Valsartan

Валсартан Drug photo

The description is actual on 07.02.2015

  • Latin name: Valsartan
  • ATH code: C09CA03
  • Active ingredient: Valsartan (Valsartan)
  • Producer: KRKA (Slovenia), Obolenskoye — the pharmaceutical enterprise, Ozone of Ltd company (Russia), Second Pharma Co., Livzon Group Changzhou Kony Pharmaceutical Co., Zhuhai Rundumintong Phamaceutical Co., Ltd. (China), Maylen Laboratoriz Limited (India)

Structure

Drug contains valsartan as the operating component.

Tablets on 40 mg include the following additional components: magnesium stearate, kroskaramelloza of sodium, microcrystallic cellulose, Opadray Pink dye.

Tablets on 80 and 160 mg contain the following auxiliary elements: kroskaramelloza of sodium, magnesium stearate, Opadray Pink dye, microcrystallic cellulose, aerosil.

Release form

Medicine is on sale in drugstores in the form of powder, capsules, granules and tablets.

Pharmacological action

Anti-hypertensive drug.

Pharmacodynamics and pharmacokinetics

Active agent of drug provokes competitive blocking of receptors of AT1 of angiotensin II which are in a vascular endothelium, a cardiac muscle, bark of adrenal glands, renal fabric, a brain and pulmonary fabric. It leads to inhibition of angiotenzinovy effects. Medicine reduces a myocardium hypertrophy at arterial hypertension.

After single use the effect is swept up in 120 minutes, it lasts for days. Permanent therapeutic action is reached 3 weeks later after the first day of a course.

At people with HSN medicine liquidates hyper stimulation of RAAS, interferes with pathological proliferation of cells, reduces puffiness. Its reception reduces preloading and increases cordial emission.

At a combination to Captopril reduces probability of postinfarction complications.

Besides, such combination as valsartan and amlodipin is widespread. These active components contain in such drugs as Eksforzh and Vamloset.

Original drug is quickly absorbed from a gastrointestinal tract. Bioavailability on average – 23%.

Communication with proteins of plasma (mainly with albumine) – about 95%.

It is excreted mainly with a stake (70%), it is also removed with urine (30%), generally in an invariable look.

Indications to use

Drug is used at arterial hypertension, and also for increase of survival of people with an acute myocardial infarction which is complicated by systolic dysfunction of a left ventricle and/or a left ventricular failure. In case of chronic heart failure it is used as making complex treatment.

Contraindications

It is impossible to use in case of hypersensitivity to components of medicine, pregnancy, breastfeeding. For children efficiency and safety of means are not established.

Side effects

Reception of this medicine can cause some undesirable effects:

  • CCC and system of a hemopoiesis: neutropenia, decrease in a hematocrit, hyperpotassemia;
  • TsNS: dizziness, weakness, headache;
  • digestive tract: diarrhea, abdominal pains, nausea, increase in activity of hepatic transaminases;
  • others: cough, viral infections, hyperpotassemia.

Side reactions at use of drug appear seldom.

Application instruction of Valsartan (Way and dosage)

For those who use Valsartan the application instruction reports that means is intended for the peroral use. The recommended dosage in case of arterial hypertension makes 80 mg. The norm in a day is accepted in one step. If necessary the dosage can be brought to 160 mg or in addition to use other anti-hypertensive drug. The application instruction of Valsartan specifies that the maximum daily dosage – 320 mg. It is not recommended to exceed it.

Overdose

Overdose symptoms – hypotension, bradycardia, tachycardia. Treatment symptomatic. The dialysis of efficiency has no.

Interaction

Drug strengthens effect of diuretics. The drugs including potassium in structure and also kaliysberegayushchy diuretics increase probability of a hyperpotassemia.

Terms of sale

According to the recipe from the specialist.

Storage conditions

Temperature is up to 25 °C. It is necessary to store drug in the place protected from light and unavailable to children.

Period of validity

Three years. It is impossible to apply on expiry date, specified on packaging.

Valsartan's analogs

The following synonyms and Valsartan's analogs are known:

  • Valz;
  • Valaar;
  • Valsartan And;
  • Valsasin;
  • Valsartan of N;
  • Valsartan Zentiva;
  • Valsakor;
  • Diovan;
  • Valsafors;
  • Nortivan;
  • Tantordio;
  • Tareg.

All listed drugs have the features of use. Valsartan's analogs cannot be replaced at discretion, without consultation with the doctor.

About Valsartana

About Valsartana mainly approving. Those who used this means, note its fast action. Responses of doctors also testify to the expressed hypotensive activity of medicine.

Zdravzona

  • Valsartan Zentiva of 160 mg No. 28 of a tabletkizentiv
  • Valsartan Zentiva of 160 mg No. 84 of a tabletkizentiv
  • Valsartan Zentiva of 80 mg No. 28 of a tabletkizentiv
  • Valsartan Zentiva of 80 mg No. 84 of a tabletkizentiv
  • Valsartan of 160 mg No. 30 tabletkiozon Ltd company

Drugstore of IFC

  • Valsartan-Zentiva tbl p/pl/o 160 mg No. 28, Zentiva A.S.Chekhiya
  • Valsartan-Zentiva tbl p/pl/o 160 mg No. 84, Zentiva A.S.Chekhiya
  • Valsartan-Zentiva tbl p/pl/o 80 mg No. 28, Zentiva A.S.Chekhiya
to show still
Section: Cardiovascular
PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Valsartan surely consult with the attending physician.