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In 1 tablet of diosmin of 600 mg.
Starch corn, povidone, microcrystallic cellulose, magnesium stearate — excipients.
Pharmacodynamics and pharmacokinetics
Diosmin thanks to active flavonoids has venotoniziruyushchy effect: raises a tone of veins, reduces distensibility and eliminates venous stagnation.
The Venotoniziruyushchy effect has dozozavisimy character. Vazoket improves a lymphatic drainage, raising a tone of lymphatic capillaries and frequency of their reduction, reducing pressure in a lymphatic bed.
Improves microcirculation, influencing permeability of capillaries, improves diffusion of oxygen and as a result the trophicity of fabrics improves. Has moderate antiagregantny effect, suppressing process of "sticking" of leukocytes to a wall of veins. Possesses antiinflammatory action (blocks synthesis of prostaglandins).
It is well soaked up from a gastrointestinal tract and in 2 hours the maximum concentration — in 5 hours is found in blood, and. Collects in walls of venas cava and outside veins of extremities. Selective accumulation of drug in veins remains 96 hours. Diosmin is removed mainly with urine, a stake and bile.
Indications to use
- peripheral lympho-venous insufficiency;
- microcirculation disturbance;
- varicosity of the lower extremities;
- the increased fragility of capillaries;
- exacerbation of hemorrhoids.
There are data that Vazoket can be appointed for prevention of bleedings which arise after introduction of intrauterine spirals, and also during a phlebectomy.
- the age is less than 18 years;
- hypersensitivity to drug;
Vazoket, application instruction (Way and dosage)
Vazoket 600 at lympho-venous insufficiency (peripheral) and a varicosity — on 1 tablet in the morning before meal. Course of treatment 2 months.
At the expressed lympho-venous insufficiency — 3-4 months, at trophic ulcers prolong till 6 months. Course treatment is repeated every 6 months.
At an exacerbation of hemorrhoids of 7 days to accept 2-3 tablets of times a day during food, then on 1 tablet a day 1-2 months. The application instruction of Vazoket contains a reminder that at an exacerbation of hemorrhoids treatment is carried out in a complex with other HP.
In the II—III trimester of pregnancy at venous insufficiency — 1 tablet a day. Drug is cancelled in 3 weeks prior to childbirth.
Does not meet, symptoms are not described.
Effects of interaction with other drugs are not described. During treatment alcohol intake is not recommended.
Terms of sale
It is released according to the recipe.
In the dry place, it is not higher than 300 Pages.
Period of validity
Coincidence on the ATH code of the 4th level:
Clinical tests of Vazoket do not meet, it is possible to meet Flebodiya's research and Detralex more often. However, there are responses of the practicing phlebologists who appointed this drug at a varicosity. Analyzing comments of doctors on Vazoketa it is possible to draw a conclusion that at patients good tolerance of drug is noted, allergic reactions meet extremely seldom in spite of the fact that a course of treatment drug not less than 3 months 2 times a year.
The elastic compression (stockings, panty hoses or bandaging) was surely applied. At all patients reduction of expressiveness of symptoms of HVN, positive influence of drug on dynamics of healing of trophic ulcers was noted. Upon completion of a course of treatment the steady effect within 2 months on condition of carrying compression jersey remained.
Vazoket or Flebodia — what is better?
The concept "best" — collective from "effective", "safe", "available". Choosing means for treatment, it is necessary to compare all factors: active ingredient, possible side effects, duration of courses of treatment and cost of drugs.
The Flebodia and Vazoket have one active ingredient — a bioflavonoid diosmin which defines therapeutic action. The Flebodia (Innothera Chouzy, France) contains 600 mg of diosmin, Vazoket 600 also — 600 mg of diosmin and a little different excipients that is not so essential. The truth it is important for some patients as on components of drug there can be a reaction.
Vazoket's cost from 635 rub to 804 rub, and is slightly higher than Flebodia the 600th No. 30 — from 650 rub to 1046 rub.
It is considered to be that original drug (in this case — Flebodia) is better than generics. However, Weimer Pharma GmbH (Germany) — the producer Vazoketa takes the worthy place in the pharmaceutical market and as medicines of this company you should not doubt.
Drugs of Flebodia and Vazoket are identical by efficiency and possible side effects.
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