Yoks

Йокс Drug photo

The description is actual on 03.01.2015

  • Latin name: Jox
  • ATH code: R02AA20
  • Active ingredient: Cordianine + Povidone-iodine (Allantoinum + Povidonum-Iodum)
  • Producer: IVAX Pharmaceuticals (Czech Republic)

Structure

In 100 ml of solution for topical administration 8,5 g povidone-iodine and 0,1 g of cordianine contain. As excipients are used: monohydrate of citric acid (0.1 g), left menthol (0,5 g), a citrate sodium dihydrate (0,1 g), and also 10 g of 96 percent ethanol, 15 g of propylene glycol and 50 g of the purified water.

In 30 ml of spray 2,55 g povidone-iodine and 0,03 g of cordianine contain. As excipients such components as monohydrate of citric acid, left menthol, a dihydrate of sodium of citrate, 96% ethanol, propylene glycol and the purified water are also used.

Release form

Solution of red-brown color (volume of 50/100 ml) is issued in the bottles made of dark glass with propylene covers on one in a cardboard pack. For protection of integrity of packaging control of the first opening, and for usability — a measured cap is provided.

Spray (volume — 30 ml) is issued in bottles from polyethyleneterephthalate, they are equipped with mechanical sprayers and have covers for protection of the sprayer. Drug is packed into a cardboard pack and completed with the applicator with the rotary lever.

Pharmacological action

Possesses antiseptic and antiinflammatory action.

Pharmacodynamics and pharmacokinetics

Povidone-iodine is the disinfecting substance representing an iodine complex with polividony — the high-molecular connection capable to reduce toxic impact of iodine on organism cells. It is characterized by a wide range of antimicrobic action at the expense of a direct impact on proteins of microorganisms (proteolytic properties). Possesses partially bactericidal action on gram-positive both gram-negative cooks and bacilli, and also on separate anaerobic bacteria, yeast, besides – on the elementary viruses.

Cordianine is capable to exert antiinflammatory impact that in a complex with polividony gives therapeutic effect.

Drug easily gets into layers of an epithelium mucous respiratory tracts, gives fast effect at acute and chronic diseases.

Iodine in an organism turns into iodides which generally accumulate in a thyroid gland. They are brought mainly by kidneys and in a small amount with excrements, sweating and salivation.

Indications to use

  • infectious and inflammatory processes in an oral cavity and a drink, including quinsy, tonsillitis, tonzilofaringit, a glossitis and aphthous stomatitis;
  • processing of an oral cavity and throat at surgical intervention on the pneumatic ways and an oral cavity, and also during the postoperative period;
  • first symptoms of flu;
  • treatment of various infections of an oral cavity and the throat arising owing to chemotherapy;
  • streptococcal quinsy (in a complex with antibiotics).

Contraindications

  • disturbances of functioning of a thyroid gland, for example hyperthyroidism;
  • dekompensirovanny heart failure;
  • renal failure;
  • dermatitis of Dyuringa (herpetiform defeats);
  • simultaneous use of a radioiodine, interval before treatment by Yoks not less than 2 weeks;
  • age till 6 flyings;
  • pregnancy or lactation (breastfeeding);
  • hypersensitivity to components of drug of Yoks.

Side effects

Allergic reactions at the established hypersensitivity to any of components of drug of Yoks which are shown in the form of an itch, the small tortoiseshell, dryness in a mouth and a hyperemia are possible, extremely seldom there is a Quincke's disease. At these reactions drug withdrawal is recommended.

Prolonged use can lead to the phenomenon of an iodism and emergence of metal taste, the increased salivation, hypostasis a century and throats.

Application instruction of Yoks (Way and dosage)

Both solution, and spray apply locally. It is recommended to dilute solution with water in a proportion 1 to 20 - 1 to 40, that is 2,5 ml or 5 ml (to measure the measured cap which is available in drug packaging), or 0,5–1 chayn. spoons in 100 ml of water. The received solution it is necessary to rinse an oral cavity and drinks 2–4 times a day, if necessary more frequent use — to 6 times a day with the minimum interval between rinsings of 4 h is admissible.

