Ventrisol

Вентрисол Drug photo

The description is actual on 12.07.2016

  • Latin name: Ventrisol
  • ATH code: A02BX05
  • Active ingredient: Bismuth trikaliya dicitrate (Bismuthate tripotassium dicitrate)
  • Producer: Poznanskie Pharmaceutical Works Polfa (Poland)

Structure

Bismuth a trikaliya dicitrate, cellulose, magnesium stearate, silicon dioxide, polyethyleneglycol, metotset, polividon, potato starch.

Release form

Tablets in a cover of 120 mg in the blister in cardboard packaging No. 112.

Pharmacological action

Gastroprotektivnoye.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Antiulcerous drug with the knitting and antiinflammatory action, bakteritsidno active Helicobacter pylori is relative. At pH of a gastric juice lower than 4 process of sedimentation of insoluble bismuth of oxychloride and formation of a sheeting of ulcerated sites (an insoluble complex of chelate connections with protein substrate) begins.

Drug reduces activity of pepsin, stimulates synthesis of PgE promoting the strengthened production of slime and a hydrocarbonate, increases activity of cytoprotective mechanisms that promotes accumulation in a zone of defect of an epidermal growth factor and stimulates process of healing of defects (ulcers) of a mucous membrane.

Pharmacokinetics

The main active ingredient of drug (bismuth) from a gastrointestinal tract is practically not soaked up. The dose — through kidneys is removed through intestines and in small.

Indications to use

Gastritis, the caused Helicobacter pylori, an aggravation of a gastroduodenit, a peptic ulcer of a stomach.

Contraindications

Acute gastritis, high sensitivity to drug, HPN, the period of pregnancy and a lactation.

Side effects

Allergic reactions, nausea, diarrhea, vomiting. At administration of drug in high doses for an appreciable length of time — the encephalopathy caused by accumulation in bismuth TsNS.

Ventrisol, application instruction (Way and dosage)

To take inside for half an hour to food, the adult — 4 times a day 120 mg; to children till 12 flyings – twice a day on 120 mg, washing down with water (not to wash down with milk) for 1-2 months. The following course of treatment can be begun after a 2-month break.

For treatment of the gastritis caused by Helicobacter pylori administration of drug combine with Metronidazole reception inside and Amoxicillin — 250 mg 4 times a day (each of them) within 10 days.

Overdose

Long administration of drug in the doses exceeding therapeutic causes poisoning with bismuth which is shown by symptomatology of a renal failure and existence of high concentration of bismuth in blood.

Interaction

It is necessary to refrain from meal, liquids and antiacid drugs in 30 minutes prior to administration of drug. During Ventrisol's reception it is not recommended to take alcohol. Ventrisol reduces absorption of drugs of a tetracycline row. At joint reception of Ventrisol with other HP containing bismuth risk of development of side effects increases. Reception of antiacid HP reduces Ventrisol's efficiency.

Terms of sale

Prescription issue.

Storage conditions

At a temperature up to 25 °C.

Period of validity

24 months.

Ventrisol's analogs

De-Nol, Bisnol, Trimo, Pilotsid, Tribimol. With similar therapeutic action treat drugs: Gastrotsepin, Alantonum, Kalankhin, Geviskon, Venter, Dalargin, Vicalinum, Gastrofarm.

About Ventrisole

As drug is absent in pharmacy chain and practically the patient About drug on the Internet is not appointed are absent.

Section: Gastrointestinal
in more detail

Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

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