It is mirror

Зеркалин Drug photo

The description is actual on 30.01.2015

  • Latin name: Zerkalin
  • ATH code: D10AF01
  • Active ingredient: Clindamycin (Clindamycin)
  • Producer: Jadran Galenski Laboratorij (Republic of Croatia)

Structure

Clindamycin a hydrochloride of 1,14 g in 100 ml.

Ethanol, propylene glycol, the water purified as excipients.

Release form

1% spirit solution.

Pharmacological action

Antimicrobic.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Active ingredient of this drug clindamycin is the antibiotic showing activity concerning strains of the bacteria causing eels. It suppresses reproduction of Propionibacterium acnes, found in follicles and sebaceous glands. Clindamycin suppresses protein synthesis of a microbic cell, interacting with 50S-subunits of ribosomes. Antiacne action is explained also by decrease in free fatty acids skin.

Pharmacokinetics

It is mirror collects and it is long it is found in comedones where shows the antibacterial activity. The minimum overwhelming concentration for Propionibacterium acnes — 0,4 mkg/ml. And average concentration of an antibiotic in comedones after their processing considerably exceeds this indicator. At external use system absorption is insignificant therefore extremely low concentration of active ingredient are defined in blood and urine.

Indications to use

Treatment of an acne (acne rash).

Contraindications

  • pseudomembranous colitis;
  • hypersensitivity to clindamycin or other linkosamida;
  • illness Krone;
  • lactation period;
  • concomitant use of muscle relaxants;
  • age till 12 flyings.

Side effects

Zerkalin's solution in a site of application can cause irritation, reddening, a xeroderma, burning, a peeling. Perhaps increased allocation of a skin secret. At absorption there is a probability of emergence of diarrhea, an abdominal pain and rather seldom the pseudomembranous coloenteritis develops. At hit in eyes — a burning sensation in them.

The instruction on Zerkalin (A way and a dosage)

It is applied outwardly. The struck area before putting drug needs to be cleared and dried up. Apply on skin in the morning and in the evening. For receiving effect treatment is continued by 1,5-2 months, if necessary — 6 months.

The application instruction contains the warning that it is necessary to avoid contact of solution from spots with eyes and an oral cavity. It is necessary to wash up well hands after its use. At accidental contact of drug with these areas of a body, it is necessary to wash out plentifully them water.

Overdose

Overdose is improbable as at topical administration of drug absorption is minimum.

Interaction

Solution should not be applied together with the disinfecting and peeling means to skin and the soaps containing abrasive substances in a look of the fact that strengthening of the irritating and drying up action is possible.

Clindamycin and Erythromycin (lotion Sinnerite, gel Izotreksin) are antagonists therefore their simultaneous use is not recommended. At systemic action drug strengthens action of muscle relaxants.

Terms of sale

Without recipe.

Storage conditions

At a temperature no more than 250C.

Period of validity

2 years.

Zerkalin's analogs

Coincidence on the ATH code of the 4th level:

Zerkalin's analogs having one active ingredient, gels of Klindovit, Dalatsin of T, Klindovit, Klindatop, Klenzit-page.

About Zerkalin

Those who applied Zerkalin from spots Leave positive. At treatment in several days the quantity of elements decreases by 50%, reddening and an inflammation disappears. Outside therapy usually does not cause hypersensitivity of skin and system side effects do not meet. All note that this drug is much more effective, than means on the basis of Tetracycline, for example Unguentum Tetracyclini. Drug is called "the savior of skin", said that "noticed real effect" and that "Zerkalin coped with a problem which 5 years could not solve".

Is About Zerkalin at the heavy course of an acne illness. It is noted that in this case treatment only by local use of an antibiotic not really effectively and irrationally — drug does not exert impact on all links of a pathogeny of eels. Purpose systemically of the operating antibiotics, retinoids and hormones is necessary. Also, at prolonged topical treatment there is a risk of development of resistance of pathogenic flora.

Zdravzona

  • The bottle-kapelnitsayadran Galensky Laboratory of the joint-stock company is mirror 10mg/ml solution for external use of 30 ml

Drugstore of IFC

  • Solution for external menen.10mg/ml fl 30 ml is mirror, Jadrankhorvatiya
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Section: Antibiotics Dermatological
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Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

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