Верошпилактон Drug photo

The description is actual on 04.07.2016

  • Latin name: Verospilactone
  • ATH code: C03DA01
  • Active ingredient: Spironolactonum (Spironolactone)
  • Producer: Obolenskoye — the pharmaceutical enterprise (Russia)


TabletsSpironolactonum, magnesium stearate, milk sugar, potato starch, silicon dioxide colloid, talc.

CapsulesSpironolactonum, 2% titanium dioxide, gelatin.

Release form

  • Tablets of 25 mg of white color of a round form, ploskotsilindrichesky, inodorous, in the blister packaging, in a cardboard pack No. 20 and 40.
  • Capsules gelatinous 25,50,100 mg, in the blister packaging, in a cardboard pack No. 10, 30, 50.

Pharmacological action

Diuretic, hypotensive.

Pharmacodynamics and pharmacokinetics


Drug is an antagonist of Aldosteronum and belongs to group of kaliysberegayushchy diuretics. Spironolactonum in nephrons interferes with a delay of sodium of water of aldosteronomas and the removing action of Aldosteronum suppresses potassium.

Drug contacts Aldosteronum receptors, strengthens process of allocation of ions of chlorine, sodium and water with urine, reduces removal of ions of urea and potassium and acidity of urine. The medical effect comes in 7 hours and not less days proceed. The hypotensive effect is caused by diuretic action.


Drug is quickly soaked up from a gastrointestinal tract and transformed to active metabolites. Communication with blood proteins high (about 98%). Cmax in blood is reached in 3 hours. Spironolactonum poorly gets into fabrics and bodies, and its metabolites get through GEB and into breast milk. The elimination half-life of Spironolactonum makes 12-20 hours, its metabolites — till 16 o'clock. It is removed in the form of metabolites (50%) and in an invariable view (10%) with urine and partially with a stake.

Indications to use

  • hypostases of various genesis (at cirrhosis, HSN, a nephrotic syndrome, hypostases at pregnancy in II and III trimesters);
  • arterial hypertension;
  • premenstrual syndrome and polycystosis of ovaries, hirsutism;
  • primary hyper aldosteronism;
  • hypopotassemia at treatment by saluretics and its prevention;
  • Aldosteronum the producing adenoma of adrenal glands.


Hypersensitivity to drug, Addison's illness, HPN, an anury, a hyperpotassemia, a diabetes mellitus, a hyponatremia, a hypercalcemia, morbidity of mammary glands, the I trimester of pregnancy, a metabolic acidosis, a liver failure, disturbance of a menstrual cycle. To take with caution aged after 60 flyings, at cirrhosis.

Side effects

Dizziness, headache, drowsiness, block, nausea, abdominal pain, vomiting, gastritis, bleedings in a gastrointestinal tract, diarrhea, intestinal colic, increase of level of urea, decrease in a potentiality, a giperkreatininemiya, an alkalosis or acidosis, thrombocytopenia, an agranulocytosis.

At reception of Spironolactonum for a long time — disturbance of an erection, a dysmenorrhea, an amenorrhea, a gynecomastia, a hirsutism, morbidity and increase in mammary glands, voice coarsening, local allergic reactions, a breast cancer.

Veroshpilakton, application instruction (Way and dosage)

Capsules/tablets accept after meal. The daily dose can be taken for one or several receptions. The drug dosage (initial and supporting) is selected individually depending on a disease, portability of drug and age of the patient.

Hypostases against HSN: an initial dose of 25 mg/days, maximum — 100 mg.

Hypostases at cirrhosis: the dose is selected depending on a ratio of sodium and potassium and varies within 100-400 mg/days.

Hypostases at a nephrotic syndrome: daily dose of 100-200 mg.

At essential hypertensia: daily dosage of 50-100 mg. If necessary it is gradually possible to increase a dose to 200 mg. Duration of administration of drug is not less than two weeks.

To children daily appoint at the rate of 3 mg/kg of weight and divide it into 1-2 receptions.


It is shown by drowsiness, nausea, vomiting, confusion of consciousness, diarrhea, skin rash. Less often dehydration of an organism and disturbance of electrolytic balance meets.


Spironolactonum at a concomitant use with anticoagulants reduces their efficiency. Drug increases effect of anti-hypertensive drugs and diuretics. At at the same time reception of Spironolactonum with the HP containing potassium and potassium additives APF inhibitors, kaliysberegayushchy diuretics the risk of development of a hyperpotassemia increases.

Against administration of drug toxicity of cardiac glycosides decreases. Spironolactonum lowers sensitivity of blood vessels to Norepinephrinum. Reception of diuretics and GKS accelerates and strengthens natriuretic and diuretic effect of Spironolactonum.

Indometacin, salicylates — diuretic effect of Spironolactonum reduce.

At a concomitant use of Veroshpiron and drugs of lithium toxic action of the last amplifies.

Terms of sale

Prescription issue.

Storage conditions

At a temperature up to 30 °C.

Period of validity

2 years.

Veroshpilakton's analogs

Coincidence on the ATH code of the 4th level:

Veroshpiron, Aldopur, Spiriks, Spironobene, Spironolactonum, Spironaksan, Spironol, Prakton, Vero-Spironolakton, Urakton, Spironolakton-Ratiofarm.

About Veroshpilaktona

About drug mainly positive. Patients note its high performance.

  • "… Veroshpilakton's use well removes hypostases at my bouquet of sores: idiopathic hypertensia of chronic heart failure".

Some note development of side effects, in particular, from a gastrointestinal tract. Sometimes at forums ask a question: Veroshpiron and Veroshpilakton have essential distinctions or not? There are no essential distinctions between them, except a dosage and producers.


  • Veroshpilakton of 25 mg No. 20 tabletkiobolensky FP
  • Veroshpilakton of 50 mg No. 30 kapsulyobolensky FP
  • Veroshpilakton of 100 mg No. 30 kapsulyobolensky FP
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  • Veroshpilakton of 25 mg No. 20 of the tab. of Obolenskoye - the pharmaceutical enterprise (Russia)
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Section: Diuretic Cardiovascular
in more detail

Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Veroshpilakton surely consult with the attending physician.