Урсолизин Drug photo

The description is actual on 20.07.2016

  • Latin name: Ursolisin
  • ATH code: A05AA02
  • Active ingredient: Ursodezoksikholevy acid (Ursodeoxycholic acid)
  • Producer: Magis Farmaceutici S.p.A. (Italy)


Ursodezoksikholevy acid, corn starch, magnesium stearate, silicon dioxide anhydrous, titanium dioxide gelatin.

Release form

Capsules Ursolizin 150 and Ursolizin of 300 mg in the blister in a cardboard pack No. 20, 100.

Pharmacological action

Litolitichesky, gipokholesterinemichesky, the cytoprotective and gepatoprotektivny, anti-cholestatic and holeretichesky, immunomodulatory.

Pharmacodynamics and pharmacokinetics


The drug dissolving cholesteric concrements in a gall bladder. Ursodezoksikholiyevy acid which is present at an organism as a part of bile in the form of ksenodezoksikholiyevy or holiyevy acid is its part. Ursolizin promotes process of transformation of bile litogenny in not litogenny that interferes with formation of cholesteric stones and promotes their dissolution. Thereby cholelithiasis symptoms including dyspepsia are eliminated.


Drug is absorbed in a gastrointestinal tract, mainly at the level of a colonic and ileal gut. After administration of drug Smakh it is reached in 30 minutes. It is metabolized in a liver. Ursodezoksikholevy acid in the form of conjugates with bile and partially – with a stake is removed.

Indications to use

  • Treatment of a chronic and acute hepatitis, biliary cirrhosis, dyskinesia of zhelchevyvodyashchy ways, cystous fibrosis of a liver, damages of a liver of a toxic and alcoholic etiology, sclerosing cholangitis, cholestasia, for dissolution of bilious cholesteric stones in the general bilious channel and a gall bladder;
  • Prevention of damages of a liver at treatment by cytostatics, antitubercular drugs, long use of hormonal contraceptives.


High sensitivity to drug, obstructive jaundice, diseases of a gall bladder and zhelchevyvodyashchy ways in an acute phase, pregnancy (women). To take with caution the patient with diseases of intestines and pancreas, to patients with frequent hepatic gripes in the anamnesis.

Side effects

Ursodezoksikholiyevy acid in rare instances can make dizziness, sick, vomiting and diarrhea, local allergic reactions, a febricula, a mialgiya, an alopecia, an exacerbation of psoriasis, increase of content of enzymes of a liver.

Ursolizin, application instruction (Way and dosage)

Capsules are recommended to be accepted entirely, washing down with water. It is recommended to accept together with food. Treatment duration by drug and doses is determined by the doctor. On average, at the gastritises which are followed by a bile reflux a dose of drug makes 150-300 mg a day for 14 days.

At chronic hepatitis with a cholestasia and at cirrhosis drug is accepted in a dose at the rate of 10 mg/kg of a body a day. In the presence of concrements with a diameter less than 10 mm administration of drug in a dosage of 300-600 mg/days for 6-12 months is recommended.


Ursolizin's use in doses, therapeutic considerably exceeding can promote development of symptoms of intoxication (a headache, nausea, vomiting, diarrhea, pain in a stomach).


Joint administration of drug with Colestyraminum and other HP breaking process of absorption of bile acids in intestines is not recommended. Not to trample down along with the drugs strengthening removal of cholesterol with bile (hypolipidemic and estrogensoderzhashchy drugs).

Terms of sale

Prescription issue.

Storage conditions

At a temperature up to 25 °C.

Period of validity

36 months.

Ursolizin's analogs

Ursosan, Ursofalk, Holudeksan, Ukrliv, Ursokhol, Ursodeks, Livodeksa, Urdoksa and others.

About Ursolizin

Most of patients with problems with a gastrointestinal tract speak of drug well.

"… Though I have gastritis long ago with these drug got acquainted with a bile reflux recently. After the next aggravation I addressed to paid hospital where the doctor appointed to me treatment and ursodezoksikholiyevy acid including. Practically in 3 days the state improved".

Judging by responses at many patients Ursolizin's use leads to reduction of the sizes of cholesteric stones in a gall bladder and to decrease in frequency and intensity of gripes.


  • Ursolizin kaps. 300 mg No. 100magik of Farmasyyutitsi (Italy)
  • Ursolizin of a capsule of 150 mg No. 20magik of Farmasyyutitsi (Italy)
  • Ursolizin of a capsule of 300 mg No. 20magik of Farmasyyutitsi (Italy)


  • Ursolizin kaps. 150 mg No. 20magik of Farmasyyutitsi
  • Ursolizin kaps. 150 mg No. 20magik of Farmasyyutitsi
  • Ursolizin kaps. 150 mg No. 20magik of Farmasyyutitsi
Section: For a liver Others
in more detail

Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Ursolizin surely consult with the attending physician.