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Valine – eurysynusic aliphatic alpha amino acid, is one of 20 proteinogenous irreplaceable amino acids. Connection was for the first time allocated from casein in 1901 by the chemist E. Fischer.
Chemical formula of Valine: HO2CCH(NH2)CH(CH3)2, racemic formula of Valine: C5H11NO2. The molecular mass of connection = 117,15 grams on mol, substance density – 1,230 grams on ms3. The constitutional formula of Valine is in detail considered in article on Wikipedia. Means has 2 space D and L isomers. Synthesize amino acid in the form of colourless crystals. L-valine is well dissolved in water, aqueous solutions of alkalis, badly dissolved in organic solutions.
It is possible to synthesize substance action of NH3 on an alpha bromizovalerianovuyu acid. Since 1982 means is made around the world, approximately on 150 tons per year. In a live organism amino acid is one of the main components participating in processes of growth and synthesis of living tissues, raises muscular coordination and reduces sensitivity of an organism to pain and other adverse factors of environment. The main sources of Valine are: meat of chicken, salmon and beef; cow's milk, eggs, walnuts; wheat and cornmeal; peas and crude rice.
Pharmacodynamics and pharmacokinetics
This amino acid plays a key role in processes of synthesis and growth of tissues of body, is an energy source of cells of muscles, prevents falling of level of serotonin and development of depressions. Substance considerably increases quality of muscular coordination and reduces sensitivity of an organism to cold, a heat, Bol and to stresses. Means possesses ability to protect a myelin cover — important part of nerve fibrils of a head and spinal cord. This substance is necessary for an organism to support a normal exchange of nitrogen.
Means reaches the maximum efficiency in combination with a leucine and an isoleucine. This amino acid is irreplaceable, that is the organism cannot independently synthesize it. Getting to a system blood stream substance completely is metabolized, does not collect in fabrics.
Indications to use
Amino acid Valine is appointed in combination with other medicines:
- for ensuring parenteral food;
- as preventive and a remedy at intensive loss by an organism of proteins;
- at injuries, burns, sepsis and peritonitis;
- after extensive operative measures;
- as a part of complex treatment of inflammatory diseases of intestines and a gastrointestinal tract;
- at a depression, drug addiction, multiple sclerosis;
- as a prophylactic at the raised exercise stresses.
Means is contraindicated:
- at disturbances of processes of a metabolism of amino acids;
- to patients with an allergy to this substance;
- at a heavy renal failure or overhydratation;
- the patient with a metabolic acidosis.
Amino acid Valine, as a rule, is well transferred, side reactions arise extremely seldom. Allergic reactions can develop.
Valine, application instruction (Way and dosage)
Depending on a dosage form and appointment use various schemes of treatment by drugs on the basis of Valine. The dosage and duration of reception are defined by the attending physician.
Overdose cases are not described by this means.
This amino acid can be combined practically with all medicines.
Terms of sale
The recipe is not required.
Infusions of the drugs containing amino acid are recommended to be made slowly to increase efficiency of therapy.
At a renal failure correction of a dosage of means can be required.
At pregnancy and a lactation
Medicine can be accepted during pregnancy and during the lactation periods according to indications.
Drugs in which contains (Analogues)
Drugs as a part of which there is an amino acid Valine: Aminoven, L-valine, Aminoplazmal B. Brown E 10, Aminoven Infant, Kabiven, Aminosol-Neo, Aminoplazmal E, Aminosteril, Infezol, Moriamin, Nefrotekt, Nutrifleks, Tserebrolizat, Haymiks.
The Valine price where to buy
Drug cost Infezol makes about 3500 rubles for 10 bottles with a capacity of 150 ml. It is possible to buy amino acid in industrial packaging approximately for 700 rubles, 200 grams.
Section: Active ingredients
PAY ATTENTION! Information on active ingredients on the website is help generalizing, collected from public sources and can form the basis for making decision on use of these substances it is not aware of treatment. Before substance Valine use surely consult with the attending physician.