The application instruction of spray of Yoks is consolidated to algorithm:

  • to wash out the applicator hot water;
  • to remove a cap, to install the applicator, to press several times on the applicator that solution came to the sprayer and it could be sprayed after the subsequent pressing;
  • then to place an applicator tube in an oral cavity approximately on 2–3 cm in depth;
  • having held the breath, to press 2 times a cap for an irrigation for the first time – on the right side, in the second – on the left side of an oral cavity.

Spray is usually used by 2-4 times a day. The interval at more frequent use has to be not less than 4 h.

Duration of a course of treatment has to be determined by the attending physician depending on nature of course of an illness.

Overdose

Information on overdose at topical administration is not available.

Interaction

It is inexpedient to use with the antiseptic agents containing hydrogen peroxide as the probability of an inactivation of active agents is high.

Simultaneous use with lithium causes additional hypothyroid effect.

It is not desirable to apply with hlorgeksimidy, silver Sulfadiazinum, alkaloid salts and mercury.

Iodine is not compatible with:

  • iron salts;
  • bismuth;
  • copper;
  • lead;
  • potassium chlorate and other oxidizers;
  • mineral acids;
  • strychnine hydrochloride;
  • sulfate of quinine and other alkaloidal salts.

Terms of sale

Drug is released without recipe.

Storage conditions

In the dry dark place not available to children, at a temperature of 10-25 a °tselsiya.

Period of validity

In the form of solution till five years, in the form of an aerosol – no more than four years.

Special instructions

Drug should not be accepted inside, including to inhale or swallow as makes sick, vomiting, diarrhea, development of acute poisoning is possible.

At local drawing on complete covers absorption of iodine is minimum while use of spray of Yoks in an oral cavity leads to more expressed and system absorption of iodine owing to what emergence of an interference with tireoidalny functions is possible.

Contains about 18,6% of ethanol.

Yoks at pregnancy and a lactation

Active ingredients are capable to break a placental barrier and to get into breast milk therefore drug is not recommended to be used at pregnancy, and also to women who nurse.

About Yoks

Drug is popular today, many note its efficiency and always keep in the home first-aid kit.

Patients leave positive About Yoks, pointing to convenience and simplicity of use of an aerosol and speed of occurrence of therapeutic effect (within a day). Of course, there are patients who give preference to traditional rinsings where Yoks thanks to active agents is effective at various inflammatory and infectious processes of an oral cavity and a throat.

It is possible to meet not numerous negative About drug, connected with side allergic reactions: itch, burning, dacryagogue.

Yoks's price where to buy

The price of spray of Yoks (30 ml) makes 265-325 rubles, solution (50 ml) – 165-205 rubles.

Zdravzona

  • Yoks-Teva of 50 ml solution for an outside primeneniyatev the Pharmaceutical Enterprises of Ltd.
  • Yoks-Teva of 30 ml an aerosol for a local primeneniyatev the Pharmaceutical Enterprises of Ltd.

Drugstore of IFC

  • Yoks solution naruzhn. 50 ml, IVAX Corporationchekhiya
  • Yoks aer 30 ml, Galena/IVAX Corporationchekhiya
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Apteka24

  • YOKSIVAX Pharmaceuticals (Czech Republic)

Paniapteka

  • Yoks ml solution 50

BIOSPHERE

  • Yoks 50 ml r-rteva Czech Enterprises of neuter of the lake (Czech Republic)
  • Yoks 30 ml of a spreytev Czech Enterprises of neuter of the lake (Czech Republic)
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Section: Antiseptic agents
in more detail

Education: Graduated from the Nikolaev national university of V. A. Sukhomlinsky, gained the diploma of the specialist with honors as "An embryologist, a cytologist, a histologist". Also, the human physiology and animals, the teacher of biology" graduated from a magistracy majoring in ". The course on discipline "Pharmacology" is with honors passable.

Experience: Worked as the senior laboratory assistant of department of Physiology and biochemistry of the Nikolaev national university of V. A. Sukhomlinsky in 2010 - 2011.

PAY ATTENTION! Information on drugs on the website is help generalizing, collected from public sources and can form the basis for making decision on use of medicines it is not aware of treatment. Before use of medicine of Yoks surely consult with the attending physician.