Вальцит Drug photo

The description is actual on 08.07.2016

  • Latin name: Valcyte
  • ATH code: J05AB14
  • Active ingredient: Valgantsiklovir (Valganciclovir)
  • Producer: F. Hoffmann-La Roche Ltd. (Switzerland)


Valgantsiklovira a hydrochloride, krospovidon, povidone, microcellulose, a gidroksipropilmetiltsellyuloza, stearic acid, polyethyleneglycol, titanium dioxide, polysorbate, ferrous oxide, the water purified.

Release form

Tablets of 450 mg in a film cover convex an oval form, pink color in polyethylene bottles in cardboard packaging No. 60.

Pharmacological action


Pharmacodynamics and pharmacokinetics


Drug with antiviral action (pro-medicine) – represents valilovy ether of a gantsiklovir which under the influence of intestinal and liver enzymes after reception is quickly transformed in gantsiklovir. Anti-virus activity of a gantsiklovir is based on suppression of process of synthesis of DNA of viruses by competitive embedding of a deoxyguanosine of triphosphate in structure of DNA that leads to stopping of process of lengthening or very limited lengthening of DNA of viruses.

Gantsiklovir is synthetic analog of the deoxyguanosine which is actively influencing reproduction process reproduction herpes of viruses. Actively influences a virus of a herpes simplex, hepatitis V, TsMV, Epstein-Barre's virus, chicken pox. At prolonged treatment by drug a number of viruses can have a resistance to a gantsiklovir that is caused by processes of mutations and selection.


Valgantsiklovir is well and quickly soaked up from a gastrointestinal tract. In a liver and a wall of intestines valgantsiklovir it is transformed in gantsiklovir. Linkng of a gantsiklovir with blood proteins insignificant. The metabolism happens by hydrolysis to formation of a gantsiklovir. It is removed through kidneys.

Indications to use


High sensitivity to drug, a neutropenia (it is less 500/mkl), a heavy renal failure, thrombocytopenia, age till 12 flyings, pregnancy, a lactation.

To take with caution to patients of advanced age and in the presence of the expressed renal failure.

Side effects

Fatigue, nausea, diarrhea, vomiting, fever, anemia, neutropenia, abdominal pains, abdominal distention, dyspepsia, an abnormal liver function, ascites, weakness, sinusitis, infections of urinary tract, bronchitis, flu, sleeplessness, paresthesias, a headache, a tremor, spasms, confusion of consciousness, a hallucination, psychotic frustration, hypostases, dermatitis, an itch, night perspiration, pneumonia, cough, cold, spasms in muscles, indistinct sight, arterial hypotension, an arthralgia.

Valtsit, the application instruction (A way and a dosage)

To accept drug of Valtsit inside during food.

Induction therapy

To patients with active TsMV a retinitis to accept drug in a dose of 900 mg twice a day for 3 weeks. Further transition to a maintenance therapy — a dosage of 900 mg once a day. At an aggravation of symptoms of the patient to repeat a course of induction therapy.

Valtsit's use at a renal failure — selection of a dose is carried out on the basis of an indicator of clearance of creatinine.

Prevention of TsMV of an infection at the patients who transferred an organ transplantation. The recommended dose — 900 mg of 1 times a day, since 10 days after transplantation and till the 100th day.


It is most often shown by an abnormal liver function, hepatitis, a leukopenia, a granulocytopenia, an acute renal failure, diarrhea, abdominal pains, vomiting, spasms, a tremor.


Gantsiklovir increases zidovudine AUC, and the zidovudine reduces slightly concentration of a gantsiklovir. Joint reception of a gantsiklovir with a zidovudine increases probability of development of anemia and a neutropenia. Zaltsitabin increases AUC of a gantsiklovir. The concomitant use of a gantsiklovir with the drugs possessing nephrotic or myelotoxic action can strengthen toxic effect of these drugs. Trimethoprimum lowers renal clearance of a gantsiklovir.

Terms of sale

Prescription issue.

Storage conditions

At a temperature up to 30 °C.

Period of validity

36 months.

Valtsit's analogs

Valgantsiklovir, Tsivalgan.

About Valtsita

About drug among doctors positive. "… Clinical data demonstrate that "Valtsit" in treatment of a cytomegalovirus is more effective than traditional means, despite a form of production of drug. In prevention of development of the TsMV-infection after a heart transplantation, a liver, kidneys, within the first half a year, at patients, at administration of drug, the indicator of rejection of bodies decreased and the transplant survival indicator about 100 days of rehabilitation increased".


  • Valtsit 450 mg No. 60 tabletkihoffman La Roche
to show still
Section: Antiviral
in more detail

Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before use of medicine of Valtsit surely consult with the attending physician.