Vero-Tamoksifen

Веро-Тамоксифен Drug photo

The description is actual on 15.05.2014

  • Latin name: Vero-Tamoxifen
  • ATH code: L02BA01
  • Active ingredient: Tamoxifenum (Tamoxifen)
  • Producer: JSC Verofarm, Russia

Structure

There are two types of dosages of Vero-Tamoksifena:

  • in one tablet of active ingredient (Tamoxifenum) of 10 mg;
  • in one tablet of Tamoxifenum of 20 mg.

Release form

Tablets contain in planimetric packagings, on 10 units in everyone. Packagings cardboard on 10,30, 50 and 100 pieces or glass jars with the same quantity of medicine.

Pharmacological action

Antineoplastic means.

Pharmacodynamics and pharmacokinetics

Active ingredient inhibits process of production of estrogen, I influence, mainly target organs. Thus there is a delay of development of a tumor.

Drug has property to be metabolized in a liver. A conclusion of the fulfilled substances (N-dezmetiltamoksifena and 4 hydroxytamoxifenums) is made mainly through a gastrointestinal tract (with a fecal masses).

Indications to use of Vero-Tamoksifena

Medicine is appointed for a cancer therapy, various etymology:

Contraindications

Drug is not appointed at pregnancy and feeding, thrombophlebitis, a medicinal allergy to its components.

Side effects

  • nausea, cholestasia, hepatitis, vomiting;
  • thrombocytopenia, leukopenia;
  • depression, bad mood, dizziness, headache;
  • hypostases, phlebitis;
  • bloody allocations from a vagina;
  • allergic reactions on skin;
  • the increased body temperature, inflow, vaginal bleedings;
  • cataract, changes in an eye retina, deterioration in sight.

Application instruction of Vero-Tamoksifena (Way and dosage)

The doctor, depending on degree and weight of an illness has to appoint a dosage and a course of drug intake.

Usually daily dose is equal to 20-30 mg, it is divided into 2 receptions. Treatment happens before emergence of positive or negative changes in analyses.

Overdose

Overdose cases are not registered by medicine. However, at its emergence strengthening of side effects is the most probable. Treatment – according to the shown symptoms.

Interaction

At a concomitant use with the tablets raising pH in a stomach it is necessary to observe an interval at 2 o'clock between both drugs.

The combination to cytostatics increases probability of formation of blood clots.

With care to combine with warfarin and other means of a number of coumarin.

The drugs containing estrogen reduce efficiency of Vero-Tamoksifena.

Terms of sale

As well as upon purchase of other antineoplastic means, existence of the recipe is required.

Storage conditions

Not to give in hands to children. To store in the dry, cool place.

Period of validity

2 years.

Analogs

Coincidence on the ATH code of the 4th level:

Tamoxifenum health, fazlodeks, Tamoxifenum to an ebeva, fareston, zitazonium.

Responses on Vero-Tamoksifen

Responses are positive. Medicine is actively used for prevention of recurrence, after operative measures at malignant new growths. Generally complain of hard transferable side effects. As a rule, after half a year of administration of drug the organism gets used and the strong discomfort passes. Some read that drug of foreign production is less toxic.

Section: Hormonal
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