Vitaprost Plus

Витапрост Плюс Drug photo

The description is actual on 17.12.2014

  • Latin name: Vitaprost Plus
  • ATH code: G04BX
  • Active ingredient: Lomefloksatsin + Prostates extract (Lomefloxacin + Prostate extract)
  • Producer: NIZHPHARM, JSC (Russia)

Structure

The structure of one candle of Vitaprost Plus as active agents includes 100 mg of extract of a prostate and 400 mg of a hydrochloride of a lomefloksatsin.

Additional substances: fat firm before receiving a candle weighing 2.25 grams.

Release form

Rectal candles of Vitaprost Plus have the torpedo-shaped form, white or white-brown color.

Five such candles in planimetric packaging; 1 or 2 such packagings in a pack from paper.

Pharmacological action

Candles of Vitaprost Plus possess antiinflammatory, antibacterial and prostatotropny action.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Vitaprost Plus – the combined means with antiinflammatory and antibacterial action used at damages of a prostate gland.

Lomefloksatsin – antibacterial agent of a wide range of bactericidal action, treats group of ftorkhinolon. Affects DNK-girazu enzyme of bacteria, DNA, responsible for superspiralling, breaks replication and a transcription of DNA that leads of cells of a bacterium to death.

Possesses high activity concerning aerobic gram-negative microorganisms: Klebsiella pneumoniae, Proteus vulgaris, Neisseria meningitidis, Neisseria gonorrhoeae, Escherichia coli, Citrobacter diversus, Shigella spp., Salmonella spp., Moraxella morganii, Enterobacter cloacae, Pseudomonas aeruginosa, Haemophilus parainfluenzae, Haemophilus influenzae, Legionella pneumophila.

Serratia liquifaciens, Staphylococcus epidermidis, Serratia marcescens, Chlamydia trachomatis, Hafnia alvei, Aeromonas hydrophila, Mycobacterium tuberculosis, Citrobacter freundii, Proteus mirabilis, Providencia rettgeri, Proteus stuartii, Providencia alcalifaciens, Enterobacter aerogenes, Klebsiella ozaenae, Klebsiella oxytoca, Enterobacter agglomerans possesses moderate activity concerning Staphylococcus aureus.

Streptococcus spp., Treponema pallidum, Mycoplasma hominis, Ureaplasma urealyticum, Pseudomonas cepacia and anaerobic bacteria are steady against drug.

lomefloksatsin affects the vast majority of bacteria in small concentration (usually to 1 mkg/ml). Development of resistance comes to light seldom.

Extract of a prostate has organotropic action on a prostate. Lowers degree of hypostasis, an infiltration leukocytes, brings secretory function to a physiological state, increases amount of lecithin grains, strengthens a muscle tone of walls of a bladder. Brakes a thrombogenesis, shows antiagregantny activity, interferes with thrombosis of venules in a prostate. Normalizes clinical characteristics of a prostate and an ejaculate. Reduces pain and discomfort, activates copulative function.

Pharmacokinetics

There are no data on pharmacokinetics of means of Vitaprost Plus.

Indications to use

  • Acute or chronic prostatitis of infectious character which is caused by microorganisms, sensitive to a lomefloksatsin, including followed by diseases of urinogenital system of inflammatory character.
  • Before and after surgeries on a prostate.

Contraindications

With extra care to use drug at epilepsy, cerebral atherosclerosis or other defeats of a nervous system with an epileptic syndrome.

Side effects

Side effects of means, except for hypersensitivity reactions, are connected with presence at its structure of a lomefloksatsin.

  • Reactions from a nervous system: nervousness, adynamy, dizziness, uneasiness, fatigue, headache, syncopal states, hallucinations, sleeplessness, spasms, tremor, hyperkinesias, paresthesias, depression.
  • Reactions from immunity: photosensitization, itch, urticaria, Stephens-Johnson's syndrome.
  • Reactions from system of digestion: dryness mucous oral cavities, pseudomembranous coloenteritis, diarrhea, dysbacteriosis, lock, change of coloring of language, meteorism, loss of appetite, food faddism, activation of hepatic transaminases.
  • Reactions from the blood circulatory system: pressure decrease, bradycardia, tachycardia, ekstrasistoliya, aggravation of a course of heart failure, cardiomyopathy, arrhythmias, thrombembolia of a pulmonary artery, phlebitis.
  • Reactions from bodies of the hemopoietic system: gastrointestinal bleedings, thrombocytopenia, strengthening of a fibrinolysis, purple, limfoadenopatiya, nasal bleeding.
  • Reactions from urinogenital system: dysuria, glomerulonephritis, polyuria, albuminuria, anury, urethral bleedings, ischuria, hamaturia, crystalluria, orchitis, epididymite.
  • Reactions from a musculoskeletal system: vasculitis, arthralgia, shin myotonia, lyumbalgiya, thoracalgia.
  • Reactions from a metabolism: gout, hypoglycemia.
  • Reactions from respiratory system: bronchospasm, short wind, cough, grippopodobny symptoms.
  • Reactions from sense bodys: sonitus, vision disorder.
  • Other reactions: perspiration, thirst, fever, superinfection.

candles of Vitaprost Plus, application instruction (Way and dosage)

To apply rektalno, one candle of times a day after an enema or defecation. Before use suppository needs to be extracted from planimetric packaging. After drug use the patient is recommended to be in horizontal position within 40 minutes.

Duration of treatment is defined by disappearance of activators in juice of a prostate and usually makes from one to four weeks (is defined for each patient individually).

Overdose

There are no messages on overdose cases now.

Interaction

Features of interaction with other drugs are not studied.

Terms of sale

Drug can be bought without recipe.

Storage conditions

  • To protect from children.
  • To store in the dark dry place at a temperature up to 20 degrees.

Period of validity

Two years.

Special instructions

During treatment Vitaprostom Plus it is necessary to limit combined use of other ftorkhinolon in order to avoid overdose and development of side effects.

During treatment light needs to avoid long stay on solar and use of artificial ultra-violet lighting.

During therapy patients need to observe extra care at management of motor transport.

Analogs

Analogs of Vitaprost Plus: Vitaprost, Tutukon, Speman, Vitaprost Forte, Gentos, Kanefron of N, Lespefril, Tribestan, Urokran, Tsisto-Aurin.

Zdravzona

  • Vitaprost plus No. 10 svechinizhfarm joint stock company
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Apteka24

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Paniapteka

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Section: Urological
in more detail

Education: Graduated from the Vitebsk state medical university majoring in "Surgery". At university headed Council of students' scientific society. Professional development in 2010 - in "Oncology" and in 2011 - in "A mammology, visual forms of oncology".

Experience: Work in an all-medical network 3 years the surgeon (The Vitebsk hospital of an emergency medical service, Lioznensky TsRB) and in combination the regional oncologist and the traumatologist. Work farm the representative within a year in the Rubicon company.

Provided 3 improvement suggestions on the subject "Optimization of an Antibioticotherapia depending on Species Composition of Microflora", 2 works took prizes in a republican competition review of student's scientific works (1 and 3 categories).
PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before use of medicine of Vitaprost Plus surely consult with the attending physician.