Iodantipyrine

Йодантипирин Drug photo

The description is actual on 27.07.2016

  • Latin name: Iodantipirin
  • ATH code: J05AX
  • Active ingredient: Yodofenazon (Iodophenazone)
  • Producer: JSC Farmstandart-Tomskhimfarm (Russia)

Structure

Yodofenazon, glucose, low-molecular polyvinylpirrolidone, potato starch, magnesium stearate.

Release form

Tablets ploskotsilindrichesky white color in the blister in a cardboard pack No. 50.

Pharmacological action

Antiviral, antiinflammatory, immunomodulatory.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Drug has an antiinflammatory, interferongenny and immunopromoting effect. Interferes with penetration of a virus into cells, stabilizes cellular membranes. The alpha and a beta of interferon belongs to inductors, increases humoral and cellular immunity. Shows high activity concerning the causative agent of tick-borne encephalitis, and also fever hemorrhagic with a renal syndrome.

Pharmacokinetics

Drug is well soaked up from a gastrointestinal tract, bioavailability about 80%. It Biotransformirutsya in a liver. Linkng with blood proteins — 25%. About 8 hours are brought out of an organism with urine mainly in the form of pharmacological inactive metabolites with an elimination half-life.

Indications to use

In complex therapy and as a prophylactic from a tick-borne encephalitis and fever hemorrhagic with a renal syndrome.

Contraindications

High sensitivity to drug, diseases of kidneys and a liver, hyperfunction of a thyroid gland, children's age, the period of pregnancy and a lactation.

Side effects

In rare instances an itch and rash on skin, dispeptic manifestations, allergic reactions.

Iodantipyrine, application instruction (Way and dosage)

To take a pill inside, in time or after food. At a tick-borne encephalitis the dosage of drug makes 0,3 g the 3rd time/day in the first 2 days; 0,2 g the 3rd time/day for the third or fourth days and on 0,1 g the 3rd time/day in the next 5 days.

For the purpose of prevention at detection of the stuck tick the scheme of administration of drug is similar. At stay in places, epidemiologically unsuccessful on a tick-borne encephalitis on 0,2 g/day before visit of such places and for the entire period of stay.

Overdose

Signs of an iodism or emergence of side effects are extremely seldom noted.

Interaction

At a concomitant use with glucose-lowering drugs, tricyclic antidepressants, barbiturates, anticoagulants Yodantipirin strengthens their action, forcing out them from communication with proteins. Antagonists of receptors of H2 — antiacid HP slow down drug absorption.

Terms of sale

Prescription sale.

Storage conditions

At a temperature up to 25 °C.

Period of validity

36 months.

Yodantipirin's analogs

Kagotsel, Amizon, Altabor, Imustat, Panavir, Detoksopirol, Flavia, Ingavirin, Proteflazid, Erebra and others.

About Yodantipirin

About drug for treatment of a tick-borne encephalitis among patients rather contradictory. The majority is used by Yodantipirin as a prophylactic at backpackings, collecting mushrooms, fishing. In general, according to specialists Yodantipirin's use in a complex with interferon drugs at a disease of a tick-borne encephalitis provides effective etiotropic treatment. Some visitors of forums recommend to use Yodantipirin at flu, a SARS. It is not necessary to do it as only the doctor can appoint treatment.

Zdravzona

  • Iodantipyrine 100 of mg No. 50 tabletkifarmstandart-Tomskhimfarm joint stock company
  • Iodantipyrine 100 of mg No. 20 of a tablet
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Section: Immunity increase Antiviral
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Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before medicine use Yodantipirin surely consult with the attending physician.