicon dioxide, potato starch.

Release form

Drug is issued in the form of tablets of white color.

Also Cinnarizine Forte from 75 mg of active ingredient is issued.

Pharmacological action

According to the summary expands vessels. Improves peripheric and cerebral circulation.

Pharmacodynamics and pharmacokinetics

Reduces intake of calcium in a cell, reduces calcium level in depot of a plasmolemma, strengthens vasodilating effect of carbon dioxide, reduces a tone of smooth muscle fabric of arterioles. Cinnarizine has vasodilating effect, does not influence a blood pressure. Antihistaminic activity of medicine is expressed moderately, reduces a tone of a sympathetic nervous system, moderately reduces excitability of a vestibular mechanism. Cinnarizine is effective at patients with latent option of insufficiency of cerebral circulation, at an initial form of atherosclerosis of brain vessels, after a stroke. At persons with the broken peripheric circulation improves food of fabrics, bodies, a myocardium, increases post-ischemic expansion of a gleam of vessels. Cinnarizine reduces an indicator of viscosity of blood, moderately increases ability of erythrocytes to deformation, positively influences elasticity of their membranes.

The maximum absorption happens within 1-3 hours. It is brought in the form of metabolites with urine to one third and with a stake to two thirds. The elimination half-life makes 4-24 hours.

Indications to Cinnarizine use

From what tablet? Drug is appointed after an ischemic stroke, after the postponed brain injuries, distsirkulyatorny encephalopathy, Minyer's illness, vestibular disturbances, for prevention of kinetoz.

What indications to use of Cinnarizine exist still? Medicine is effective at a Raynaud's disease, an obliterating thromboangiitis, senile dementia, migraine, sea and air bolezny, obliterating atherosclerosis, thrombophlebitis, angiopatiya, paresthesias, trophic disturbances.

Contraindications

Drug is contraindicated at a lactation, during pregnancy incubation, to children till 12 flyings. At Parkinson's illness appoint with care.

Side effects

Nervous system: increased fatigue, drowsiness, extrapyramidal frustration, depression, hyperkinesia, tremor of extremities, headaches.

Side effects from the alimentary system: the cholestatic jaundice, dispepsichesky frustration which are taking place pains in epigastriums, dryness in a mouth.

The increased sweating, allergy, falling of arterial pressure is seldom noted, red flat deprive, obesity.

Tablets Cinnarizine, application instruction (Way and dosage)

Drug is accepted inside. Medicine in pricks does not exist.

At disturbance of blood supply of a brain: three times a day on 25-50 milligrams.

At disturbance of peripheral blood supply: three times a day on 50-75 mg.

Prevention of sea and air diseases: in 30 minutes prior to an event accept 25 milligrams.

Labyrinth frustration: three times a day on 25 milligrams.

To children since 12 the dosage is reduced twice. The age is less than 12 years contraindication to the drug use.

The effect is reached at continuous treatment.

It is impossible to use more than 225 mg of a medicine a day.

The application instruction Cinnarizine of Sofarm of 25 mg is similar.

Overdose

Drowsiness, vomiting, coma, excessive falling of a blood pressure, tremor. Reception of adsorbents, posimptomny therapy is recommended. The antidote is not developed.

Interaction

Cinnarizine strengthens action of nootrop, sedative, vasodilating, antihypertensives, ethanol. Reduces effective action of hypertensive means.

Terms of sale

The recipe is required.

Storage conditions

In the place, unavailable to children, at a temperature no more than 25 degrees Celsius.

Period of validity

No more than 5 years.

Special instructions

Cinnarizine can be the cause of false positive doping control at athletes. Such effect is explained by antihistaminic effect of medicine. Prolonged use demands control over work of a liver, kidneys, a condition of blood. It is admissible to accept drug when feeding by a breast. Influences management of transport.

Often appoint a combination of Cinnarizine and Piracetam at chronic insufficiency of cerebral circulation. Interaction of these substances is in detail described in Wikipedia.

Cinnarizine for babies

How to accept for newborns? It is important to remember that medicine is contraindicated for babies.

Analogs of a medicine are: Stugeronum, Tsinarizin.

About Cinnarizine

Those who accepted drug estimate it as effective and inexpensive. Medicine helps to cope with a headache, increases intellectual working capacity, cleans a sonitus and dizziness.

About Cinnarizine for children

Doctors sometimes appoint medicine to babies, and parents demonstrate that it helps, without putting visible negative impacts. However, it is worth remembering that this medicine is contraindicated to children till 12 flyings.

The Cinnarizine price where to buy

The price of the tablets Cinnarizine makes 30 rubles for 50 pieces.

Zdravzona

  • Cinnarizine of Sofarm of 25 mg No. 50 tabletkisopharma AD
  • Cinnarizine 25 of mg No. 50 of a tabletkimoskhimfarmpreparata to them N. A. Semashko of joint stock company
  • Cinnarizine 25 of mg No. 50 PFK Tablet/updating/updating of closed joint stock company
  • Cinnarizine 25 of mg No. 50 tablet/ozone/ozone of Ltd company

Drugstore of IFC

  • Cinnarizine tbl 25 mg No. 50, Adbolgariya's Farm
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Apteka24

  • Tsinnarizinoz GNTSLS (Ukraine, Kharkiv)
  • No. 50lekhim-Kharkiv mg tablet 25 cinnarizine (Ukraine, Kharkiv)
  • Cinnarizine fortekiyevmedpreparat (Ukraine, Kiev)

Paniapteka

  • Cinnarizine of the tab. of 25 mg No. 50OZ GNTsLS
  • Cinnarizine of the tab. of 25 mg No. 50OZ GNTsLS
  • Cinnarizine of the tab. of 25 mg No. 50OZ GNTsLS
  • Cinnarizine of the tab. of 25 mg No. 50OZ GNTsLS

BIOSPHERE

  • Cinnarizine of 25 mg No. 50 of table.
  • Cinnarizine of Sofarm of 25 mg No. 50 of table.
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Section: Cardiovascular
in more detail

Education: Graduated from the Bashkir state medical university majoring in "Medical business". In 2011 gained the diploma and the certificate in Therapy. In 2012 received 2 certificate and the diploma in "Functional diagnosis" and "Cardiology". In 2013 completed courses on "Topical issues of otorhinolaryngology in therapy". In 2014 completed advanced training courses in "A clinical echocardiography" and courses in "Medical rehabilitation".

Experience: From 2011 to 2014 the Policlinic No. 33 Ufa worked as the therapist and the cardiologist in MBUZ. Since 2014 the Policlinic No. 33 Ufa works as the cardiologist and the doctor of functional diagnosis in MBUZ.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Cinnarizine surely consult with the attending physician.