Duo-Aktiv zovirax

Зовиракс Дуо-Актив Drug photo

The description is actual on 06.07.2016

  • Latin name:  Zovirax Duo-Activ
  • ATH code: D06BB03
  • Active ingredient: Acyclovir + Hydrocortisone (Aciclovir + Hydrocortisone)
  • Producer: Contract Pharmaceuticals Ltd (Canada)

Structure

In 1 g of cream of 50 mg of an acyclovir and 10 mg of a hydrocortisone.

Liquid paraffin, soft paraffin, isopropyl myristate, cetostearyl alcohol, sodium lauryl sulfate, half-oxameasures, monohydrate of citric acid, propylene glycol, Acidum hydrochloricum, sodium hydroxide, the water purified — as auxiliary components.

Release form

External use cream in aluminum tubas on 2 g and 5 g.

Pharmacological action

Antiviral and antiinflammatory.

Pharmacodynamics and pharmacokinetics

Pharmacodynamics

Duo zovirax the Asset — the combined antiviral drug containing an acyclovir and a hydrocortisone.

The acyclovir shows activity concerning a virus Epstein-Barre, Varicella zoster, Herpes simplex (1 and 2 types). Inhibits replication of viruses. When drawing on skin the acyclovir under the influence of a thymidinekinase of the cells infected with a virus will be transformed in mono - di - and triphosphate which joins in a chain of DNA of viruses, as leads to blocking of replication of new generations.

Hydrocortisone — the slaboaktivny glucocorticosteroid showing antiinflammatory, anti-exudative and antipruritic action. The combination of these substances prevents formation of herpetic rashes (on condition of use in a prodromal stage) and reduces terms of their healing.

Pharmacokinetics

At topical administration the acyclovir is slightly absorbed.

Hydrocortisone, getting through a corneous layer of epidermis, it is also slightly absorbed. Suppression gipotalamo - pituitary and adrenal system when using of the recommended doses of drug is not noted.

Indications to use

Recurrent herpes infection (Herpes simplex) of skin of lips at adults and children since 12.

Contraindications

  • fungal and bacterial damages of skin, and also caused by other viruses;
  • hypersensitivity to an acyclovir;
  • skin tumors;
  • rozatsea;
  • perioral dermatitis;
  • vulgar eels;
  • age till 12 flyings.

Side effects

The met side reactions are more often:

  • skin peeling;
  • xeroderma;
  • short-term burning and itch.

The met side reactions are more rare:

Application instruction (Way and dosage)

Cream Duo Zovirax the Asset is intended only for external use. It is important to begin treatment in a prodromal stage — at the first emergence of burning, a pricking, puffiness of skin of lips. It should be put to 5 times a day with a break for the night. Put with a thin layer, taking healthy sites of skin. Treatment is carried out by 5 days.

At preservation of symptoms there is more this span, and also at the expressed displays of an infection it is necessary to see a doctor. For the prevention of a transmission of infection it is necessary to wash hands after drug use, not to touch with a towel affected areas.

It is not recommended to apply cream on mucous a mouth, eyes, genitalias. It is impossible to use plasters and bandages on a cream site of application. Content of cetostearyl alcohol and propylene glycol in cream can cause irritation of skin and contact dermatitis.

Overdose

Overdose was not observed even at one-time use of all contents of a tube or at an accidental proglatyvaniye.

Interaction

At outside use of interaction with other medicines it is not revealed.

Terms of sale

It is released without recipe.

Storage conditions

Temperature of storage is up to 25 °C. It is impossible to store in the refrigerator.

Period of validity

2 years and 3 months after opening of a tuba.

Analogs

Structural analogs Duo Zovirax the Asset does not exist. Similar action and the indication to use have the Acyclovir, Atsigerpin, Vivoraks, Gerpferon, Gerperaks.

About Duo Zovirax Asset

The main place in antiviral treatment of a herpes simplex is allocated to the acyclic nucleosides containing an acyclovir. There is a lot of these drugs: Zovirax, Valtreks, Acyclovir Acre, Famvir, Gerperaks.

Duo zovirax the Asset favourably differs from other means in existence in structure of a hydrocortisone which considerably reduces an inflammation, hypostasis, pain and unpleasant feelings of a raspiraniye in the field of herpetic rashes.

About drug versatile. Some patients do not note special effect at its use that it is probably connected with individual sensitivity, time of an initiation of treatment and frequency rate of use. Besides, at recurrent herpes and continuous use of an acyclovir sensitivity of a virus to it and efficiency of treatment decreases.

  • "… Always used simple Zovirax, but decided to try Duo-Aktiv. It helped to clean rashes in 4 days – for me it is record terms as tried many ointments. The price is decent, considering that cream only of 2 g, but it is worth it".
  • "… It is necessary to pay tribute — Duo Zovirax the Asset perfectly coped with a task though applied it only for the 3rd day. After the first drawing it became easier — hypostasis, pain decreased, already formed crusts were softened".
  • "… Processed rashes only 2 times a day instead of five, and they passed in 3 days!!! There is no trace left also. I think if to apply more often, will pass even quicker. I recommend to all!".
  • "… Smeared with cream three times a day, effect any — the sixth day, and herpes all the same did not pass. Did not notice acceleration of treatment of herpes".
  • "… And neither it, nor analogs with an acyclovir help me".

Zdravzona

  • Duo-Aktiv zovirax cream 2gglakso Vellk Opereyshens/glaksosmitklyay

Drugstore of IFC

  • Duo-Aktiv zovirax cream 2 of of a tube, Glaxo Wellcomevelikobritaniya
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Section: Dermatological Antiviral
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Education: Graduated from Sverdlovsk medical school (1968 - 1971) as "Paramedic". Graduated from the Donetsk medical institute (1975 - 1981) as "An epidemiologist, a hygienist". Passed postgraduate study in the Central scientific research institute of epidemiology Moscow (1986 - 1989). An academic degree – the candidate of medical sciences (degree is awarded in 1989, protection – the Central scientific research institute of epidemiology Moscow). Numerous advanced training courses are studied in epidemiology and infectious diseases.

Experience: Work as the manager of department of disinfection and sterilization of 1981 - 1992. Work as the manager of department of especially dangerous infections of 1992 - 2010. Teaching activity at Medical institute 2010 - 2013.

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